There are currently 7 active clinical trials seeking participants for Narcolepsy research studies. The states with the highest number of trials for Narcolepsy participants are California, Florida, Ohio and Texas.
Study of MK-6552 in Participants With Narcolepsy Type 1 (MK-6552-004)
NCT06179407
Recruiting
The purpose of this study is to evaluate the safety, efficacy, pharmacokinetics (PK), and pharmacodynamics (PD) of MK-6552 in participants with Narcolepsy Type 1 (NT1). Part 1 will evaluate safety, tolerability, and PK of MK-6552 after administration of ascending doses in a single day to support a dose level decision for Part 2. Part 2 will investigate the PD of MK-6552 after single-day and multiple-day administration. Participants who complete Part 1 and demonstrate that they are able to tolera... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
06/20/2024
Locations: Delta Waves, Inc. ( Site 0008), Colorado Springs, Colorado +4 locations
Conditions: Narcolepsy
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A Switch Study From High-Sodium Oxybate to XYWAV to Evaluate Changes in Blood Pressure in Participants With Narcolepsy
NCT05869773
Recruiting
The aim of this study is to quantify the change in blood pressure when participants with narcolepsy treated with high-sodium oxybate are transitioned to XYWAV, a low-sodium oxybate. The results of this study may provide health care providers (HCPs), patients, and payers with important new information regarding BP changes related to differences in sodium content between available oxybates for the treatment of narcolepsy.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
06/18/2024
Locations: University of Arizona, Tucson, Arizona +50 locations
Conditions: Narcolepsy
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Child and Adolescent Registry for Participants With Narcolepsy
NCT04899947
Recruiting
CATNAP is a patient registry designed to improve the understanding of the natural history of narcolepsy in pediatric patients. Descriptive statistics on disease characteristics will be performed. The study has 16 active clinical sites and a virtual site that widens participation to anywhere in the United States. For more information about the study or to access the Online Patient Enrollment System, visit the CATNAP website: https://catnap.healthie.net/welcome or email catnap@pulseinfoframe.com.... Read More
Gender:
All
Ages:
17 years and below
Trial Updated:
05/14/2024
Locations: Phoenix Children's Hospital, Phoenix, Arizona +24 locations
Conditions: Narcolepsy
Register for Updates
SUNOSI® (Solriamfetol) Pregnancy Registry
NCT06413420
Recruiting
The SUNOSI (solriamfetol) Pregnancy Registry is a prospective, multi-country, observational study to evaluate the safety of solriamfetol exposure during pregnancy in women with a diagnosis of narcolepsy or obstructive sleep apnea (OSA).
Gender:
Female
Ages:
All
Trial Updated:
05/09/2024
Locations: Evidera, a PPD business unit, Morrisville, North Carolina +1 locations
Conditions: Narcolepsy, Obstructive Sleep Apnea, Pregnant Women and Their Offspring
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Ph4 PSG Combined JZP258-407
NCT05875974
Recruiting
This study will assess the safety and efficacy of JZP258 (XYWAV) on sleepiness, polysomnography, and functional outcomes in patients with idiopathic hypersomnia (IH) or narcolepsy.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/29/2024
Locations: Sleep Disorders Center of Alabama, Birmingham, Alabama +27 locations
Conditions: Idiopathic Hypersomnia, Narcolepsy
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WAKIX® (Pitolisant) Pregnancy Registry
NCT05536011
Recruiting
The WAKIX (pitolisant) Pregnancy Registry is a US-based, prospective, observational cohort study designed to evaluate the association between pitolisant exposure during pregnancy and subsequent maternal, fetal, and infant outcomes.
Gender:
Female
Ages:
All
Trial Updated:
01/24/2024
Locations: Evidera (PPD), Morrisville, North Carolina
Conditions: Pregnancy Related, Narcolepsy
Register for Updates
Development and Validation of Pediatric Narcolepsy Patient Reported Outcomes Scale
NCT05373979
Recruiting
The purpose of this study is to test a pediatric narcolepsy patient reported outcomes tool to assess pediatric narcolepsy symptoms and their effect on daily functioning and quality of life. The goal is to develop a clinical survey that can improve the care of pediatric narcolepsy.
Gender:
All
Ages:
Between 9 years and 17 years
Trial Updated:
05/26/2022
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Narcolepsy, Obstructive Sleep Apnea
Register for Updates