Alabama is currently home to 1236 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Birmingham, Mobile, Huntsville and Anniston. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Virtual Reality Gaming for Exercise and Mindfulness Among Pediatric Cancer Rehabilitation
NCT06298357
Recruiting
This study will explore the potential benefits of a virtual reality gaming program that focuses on mindfulness and exercise among pediatric cancer rehabilitation patients. The program will last 8 weeks outside of the hospital. Participants will start immediately in the hospital (immediate start group) or wait 8 weeks after hospital discharge to start the program (waitlist control group).
Gender:
ALL
Ages:
8 years and above
Trial Updated:
05/02/2025
Locations: Children's Hospital of Alabama, Birmingham, Alabama
Conditions: Pediatric Cancer
Register for Updates
Acceptance and Commitment Therapy for Depressed People With Spinal Cord Injuries
NCT06233656
Recruiting
Living with spinal cord injury (SCI) can have a significant negative impact on an individual's mental health and restrict participation in personally valued activities and roles. Acceptance and commitment therapy (ACT) is an evidence-based approach that can lessen symptoms of mental health disorders (e.g., depressive symptoms) and improve quality of life through mindfulness and acceptance processes and behavior change processes for valued living. Evidence for ACT for individuals living with SCI,... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/02/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Depression, Spinal Cord Injuries
Register for Updates
Randomized Trial of UI-EWD vs. Conventional Endoscopic Therapy for Bleeding Ulcers
NCT06188585
Recruiting
A prospective, multi-center, noninferiority randomized controlled trial designed to compare the efficacy of UI-EWD (Nexpowder™) hemostatic powder versus conventional endoscopic hemostatic therapy in patients presenting with acute overt gastrointestinal bleeding which is found at endoscopy to be due to a gastric or duodenal ulcer with active bleeding (spurting or oozing) or a non-bleeding visible vessel.
Gender:
ALL
Ages:
22 years and above
Trial Updated:
05/02/2025
Locations: University of Alabama, Birmingham, Alabama
Conditions: Acute Gastrointestinal Bleeding
Register for Updates
Does Fluorescence With or Without Indocyanine Green Improve Parathyroid Identification and Preservation
NCT06169735
Recruiting
The aim of this study is to determine if fluorescence with or without indocyanine green can facilitate safe and accurate thyroid and parathyroid surgery.
Gender:
ALL
Ages:
19 years and above
Trial Updated:
05/02/2025
Locations: UAB Callahan Eye, Birmingham, Alabama
Conditions: Parathyroid Dysfunction, Adenoma
Register for Updates
DMSO Cryopreserved Platelets in Cardiopulmonary Bypass Surgery (CRYPTICS)
NCT04709705
Recruiting
A randomized, parallel group, active comparator-controlled trial to evaluate the non-inferiority or superiority of Cryopreserved Platelets with Liquid Stored Platelets in controlling blood loss in patients undergoing Cardiopulmonary Bypass Surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/02/2025
Locations: University of Alabama, Birmingham, Alabama
Conditions: Cardiac Surgery
Register for Updates
Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults
NCT04323046
Recruiting
This phase I trial studies the side effects of nivolumab before and after surgery in treating children and young adults with high grade glioma that has come back (recurrent) or is increasing in scope or severity (progressive). Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread.
Gender:
ALL
Ages:
Between 6 months and 25 years
Trial Updated:
05/02/2025
Locations: University of Alabama at Birmingham, Children's of Alabama, Birmingham, Alabama
Conditions: Glioblastoma, Malignant Glioma, Recurrent Glioblastoma, Recurrent Malignant Glioma, Recurrent Grade III Glioma, Grade III Glioma
Register for Updates
Safety, PK, PD, and Clinical Activity of Orally Administered KT-621 in Adult Patients With Atopic Dermatitis (AD)
NCT06945458
Recruiting
This is a study to evaluate safety, tolerability, pharmacokinetics, pharmacodynamics, and clinical activity of orally administered KT-621 in adult male and female patients with moderate to severe atopic dermatitis (AD).
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
05/01/2025
Locations: Kymera Investigative Site, Birmingham, Alabama
Conditions: Atopic Dermatitis
Register for Updates
A Phase 3 Study of Barzolvolimab in Participants With Chronic Spontaneous Urticaria
NCT06445023
Recruiting
The purpose of this study is to establish the efficacy, safety and tolerability of barzolvolimab in adult participants with Chronic Spontaneous Urticaria (CSU) inadequately controlled by non-sedating second generation H1-antihistamines in comparison to placebo.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/01/2025
Locations: Cahaba Dermatology Skin Health Center, Birmingham, Alabama
Conditions: Chronic Spontaneous Urticaria
Register for Updates
Refining the Role of Mid-induction Bone Marrow Biopsy in Acute Myeloid Leukemia: A Pilot Study
NCT06323590
Recruiting
The purpose of the study is to observe the outcomes of patients with acute myeloid leukemia who do not receive an immediate second round of chemotherapy after undergoing a standard mid-induction bone marrow biopsy.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
05/01/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Acute Myeloid Leukemia
Register for Updates
The Impact of Expressive Emotional Writing on Facilitating Grief Resolution in Adults With Spinal Cord Injury
NCT06147258
Recruiting
The aim of this study is to evaluate the therapeutic benefits of a 10-week online coach-guided EEWP on psychosocial health among adults with SCI.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/01/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Spinal Cord Injuries, Transverse Myelitis
Register for Updates
Cardiometabolic Health Intervention Using Movement-to-Music Exercise
NCT05606432
Recruiting
The study aims to test the benefits of a 24-week, cardio-emphasized Movement-to-Music exercise program for reversing cardiometabolic health risk factors compared to asynchronous, standard exercise programs among 132 adult wheelchair users. The targeted cardiometabolic health factors are waist circumference, triglycerides, "good" cholesterol, glucose, and blood pressure. Additionally, a 12-week follow-up phase (weeks 25-36) is included to see whether the gains are maintained.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
05/01/2025
Locations: The University of Alabama at Birmingahm, Birmingham, Alabama
Conditions: Cardiometabolic Risk Factors in Adult Wheelchair Users
Register for Updates
Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA
NCT04955795
Recruiting
This study is designed to examine the efficacy of a brief intervention plus a cognitive-behavioral intervention compared to brief intervention alone to address unhealthy alcohol use and comorbid mental health symptoms to improve HIV outcomes among people living with HIV in Alabama.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
05/01/2025
Locations: Health Service Center, Anniston, Alabama
Conditions: Hiv, Alcohol Problem
Register for Updates