GLP-1 Medications for Weight Loss Now Available!

There are currently 28 active clinical trials seeking participants for Weight Loss research studies. The states with the highest number of trials for Weight Loss participants are California, North Carolina, Texas and Pennsylvania.
Effects of Brain Stimulation on Food Intake and Behavioral Weight Loss Treatment
NCT00739362
Recruiting
This study will determine whether electrical stimulation of an area of the brain called the dorsolateral prefrontal cortex, which is important in determining the feeling of fullness after eating, affects how much food a person eats and weight loss over 4 weeks. It will also compare weight changes in people who attend weight loss counseling sessions and those who do not over this period of time. Obese, non-diabetic people between 18 and 60 years of age who are in good health and who live in the... Read More
Gender:
ALL
Ages:
Between 18 years and 60 years
Trial Updated:
05/02/2025
Locations: NIDDK, Phoenix, Phoenix, Arizona
Conditions: Electric Stimulation Therapy, Obesity, Weight Loss, Eating
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Metabolic Health, Bones and Nuts During Weight Loss in Adults
NCT06949280
Recruiting
The aging population is rapidly increasing, and it is important to identify dietary factors that can prevent disease and promote health in this group. Legumes, such as peanuts, are a plant-based food high in protein and unsaturated fat making this a healthy choice but are not consumed frequently enough in older adults. Studies have shown that regular nut consumption is associated with lower adiposity and reduced weight gain, and several dietary pattern studies indicate that nuts and legumes are... Read More
Gender:
ALL
Ages:
Between 50 years and 75 years
Trial Updated:
04/21/2025
Locations: Rutgers University - NJ Inst Food Nutrition & Health, New Brunswick, New Jersey
Conditions: Weight Loss, Bone Density, Obesity and Overweight
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Food is Medicine: Pilot Study
NCT06797453
Recruiting
The goal of this study is to determine whether shared medical visits also called "group visits" would be beneficial for patients who are under weight management care. As part of this study, participants will be asked to complete a survey to give the study team a better idea of their current health conditions and if this study will be good fit for them. Once the survey has been completed, participants will then be randomly assigned to one of two groups. Group one will include participation in sh... Read More
Gender:
ALL
Ages:
Between 18 years and 90 years
Trial Updated:
04/15/2025
Locations: Duke University, Durham, North Carolina
Conditions: Weight Loss
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PROFAST Intervention in Precursor Multiple Myeloma
NCT05565638
Recruiting
This is a 4-month randomized trial of a prolonged nightly fasting intervention (PROFAST) in 40 overweight and obese individuals with monoclonal gammopathy of undetermined significance (MGUS), smoldering multiple myeloma (SMM), and smoldering waldenstrom macroglobulinemia (SWM). The purpose of this study is to understand if fasting for a prolonged period of time during the nighttime hours is a strategy to prevent overweight and obese individuals from developing blood cancer. Participants will be... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/14/2025
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Cancer Prevention, Weight Loss, Smoldering Waldenstrom Macroglobulinemia(WM), MGUS, Fasting, Multiple Myeloma
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Dyad Plus Effectiveness/Feasibility
NCT04036331
Recruiting
The purpose of this research is to determine the effectiveness of a coordinated program (Dyad Plus) that would help to facilitate self-monitoring, positive communication, joint problem solving, and social support to increase physical activity, healthy eating, and weight loss. Participants of the Brenner FIT (Families In Training) pediatric weight management program and their parent/guardian will co-enroll in weight loss programs. Parents/guardians will receive the components of By Design Essenti... Read More
Gender:
ALL
Ages:
Between 13 years and 65 years
Trial Updated:
03/28/2025
Locations: Wake Forest Baptist Medical Center, Winston-Salem, North Carolina
Conditions: Weight Loss, Pediatric Obesity, Overweight Adolescents, Parent-Child Relations, Family and Household
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Time-restricted Eating Versus Daily Continuous Calorie Restriction on Body Weight and Colorectal Cancer Risk Markers
NCT05114798
Recruiting
Approximately 42% of American adults are obese, and this condition is strongly related to the development of colorectal cancer. Innovative lifestyle strategies to treat obesity and reduce colorectal cancer risk are critically needed. This research will demonstrate that time-restricted eating, a type of intermittent fasting, is an effective therapy to help obese individuals reduce and control their body weight and prevent the development of colorectal cancer.
