A Switch Study From High-Sodium Oxybate to XYWAV to Evaluate Changes in Blood Pressure in Participants With Narcolepsy
NCT05869773
Recruiting
The aim of this study is to quantify the change in blood pressure when participants with narcolepsy treated with high-sodium oxybate are transitioned to XYWAV, a low-sodium oxybate. The results of this study may provide health care providers (HCPs), patients, and payers with important new information regarding BP changes related to differences in sodium content between available oxybates for the treatment of narcolepsy.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
11/17/2023
Locations: Science 37, Culver City, California +45 locations
Conditions: Narcolepsy
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Ph4 PSG Combined JZP258-407
NCT05875974
Recruiting
This study will assess the safety and efficacy of JZP258 (XYWAV) on sleepiness, polysomnography, and functional outcomes in patients with idiopathic hypersomnia (IH) or narcolepsy.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
10/30/2023
Locations: Sleep Disorders Center of Alabama, Birmingham, Alabama +12 locations
Conditions: Idiopathic Hypersomnia, Narcolepsy
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Child and Adolescent Registry for Participants With Narcolepsy
NCT04899947
Recruiting
CATNAP is a patient registry designed to improve the understanding of the natural history of narcolepsy in pediatric patients. Descriptive statistics on disease characteristics will be performed. The study has 16 active clinical sites and a virtual site that widens participation to anywhere in the United States. For more information about the study or to access the Online Patient Enrollment System, visit the CATNAP website: https://catnap.healthie.net/welcome or email catnap@pulseinfoframe.com.... Read More
Gender:
All
Ages:
17 years and below
Trial Updated:
05/16/2023
Locations: Phoenix Children's Hospital, Phoenix, Arizona +24 locations
Conditions: Narcolepsy
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A Study to Assess the Efficacy and Safety of AXS-12 (Reboxetine) in Patients With Narcolepsy
NCT05059223
Recruiting
This study is a multi-center, double-blind, placebo-controlled, randomized Phase 3 trial to assess the safety and efficacy of AXS-12 in narcoleptic subjects with cataplexy and excessive daytime sleepiness (EDS).
Gender:
All
Ages:
Between 15 years and 75 years
Trial Updated:
03/03/2023
Locations: Clinical Research Site, Alabaster, Alabama +46 locations
Conditions: Narcolepsy, Cataplexy, Excessive Daytime Sleepiness
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The Nuvigil and Provigil Pregnancy Registry
NCT01792583
Recruiting
The primary objective of the Nuvigil/Provigil Pregnancy Registry is to characterize the pregnancy and fetal outcomes associated with Nuvigil and Provigil exposure during pregnancy.
Gender:
Female
Ages:
All
Trial Updated:
12/13/2022
Locations: Teva Pregnancy Registry, West Chester, Pennsylvania
Conditions: Narcolepsy, Obstructive Sleep Apnea, Shift Work Sleep Disorder
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WAKIX® (Pitolisant) Pregnancy Registry
NCT05536011
Recruiting
The WAKIX (pitolisant) Pregnancy Registry is a US-based, prospective, observational cohort study designed to evaluate the association between pitolisant exposure during pregnancy and subsequent maternal, fetal, and infant outcomes.
Gender:
Female
Ages:
All
Trial Updated:
09/07/2022
Locations: Evidera (PPD), Morrisville, North Carolina
Conditions: Pregnancy Related, Narcolepsy
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Development and Validation of Pediatric Narcolepsy Patient Reported Outcomes Scale
NCT05373979
Recruiting
The purpose of this study is to test a pediatric narcolepsy patient reported outcomes tool to assess pediatric narcolepsy symptoms and their effect on daily functioning and quality of life. The goal is to develop a clinical survey that can improve the care of pediatric narcolepsy.
Gender:
All
Ages:
Between 9 years and 17 years
Trial Updated:
05/26/2022
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Narcolepsy, Obstructive Sleep Apnea
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