Alabama is currently home to 1238 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Birmingham, Mobile, Huntsville and Anniston. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Isatuximab, Pomalidomide, Elotuzumab and Dexamethasone in Relapsed And/or Refractory Multiple Myeloma
NCT04835129
Recruiting
This is a multicenter, open-label phase II study in subjects with relapsed and/or refractory multiple myeloma with at least two prior lines of therapy. The main study consists of three phases: a 28-day screening phase, treatment phase that consists of 28-day cycles of isatuximab with elotuzumab, pomalidomide, and dexamethasone and a follow-up phase.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2025
Locations: The University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Multiple Myeloma
Register for Updates
Milk And Growth In Children (MAGIC) Born Very Preterm: A Randomized Trial
NCT06420531
Recruiting
The goal of this multi-center randomized, parallel group trial is to determine the effect of human milk diets ranging between 180 and 200 mL/kg/day on the body composition outcomes of moderately preterm infants born between 27 and 31 weeks of gestation.
Gender:
ALL
Ages:
Between 6 hours and 4 days
Trial Updated:
02/04/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Prematurity
Register for Updates
Developing and Evaluating a Novel Approach to Improve HPV Vaccination Coverage Among High-risk, Under-immunized Adults Via the Emergency Department
NCT06229353
Recruiting
To determine if the emergency department (ED) setting offers a viable space for improving HPV vaccination coverage among 18 to 45-year-old adults who have not yet received human papilloma virus (HPV) vaccination or who did not complete the vaccine series. This study will develop, pilot and evaluate an ED-based HPV vaccination protocol and program for ED patients aged 18-26 (for whom catch-up HPV vaccination is routinely recommended by the CDC) and separately for patients aged 27-45 (for whom it... Read More
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
02/04/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Human Papilloma Virus
Register for Updates
Hybrid Type I Effectiveness-Implementation Trial of Project nGage
NCT05723653
Recruiting
The goal of this Hybrid Type I effectiveness-implementation trial is to test Project nGage, an evidence-based, flexible, and tailored intervention that leverages existing social network members to promote retention in care and viral suppression among young Black men and women ages 18-49.
Gender:
ALL
Ages:
Between 18 years and 49 years
Trial Updated:
02/04/2025
Locations: University of Alabama at Birmingham 1917 Clinic, Birmingham, Alabama
Conditions: HIV Seropositivity
Register for Updates
HPV DNA Vaccine Via Electroporation for HPV16 Positive Cervical Neoplasia
NCT04131413
Recruiting
The primary goal of this phase I open label study is to determine the safety and tolerability of pNGVL4aCRTE6E7L2 DNA vaccine, as administered by intramuscular (IM) injection with TriGrid™ electroporation to both HIV- or HIV+ adult female subjects (≥ 19 years), with biopsy confirmed cervical intraepithelial (CIN) II or III that is human papillomavirus (HPV) 16+.
Gender:
FEMALE
Ages:
19 years and above
Trial Updated:
02/04/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Human Papillomavirus Type 16, Cervical Intraepithelial Neoplasia Grade II, Cervical Intraepithelial Neoplasia, Grade III
Register for Updates
APOL1 Long-term Kidney Transplantation Outcomes Network (APOLLO)
NCT03615235
Recruiting
The APOLLO study is being done in an attempt to improve outcomes after kidney transplantation and to improve the safety of living kidney donation based upon variation in the apolipoprotein L1 gene (APOL1). Genes control what is inherited from a family, such as eye color or blood type. Variation in APOL1 can cause kidney disease. African Americans, Afro-Caribbeans, Hispanic Blacks, and Africans are more likely to have the APOL1 gene variants that cause kidney disease. APOLLO will test DNA from ki... Read More
Gender:
ALL
Ages:
All
Trial Updated:
02/04/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Kidney Diseases, Kidney Failure, Kidney Disease, Chronic
Register for Updates
Common Factors Group Psychotherapy for General Mental Health Concerns
NCT06614842
Recruiting
The current research will investigate the impact of general psychotherapy using common factors (i.e., techniques and communication skills that are common to all major forms of psychotherapy) to investigate whether mental health professionals can treat a variety of mental health concerns utilizing this general form of psychotherapy as opposed to specific forms of psychotherapy that may require specific trainings or education.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Major Depression, Generalized Anxiety, Stress Disorder, Post Traumatic, Stress, Mental Disorders
Register for Updates
Postoperative Pain Management Following Robotic Assisted Sacrocolpopexy
NCT06309693
Recruiting
In the effort to reduce postoperative opioid use, there has been increasing interest in developing multimodal pain regimens to better manage postoperative pain while minimizing opioid use and their subsequent side effects that can be detrimental to the healing process. Standard of care approaches to better manage postoperative pain include the Enhanced Recovery After Surgery (ERAS) protocol and the use of peripheral and truncal nerve blocks. Truncal nerve blocks are widely used as an additional... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Pelvic Organ Prolapse, Post Operative Pain
Register for Updates
The Impact of a Virtual Magic Trick Training Program
NCT05664841
Recruiting
The proposed project will attempt to confirm the benefits of a structured magic trick training program (MTTP) experience in adolescents with autism. Benefits of participating in a 6-week virtual MTTP will be evaluated using validated assessments to measure social-emotional competencies.
Gender:
ALL
Ages:
Between 11 years and 18 years
Trial Updated:
02/03/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Autism, Pervasive Developmental Disorder
Register for Updates
Curcumin, Resveratrol, and Stinging Nettle as Treatments for GWI
NCT05377242
Recruiting
This project's objective is to identify effective treatments for Gulf War Illness (GWI). The project tests three potential treatments: curcumin, stinging nettle, and resveratrol. The project uses a decentralized clinical trial (DCT) design in which individuals can participate from anywhere in the United States. Recruitment efforts will be designed to obtain a geographically and demographically diverse study sample.
Gender:
ALL
Ages:
45 years and above
Trial Updated:
02/03/2025
Locations: The University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Gulf War Illness
Register for Updates
STROKE STAT (Stroke Severity-based Triage to Accelerate Treatment)
NCT04978480
Recruiting
Acute stroke systems of care should emulate trauma systems which deliver the full range of care to all injured patients by means of organized, coordinated efforts in defined geographic areas. Just as trauma systems have proven ability to save lives of the most severely injured patients, clinicians should have a stroke system able to provide care to patients with the most severe strokes. The most severe type of acute ischemic stroke is due to proximal large vessel occlusion (LVO). Mechanical thro... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Stroke
Register for Updates
A Study to Evaluate the Benefits and Risks of Conversion of Existing Adolescent Kidney Transplant Recipients Aged 12 to <18 Years to a Belatacept-based Immunosuppressive Regimen as Compared to Continuation of a Calcineurin Inhibitor-based Regimen, and Their Adherence to Immunosuppressive Medications
NCT04877288
Recruiting
The purpose of this study is to evaluate the benefits and risks of conversion of existing adolescent kidney allograft recipients aged 12 to less than 18 years of age to a belatacept-based immunosuppressive regimen as compared to continuation of a calcineurin inhibitor-based regimen and their adherence to immunosuppressive medications.
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
02/03/2025
Locations: Local Institution - 0042, Birmingham, Alabama
Conditions: Renal Allograft Recipients
Register for Updates