There are currently 167 active clinical trials seeking participants for Lung Cancer research studies. The states with the highest number of trials for Lung Cancer participants are Ohio, California, Illinois and Michigan.
Testing the Engaged Approach to Lung Cancer Screening
NCT06327074
Recruiting
The goal of this study is to assess feasibility and acceptability of the Engaged Approach to Lung Cancer Screening (EA-LCS) in diverse lung cancer screening (LCS) programs operating in a variety of geographic regions across Colorado and the US.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/15/2025
Locations: University of Colorado Hospital, Denver, Colorado
Conditions: Lung Cancer
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Ovarian-Sparing Adaptive Radiotherapy in Young Adult Women
NCT06904365
Recruiting
Female patients with early onset (\<50 years old) pelvic malignancies such as uterine and rectal cancers are rising in incidence, which often requires pelvic radiation; many of these patients are premenopausal and at a high risk of premature ovarian failure from radiotherapy. Premature ovarian failure carries significant cardiac, musculoskeletal, sexual, and psychosocial morbidity. Ovarian transposition carries variable success rates, is not readily accessible to the general population, and can... Read More
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
04/09/2025
Locations: Washington University School of Medicine, Saint Louis, Missouri
Conditions: Uterine Cancer, Rectal Cancer, Colon Cancer, Breast Cancer, Lung Cancer, Sarcoma, Cervix Cancer, Head and Neck Cancer, Anal Cancer, Liver Cancer, Gastric Cancer, Bladder Cancer
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Dose Attenuated Chemotherapy in Compromised Patients With Lung Cancer
NCT05800587
Recruiting
This is an open-label, non-randomized, single-center, phase II study to evaluate the efficacy, toxicity and, tolerability of pre-specified dose attenuated chemotherapy regimens in lung cancer patients with comorbidities.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/03/2025
Locations: Fox Chase Cancer Center, Philadelphia, Pennsylvania
Conditions: Lung Cancer, Small-cell Lung Cancer, Non Small Cell Lung Cancer
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Feasibility Study to Treat Lung Cancer With the Permanently Implantable LDR CivaSheet®
NCT03290534
Recruiting
This is a feasibility study to determine the usefulness of a brachytherapy device that utilizes active components (palladium-103) of standard devices in a novel configuration, which may benefit lung cancer patients by reducing the radiation dose to critical structures, such as the heart wall, while giving a therapeutic dose to diseased tissue, such as at a surgical margin.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/02/2025
Locations: NYU Langone Health, New York, New York
Conditions: Lung Cancer, Lung Cancer Stage I, Lung Cancer Stage II
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Confocal Laser Endomicroscopy VERification
NCT06079970
Recruiting
The goal of this multi-center randomized clinical trial is to evaluate the added value of needle based confocal laser endomicroscopy (nCLE)-imaging to regular diagnostic bronchoscopic peripheral lung lesion analysis on the diagnostic yield in patients with peripheral pulmonary nodules suspect for malignancy. The main question\[s\] it aims to answer are: To determine if the addition of nCLE-imaging to conventional diagnostic bronchoscopic peripheral lung lesion analysis results in an improved d... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/02/2025
Locations: Montefiore Medical Center, New York, New York +6 locations
Conditions: Lung Cancer, Lung Neoplasm Malignant, Carcinoma, Non-Small-Cell Lung, Neoplasm of Lung
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Novel Lung Imaging in Adults Undergoing Radiation Therapy to Assess for Radiation Pneumonitis
NCT02735746
Recruiting
The purpose of this study is to to compare lung function data generated by applying High Fidelity Functional Lung Imaging (HFFLI) software to 4D CT, cone beam CT, and fluoroscopic images of the lungs breathing to determine whether different modalities of imaging provide similar data on lung movement and function. HFFLI may detect changes in lung function in patients undergoing External Beam Radiotherapy for cancer.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/01/2025
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Lung Cancer, Breast Cancer, Mediastinum Lesion, Radiation Pneumonitis
