GLP-1 Medications for Weight Loss Now Available!

There are currently 32 active clinical trials seeking participants for Weight Loss research studies. The states with the highest number of trials for Weight Loss participants are California, Texas, Florida and North Carolina.
Optimizing an Extended Care Intervention to Promote Weight Loss Maintenance
Recruiting
The purpose of this study is to find out what combination of components, if any, offers the best support for keeping weight off after someone loses weight. Long term weight loss maintenance is a challenge for many people who lose weight. There are many strategies, or components, people may use to avoid regain, but investigators do not know if there is a best, or optimal, combination of such components that can be done without adding a lot of cost or other burdens for people. * The primary goal... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/02/2025
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Obesity Prevention, Weight Change, Weight Loss, Weight Loss Maintenance
Small Intestinal Bacterial Overgrowth (SIBO) in Pancreatic Adenocarcinoma (PDAC)
Recruiting
The purpose of this study is to prospectively analyze the prevalence of SIBO in patients with Pancreatic adenocarcinoma (PDAC) and understand its association with weight loss and pancreatic resection status. Each patient will be tested for SIBO using Lactulose Hydrogen Breath Test. 100 patients with diagnosed pancreatic adenocarcinoma and clinically diagnosed weight loss will be enrolled in this study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/21/2025
Locations: Cedars-Sinai Medical Center, Los Angeles, California
Conditions: Pancreatic Adenocarcinoma, Weight Loss
Endoscopic Bariatric Therapies (EBTs): A Retrospective and Prospective Multicenter Registry
Recruiting
The purpose of this registry study is to collect data through medical chart review and in patient visits on the efficacy and safety of various Endoscopic Bariatric therapies (EBTs). This is a retrospective and prospective, observational, medical chart review study for at least 6 standard of care visits up to 1 years after a subject consents for study participation.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
05/20/2025
Locations: Weill Cornell Medicine, New York, New York
Conditions: Obesity, Weight Loss, Gastro Esophageal Reflux, Bariatric Surgery Candidate
Metabolic Health, Bones and Nuts During Weight Loss in Adults
Recruiting
The aging population is rapidly increasing, and it is important to identify dietary factors that can prevent disease and promote health in this group. Legumes, such as peanuts, are a plant-based food high in protein and unsaturated fat making this a healthy choice but are not consumed frequently enough in older adults. Studies have shown that regular nut consumption is associated with lower adiposity and reduced weight gain, and several dietary pattern studies indicate that nuts and legumes are... Read More
Gender:
ALL
Ages:
Between 50 years and 75 years
Trial Updated:
04/21/2025
Locations: Rutgers University - NJ Inst Food Nutrition & Health, New Brunswick, New Jersey
Conditions: Weight Loss, Bone Density, Obesity and Overweight
Dyad Plus Effectiveness/Feasibility
Recruiting
The purpose of this research is to determine the effectiveness of a coordinated program (Dyad Plus) that would help to facilitate self-monitoring, positive communication, joint problem solving, and social support to increase physical activity, healthy eating, and weight loss. Participants of the Brenner FIT (Families In Training) pediatric weight management program and their parent/guardian will co-enroll in weight loss programs. Parents/guardians will receive the components of By Design Essenti... Read More
Gender:
ALL
Ages:
Between 13 years and 65 years
Trial Updated:
03/28/2025
Locations: Wake Forest Baptist Medical Center, Winston-Salem, North Carolina
Conditions: Weight Loss, Pediatric Obesity, Overweight Adolescents, Parent-Child Relations, Family and Household
FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)
Recruiting
The goal of this clinical trial is to learn the best combination of family components that yields optimal weight loss among Black adults. The main question it aims to answer is: What combination of four family components in combination with a standard behavioral weight loss program yields optimal weight loss among Black adults? Researchers will compare different combinations of family skills components (communication content, cohesion content, number of sessions, and mode of delivery) to see th... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/25/2025
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Conditions: Obesity and Overweight, Diabetes Mellitus, Weight Loss, Behavior Change
VK2735 for Weight Management Phase 2 (Venture Oral Dosing)
Recruiting
This is a phase 2, 13-week randomized, double-blind, placebo-controlled, parallel arm dose-finding study that will evaluate the safety, tolerability, weight loss efficacy, pharmacodynamic effects, and pharmacokinetics of VK2735 Oral Formulation in adults who are obese (BMI ≥30 kg/m2) or who are overweight (BMI ≥27 kg/m2) with at least one weight-related co-morbid condition. VK2735 or matched placebo will be administered once daily.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: Viking Clinical Site #111, Peoria, Arizona +14 locations
Conditions: Weight Loss
Adipocyte-Derived Extracellular Vesicles, Weight Loss, and Endothelial Function
Recruiting
Changes in adipose tissue biology are now recognized as a key factor underlying the increased risk of metabolic and cardiovascular disease with obesity. Clinical interest in adipocyte-derived extracellular vesicles (Ad-EVs) has intensified due to their potential as circulating biomarkers of adipose tissue health and systemic messengers, regulators and mediators of cardiometabolic health and disease with obesity. The investigators hypothesize that elevated Ad-EVs in adults with obesity will be n... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
01/09/2025
Locations: University of Colorado Boulder Clinical and Translational Research Center (CTRC), Boulder, Colorado
Conditions: Obesity, Weight Loss
iAmHealthy Parents First: A Televideo Parent and Child Obesity Program for Rural Families
Recruiting
The purpose of this study is to assess whether providing a parent-only group program before providing a parent and child group program works better than the parent and child group program alone.
Gender:
ALL
Ages:
6 years and above
Trial Updated:
12/20/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Weight Loss, Pediatric Obesity
Choosing Healthy Activities and Lifestyle Management Through Portal Support
Recruiting
The study aims to randomize 250 participants to 1 of 2 arms: a.) an Active Intervention Group (based on the Look AHEAD\* ILI) or b.) a Comparison Group (based on the Look AHEAD DSE Comparison group) to test the hypothesis that a multicomponent, multilevel behavioral weight loss intervention (Active Intervention Group) adapted for underserved groups and delivered through Health Information Technology (Health IT) tools via the Electronic Health Record (EHR) patient portal, will result in significa... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
12/10/2024
Locations: University of Tennessee Health Science Center / Department of Preventive Medicine, Memphis, Tennessee
Conditions: Weight Loss, Overweight and Obesity, Behavior, Health
International Weight Control Registry
Recruiting
The IWCR is a global scientific study aimed at better understanding the opportunities and barriers for reducing the prevalence of obesity by collecting information from people who have experience with weight management in their everyday lives. The investigators seek to gather information on a wide range of weight management experiences, ranging from weight loss and weight loss maintenance to weight gain and inability to lose weight.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/03/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama +6 locations
Conditions: Weight Loss, Overweight, Obesity
Use of Continuous Glucose Monitoring in Non-Diabetic Population to Compliment Signos Mobile Health Platform
Recruiting
Metabolic syndrome and resulting downstream health effects remains a growing health concern. In published trials, the use of continuous glucose monitoring (CGM) assists behavioral changes efforts, leading to improved adherence and results from diet and exercise changes in individuals with obesity, pre-diabetes and diabetes. Mobile health (mHealth) platforms provide satisfactory, easy-to-use tools that help participants in the pursuit of weight change goals. We hypothesize that the use of CGM dat... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: Signos, Palo Alto, California
Conditions: Weight Loss, Metabolic Syndrome, Pre-diabetes, Central Obesity, Glucose Intolerance, Metabolic Glucose Disorders