Alabama is currently home to 1237 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Birmingham, Mobile, Huntsville and Anniston. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
The Impact of a Virtual Magic Trick Training Program
NCT05664841
Recruiting
The proposed project will attempt to confirm the benefits of a structured magic trick training program (MTTP) experience in adolescents with autism. Benefits of participating in a 6-week virtual MTTP will be evaluated using validated assessments to measure social-emotional competencies.
Gender:
ALL
Ages:
Between 11 years and 18 years
Trial Updated:
02/03/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Autism, Pervasive Developmental Disorder
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Curcumin, Resveratrol, and Stinging Nettle as Treatments for GWI
NCT05377242
Recruiting
This project's objective is to identify effective treatments for Gulf War Illness (GWI). The project tests three potential treatments: curcumin, stinging nettle, and resveratrol. The project uses a decentralized clinical trial (DCT) design in which individuals can participate from anywhere in the United States. Recruitment efforts will be designed to obtain a geographically and demographically diverse study sample.
Gender:
ALL
Ages:
45 years and above
Trial Updated:
02/03/2025
Locations: The University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Gulf War Illness
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STROKE STAT (Stroke Severity-based Triage to Accelerate Treatment)
NCT04978480
Recruiting
Acute stroke systems of care should emulate trauma systems which deliver the full range of care to all injured patients by means of organized, coordinated efforts in defined geographic areas. Just as trauma systems have proven ability to save lives of the most severely injured patients, clinicians should have a stroke system able to provide care to patients with the most severe strokes. The most severe type of acute ischemic stroke is due to proximal large vessel occlusion (LVO). Mechanical thro... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Stroke
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Study of Selinexor in Combination with Ruxolitinib in Myelofibrosis
NCT04562389
Recruiting
This is a global, multicenter, 2-part study to evaluate the efficacy and safety of selinexor plus ruxolitinib in JAK inhibitor (JAKi) treatment-naïve myelofibrosis (MF) participants. The study will be conducted in two phases: Phase 1 (open-label) and Phase 3 (double-blind). Phase 1 (enrollment completed) was an open-label evaluation of the safety and recommended Phase 2 dose (RP2D) of selinexor in combination with ruxolitinib and included a dose escalation using a standard 3+3 design (Phase 1a)... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: UAB Division of Hematology/Oncology, Birmingham, Alabama
Conditions: Myelofibrosis
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Study Assessing CLENPIQ As Bowel Preparation for Pediatric Colonoscopy
NCT04113382
Recruiting
Bowel preparation for pediatric colonoscopy.
Gender:
ALL
Ages:
Between 2 years and 8 years
Trial Updated:
02/03/2025
Locations: Ferring Investigational Site, Mobile, Alabama
Conditions: Bowel Preparation
Register for Updates
Nasal Potential Difference (NPD) Protocol in Chronic Rhinosinusitis
NCT02038166
Recruiting
The purpose of this study is to determine if acquired (partial) Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) deficiency contributes substantially to the pathogenic mechanisms underlying Chronic Rhinosinusitis (CRS), creating a localized environment that impairs mucociliary clearance (MCC).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/03/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Rhinosinusitis
Register for Updates
Dose Escalation Trial of Safety, Pharmacokinetic/Pharmacodynamic and Preliminary Clinical Activity of Briquilimab in Adult Patients with Chronic Spontaneous Urticaria (CSU)
NCT06162728
Recruiting
This trial will be performed as a three-part dose escalating clinical trial where Parts 1 is open label and Parts 2 and 3 are randomized, double-blinded, and placebo-controlled. The trial is intended to determine the safety and tolerability and assess the preliminary efficacy of briquilimab in adult participants with chronic spontaneous urticaria (CSU), who remain symptomatic despite treatment with H1 antihistamines and omalizumab. Additionally, pharmacokinetic (PK) properties of briquilimab, a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: Site 118, Birmingham, Alabama
Conditions: Chronic Spontaneous Urticaria
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The Presence of a Therapy Dog Reduces Pain and Anxiety During Pediatric Elbow Pin Removal
NCT05830201
Recruiting
The purpose of this research study is to assess whether the presence of therapy dogs can reduce pain and anxiety in children ages 3 to 10 having pins removed from their elbow.
Gender:
ALL
Ages:
Between 3 years and 10 years
Trial Updated:
01/31/2025
Locations: UAB, Birmingham, Alabama
Conditions: Elbow Injury
Register for Updates
Efficacy and Safety of Iptacopan (LNP023) in Adult Patients With Atypical Hemolytic Uremic Syndrome Naive to Complement Inhibitor Therapy
NCT04889430
Recruiting
The purpose of this Phase 3 study is to determine whether iptacopan (LNP023) is efficacious and safe for the treatment of aHUS in adult patients who are treatment naive to complement inhibitor therapy.
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
01/31/2025
Locations: Uni Of Alabama At Birmingham, Birmingham, Alabama
Conditions: Atypical Hemolytic Uremic Syndrome
Register for Updates
Video Telehealth Exercise Training in Cystic Fibrosis
NCT04680403
Recruiting
The purpose of this research study is to begin an exercise program for patients with a cystic fibrosis (CF) exacerbation.
Gender:
ALL
Ages:
19 years and above
Trial Updated:
01/31/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cystic Fibrosis
Register for Updates
RESTORE: REducing Future FractureS and Improving OuTcOmes of FRagility FracturE
NCT06455085
Recruiting
RESTORE tests whether Augmented-FLS, where patients are contacted by a patient navigator (serving as the liaison) and referred to a bone health provider, is better than Enhanced Usual Care, which includes patient and PCP education and activation. We also aim to determine the influence of age, race, ethnicity, sex, poverty level, geographic region, and timing of entry into the trial after a fracture on the effectiveness of the two strategies.
Gender:
ALL
Ages:
50 years and above
Trial Updated:
01/30/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Osteoporosis, Osteoporotic Fractures
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A Stakeholder-enhanced Intervention to Improve the Decisional Partnership of Chronic Kidney Disease Dyads (IMPART)
NCT06173323
Recruiting
Using a highly innovative methodology, the Multiphase Optimization Strategy (MOST), the purpose of this study is to pilot test, an optimization trial approach to develop and refine the decision partnering skills of persons with stage 4 chronic kidney disease and their caregivers. Using a 2x2x2 full factorial design, 64 dyads (patients and one identified caregiver) will be randomized to receive one or more lay coach-delivered decision partnering training components, based on Pearlin's Stress-Heal... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/29/2025
Locations: Shena Gazaway, Birmingham, Alabama
Conditions: Decision Making, Shared, Family Caregiving, Chronic Kidney Disease
Register for Updates