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Metabolic Biomarkers in Thoracic Cancers
NCT02095808
Recruiting
The purpose of this research study is to develop a method of using magnetic resonance imaging (MRI) to evaluate lung tumors and other thoracic malignancies. An MRI is a scanning device that uses magnets to make images (pictures) of the body. This study is being done to determine what series of reactions (metabolic pathways) pulmonary nodules use as they burn sugar as fuel for growth. The manner in which the tumor burns (metabolizes) sugar for fuel is being investigated by using a natural, slight... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: University of Texas Southwestern Medical Center, Dallas, Texas
Conditions: Lung Cancer
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Collection of Sputum and Labeling for Lung Cancer
NCT03457415
Recruiting
The primary objective of this study is to compare Assay results to diagnoses determined by currently accepted standards for lung cancer detection. This will be accomplished by analysis of sputum samples from three cohorts including healthy Participants, high risk Participants, and cancer patient Participants using the Assay as developed in accordance with findings of bioAffinity protocol BA-001 to confirm assay results. Adjustments will be made as necessary to finalize Assay design for clinical... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
03/26/2025
Locations: Atlantic Respiratory Institute, Summit, New Jersey +2 locations
Conditions: Lung Cancer
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KK-LC-1 TCR-T Cell Therapy for Gastric, Breast, Cervical, and Lung Cancer
NCT05483491
Recruiting
This is a phase I clinical trial to determine the maximum tolerated dose (MTD) of KK-LC-1 TCR-T cells for the treatment of metastatic cancers that express KK-LC-1. Participants will receive a conditioning regimen, KK-LC-1 TCR-T cells, and aldesleukin. The safety profile and clinical response to treatment will be determined.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/25/2025
Locations: Rutgers Cancer Institute of New Jersey, New Brunswick, New Jersey +1 locations
Conditions: Gastric Cancer, Breast Cancer, Cervical Cancer, Lung Cancer
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Centralized Screening Unit (CSU) at Montefiore-Einstein
NCT06284408
Recruiting
This study proposes to increase Lung-cancer screening (LCS) in the Bronx, New York. Despite strong evidence that Lung-cancer screening (LCS) can reduce Lung cancer (LCa) deaths, low-dose computed tomography (LDCT) referral rates by clinicians are very low and there is poor adherence with LCS by patients. Both provider and patient barriers may be amenable to systemic improvements in support, coordination and infrastructure for screening. The investigator team hypothesizes that the implementation... Read More
Gender:
ALL
Ages:
Between 50 years and 77 years
Trial Updated:
03/24/2025
Locations: Montefiore Medical Center's New York City Research and Improvement Networking Group (NYC RING), Bronx, New York
Conditions: Lung Cancer
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COPD Care Pathway Among Patients With Cancer
NCT05984680
Recruiting
This study gathers information for the development of a COPD care pathway for patients with cancer that reduces the treatment burden of patients, implements critical components of COPD care, and overcomes common barriers to COPD care in the community oncology clinic.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/24/2025
Locations: Wake Forest Baptist Comprehensive Cancer Center, Winston-Salem, North Carolina
Conditions: Chronic Obstructive Pulmonary Disease, Lung Cancer, Head and Neck Cancer
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4D-MRI for Precision Medicine
NCT04657042
Recruiting
The purpose of this study is to develop new ways to make medical images of the lungs and liver of adults using a technique called four-dimensional magnetic resonance imaging (4D-MRI). This technique produces three-dimensional movies of the inside of the chest and abdomen while the patient is breathing. (The fourth dimension is time!) This new way of medical imaging is being developed to help cancer patients undergoing radiation therapy. Radiation therapy is used to treat cancerous tumors. For r... Read More
Gender:
ALL
Ages:
Between 18 years and 82 years
Trial Updated:
03/19/2025
Locations: University of Virginia, Charlottesville, Virginia
Conditions: Healthy Volunteers, Liver Cancer, Lung Cancer
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