Ohio is currently home to 3199 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Cincinnati, Columbus, Cleveland and Dayton. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Safety and Tolerability Trial of Lumateperone in Pediatric Patients With Schizophrenia or Bipolar Disorder
NCT06229210
Recruiting
This is a multicenter, global, 26-week, open-label study to assess the safety and tolerability of lumateperone in pediatric patients with schizophrenia or bipolar disorder.
Gender:
ALL
Ages:
Between 10 years and 17 years
Trial Updated:
01/26/2024
Locations: Clinical Site, Cincinnati, Ohio
Conditions: Schizophrenia, Bipolar Disorder
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89Zr-girentuximab for PET Imaging of CAIX Positive Solid Tumors
NCT05563272
Recruiting
A prospective, open-label, phase 2 study to explore CAIX expression through 89Zirconium-labelled girentuximab deferoxamine (89Zr-girentuximab) PET/CT imaging in patients with solid tumors.
Gender:
ALL
Ages:
Between 18 years and 95 years
Trial Updated:
01/24/2024
Locations: University Hospitals, Cleveland, Ohio
Conditions: Cervical Cancer, Colorectal Cancer, Esophageal Cancer, Gastric Cancer, Glioblastoma Multiforme, Cholangiocarcinoma, Hepatocellular Carcinoma, Head and Neck Squamous Cell Carcinoma, Nasopharyngeal Carcinoma, Non Small Cell Lung Cancer, Small Cell Lung Cancer, Epithelial Ovarian Cancer, Pancreatic Ductal Adenocarcinoma, Soft Tissue Sarcoma
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Validation of Early Prognostic Data for Recovery Outcome After Stroke for Future, Higher Yield Trials
NCT05338697
Recruiting
VERIFY will validate biomarkers of upper extremity (UE) motor outcome in the acute ischemic stroke window for immediate use in clinical trials, and explore these biomarkers in acute intracerebral hemorrhage. VERIFY will create the first multicenter, large-scale, prospective dataset of clinical, transmagnetic stimulation (TMS), and MRI measures in the acute stroke time window.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: University of Cincinnati Medical Center, Cincinnati, Ohio
Conditions: Stroke, Stroke, Acute, Stroke, Ischemic, Stroke Hemorrhagic
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A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
NCT04849728
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: Consultants for Clinical Research - Montgomery Office, Cincinnati, Ohio
Conditions: NASH - Nonalcoholic Steatohepatitis
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Wearable Spine Health System for Military Readiness
NCT05944354
Recruiting
The goal of this observational trial is to compare the health history and motion capabilities of participants with low back pain disorders to participants with healthy spines. The main question\[s\] it aims to answer are to: 1. Primary outcomes of this research effort include the development of composite measures or digital biomarkers to track functional recovery over time and predict duty or work status outcomes (return-to-full duty/work, limited duty/work restrictions or medical discharge/lon... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
01/22/2024
Locations: The Ohio State University, Columbus, Ohio
Conditions: Low Back Pain, Neck Pain
Register for Updates
Have Physical Therapists Attitudes and Beliefs Towards Vital Assessment Changed Following the COVID-19 Pandemic?
NCT05908045
Recruiting
Previous studies prior to the COVID-19 pandemic show that cardiovascular and blood pressure assessment by physical therapists is inadequate or lacking despite prior training. Since the COVID-19 pandemic, assessment of cardiovascular and respiratory function may become more critical as the manifestation of long COVID has become a concern. The purpose of this study is to determine whether physical therapists' attitudes and beliefs towards vital sign assessment have changed following the COVID-19 p... Read More
Gender:
ALL
Ages:
Between 23 years and 100 years
Trial Updated:
01/22/2024
Locations: Youngstown State University, Youngstown, Ohio
Conditions: Vital Signs
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Sodium Thiosulfate Otoprotection During Salvage Cisplatin Therapy
NCT05756660
Recruiting
This study will attempt to demonstrate the efficacy of Sodium Thiosulfate (STS) in preventing hearing loss in patients re-treated with cisplatin-based therapy according to regimens Cisplatin and STS (regimen CS) and Cisplatin, STS and Vorinostat/SAHA (regimen CSS).
Gender:
ALL
Ages:
Between 1 month and 39 years
Trial Updated:
01/16/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Ototoxicity, Drug-Induced
Register for Updates
Natural History of Cerebral Palsy Prospective Study
NCT05576948
Recruiting
The study will describe the natural history of cerebral palsy (CP) as children develop over the first 2 years of life.
Gender:
ALL
Ages:
Between 3 months and 24 months
Trial Updated:
01/16/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Cerebral Palsy
Register for Updates
Motor Training for Infants With Cerebral Palsy
NCT04886895
Recruiting
The intervention in this study, Let's Move, is a motor intervention for infants at risk for cerebral palsy. We will test the feasibility and acceptability of the intervention as well as preliminary effectiveness.
Gender:
ALL
Ages:
Between 3 months and 8 months
Trial Updated:
01/16/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Cerebral Palsy
Register for Updates
The Half Moon Transcatheter Mitral Valve Repair (TMVr) Pilot Study
NCT04343313
Recruiting
The study is a prospective, multi-center, single-arm, non-randomized, Early Feasibility Study (EFS) to evaluate the safety and performance of the Half Moon TMVr System in patients with severe, symptomatic mitral regurgitation, who are at high risk for conventional mitral valve surgery.
Gender:
ALL
Ages:
Between 21 years and 95 years
Trial Updated:
01/10/2024
Locations: University Hospitals Cleveland Medical Center, Cleveland, Ohio
Conditions: Mitral Valve Insufficiency
Register for Updates
Violet Light for the Suppression of Myopia
NCT06110520
Recruiting
The study explores the suppression of myopia via violet light.
Gender:
ALL
Ages:
Between 5 years and 12 years
Trial Updated:
01/09/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Myopia, Phototherapy
Register for Updates
The Congenital Dyserythropoietic Anemia Registry (CDAR)
NCT02964494
Recruiting
The investigators propose the creation and maintenance of a comprehensive registry for patients with the diagnosis of Congenital Dyserythropoietic Anemia (CDA) in North America. The goal of this registry will be to collect long-term confidential data on patients with CDA in the US, Canada, and Mexico and create a bio-repository of de-identified patient blood and bone marrow specimens as a tool for the investigation of epidemiology, natural history, biology, and molecular pathogenetic mechanisms... Read More
Gender:
ALL
Ages:
All
Trial Updated:
01/09/2024
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Congenital Dyserythropoietic Anemia (CDA)
Register for Updates