Gender:
ALL
Ages:
Between 45 years and 70 years
Trial Updated:
03/05/2025
Locations: University of Illinois at Chicago, Chicago, Illinois
Conditions: Time Restricted Eating, Obesity, Weight Loss, Colorectal Cancer
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Stay In Treatment for Pediatric Weight Management
NCT04364282
Recruiting
Attrition from pediatric weight management programs is unacceptably high, with dropout ranging from 27-73%. This project will utilize a model that predicts dropout from treatment, increasing its power and accuracy through a multi-site observational study. This will result in a powerful tool that will be used to decrease attrition from pediatric weight management, with the potential for widespread dissemination to improve treatment outcomes.
Gender:
ALL
Ages:
7 years and above
Trial Updated:
02/26/2025
Locations: Children's Mercy Hospital, Kansas City, Missouri +1 locations
Conditions: Pediatric Obesity, Attrition, Family Research, Weight Loss
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FAMily-centered WEight Loss for Black Adults (FAM WEL B-ing)
NCT06724406
Recruiting
The goal of this clinical trial is to learn the best combination of family components that yields optimal weight loss among Black adults. The main question it aims to answer is: What combination of four family components in combination with a standard behavioral weight loss program yields optimal weight loss among Black adults? Researchers will compare different combinations of family skills components (communication content, cohesion content, number of sessions, and mode of delivery) to see th... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/25/2025
Locations: University of North Carolina at Chapel Hill, Chapel Hill, North Carolina
Conditions: Obesity and Overweight, Diabetes Mellitus, Weight Loss, Behavior Change
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VK2735 for Weight Management Phase 2 (Venture Oral Dosing)
NCT06828055
Recruiting
This is a phase 2, 13-week randomized, double-blind, placebo-controlled, parallel arm dose-finding study that will evaluate the safety, tolerability, weight loss efficacy, pharmacodynamic effects, and pharmacokinetics of VK2735 Oral Formulation in adults who are obese (BMI ≥30 kg/m2) or who are overweight (BMI ≥27 kg/m2) with at least one weight-related co-morbid condition. VK2735 or matched placebo will be administered once daily.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: Viking Clinical Site #111, Peoria, Arizona +14 locations
Conditions: Weight Loss
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Adipocyte-Derived Extracellular Vesicles, Weight Loss, and Endothelial Function
NCT06776081
Recruiting
Changes in adipose tissue biology are now recognized as a key factor underlying the increased risk of metabolic and cardiovascular disease with obesity. Clinical interest in adipocyte-derived extracellular vesicles (Ad-EVs) has intensified due to their potential as circulating biomarkers of adipose tissue health and systemic messengers, regulators and mediators of cardiometabolic health and disease with obesity. The investigators hypothesize that elevated Ad-EVs in adults with obesity will be n... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
01/09/2025
Locations: University of Colorado Boulder Clinical and Translational Research Center (CTRC), Boulder, Colorado
Conditions: Obesity, Weight Loss
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iAmHealthy Parents First: A Televideo Parent and Child Obesity Program for Rural Families
NCT05612971
Recruiting
The purpose of this study is to assess whether providing a parent-only group program before providing a parent and child group program works better than the parent and child group program alone.
Gender:
ALL
Ages:
6 years and above
Trial Updated:
12/20/2024
Locations: University of Kansas Medical Center, Kansas City, Kansas
Conditions: Weight Loss, Pediatric Obesity
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Choosing Healthy Activities and Lifestyle Management Through Portal Support
NCT05410353
Recruiting
The study aims to randomize 250 participants to 1 of 2 arms: a.) an Active Intervention Group (based on the Look AHEAD\* ILI) or b.) a Comparison Group (based on the Look AHEAD DSE Comparison group) to test the hypothesis that a multicomponent, multilevel behavioral weight loss intervention (Active Intervention Group) adapted for underserved groups and delivered through Health Information Technology (Health IT) tools via the Electronic Health Record (EHR) patient portal, will result in significa... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
12/10/2024
Locations: University of Tennessee Health Science Center / Department of Preventive Medicine, Memphis, Tennessee
Conditions: Weight Loss, Overweight and Obesity, Behavior, Health
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