District Of Columbia is currently home to 862 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Washington, Washington, D.C., Washington DC and Washington, Dc. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Protocol CAUSE-03 / CHEETAH
NCT06136091
Recruiting
This is a one-year longitudinal, observational study of 250 urban children and adolescents with asthma and 60 without asthma, ages 6-17 years old. Participants with asthma will require daily controller therapy with inhaled corticosteroids ICS (at least Step 2 therapy). Those without asthma cannot have used asthma medications in the year prior to enrollment and cannot demonstrate bronchodilator reversibility at baseline. Phenotypic characteristics will be established at baseline, and the partici... Read More
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
05/09/2025
Locations: Children's National Medical Center: Children's Research Institute, Washington, District of Columbia
Conditions: Asthma
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Testing the Effect of the Broccoli Seed and Sprout Extract, Avmacol ES, on the Cancer Causing Substances of Tobacco in Heavy Smokers
NCT05121051
Recruiting
This phase II trial tests whether broccoli seed and sprout extract works to break down cancer causing substances of tobacco in heavy smokers. Smokers are at increased risk for developing lung, head and neck, and other cancers. Broccoli seed and sprout extract may help break down and remove toxic substances caused by tobacco use and possibly produce substances that may protect cells from tobacco smoke-induced damage in current smokers.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/09/2025
Locations: George Washington University Medical Center, Washington, District of Columbia
Conditions: Cigarette Smoking-Related Carcinoma
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BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)
NCT04982393
Recruiting
The purpose of this study is to describe the natural history and progression of patients diagnosed with PH1, and to characterize the long-term real-world safety and effectiveness of lumasiran.
Gender:
ALL
Ages:
All
Trial Updated:
05/09/2025
Locations: Clinical Trial Site, Washington, District of Columbia
Conditions: Primary Hyperoxaluria Type 1
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Mosaic Trial for Stem Cell Transplant Recipients
NCT06960993
Recruiting
The goal of this clinical trial is to learn if using an intervention website (Mosaic) improves selected patient-reported outcomes in adult blood cancer patients undergoing allogeneic or autologous stem cell transplant, compared to using an educational website (control group). Patients will be recruited prior to their scheduled transplant, then randomized to use one of these two study websites throughout the study. They will complete five assessments during the study: one before transplant (basel... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/08/2025
Locations: Georgetown University School of Medicine, Washington, District of Columbia
Conditions: Hematologic Malignancy, Stem Cell Transplant, Bone Marrow Transplant, Leukemia, Lymphoma, Multiple Myeloma, Myelodysplastic Syndromes
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The Percutaneous Transmural Arterial Bypass -1 Study (Post Approval Registry)
NCT06315023
Recruiting
The purpose of this post-market surveillance study will be to evaluate the real-world use of the DETOUR System in treated patients with symptomatic femoropopliteal lesions from 200 mm to 460 mm in length with chronic total occlusions (100 mm to 425 mm) or diffuse stenosis \> 70% who may be considered suboptimal candidates for surgical or alternative endovascular treatments.
Gender:
ALL
Ages:
All
Trial Updated:
05/08/2025
Locations: Medstar Washington Hospital Center, Washington, District of Columbia
Conditions: Peripheral Arterial Disease, Symptomatic Femoropopliteal Lesions
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Pembrolizumab and Lenvatinib in Advanced Cervical Cancer
NCT04865887
Recruiting
This is a phase II trial of combination therapy of pembrolizumab and lenvatinib in patients with locally advanced or metastatic cervical cancer that had failed first line of therapy. The hypothesis is the combination of lenvatinib and pembrolizumab will overcome vascular endothelial growth factor (VEGF)-mediated immunosuppression to enhance the response of patients with locally advanced or metastatic cervical cancer.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/08/2025
Locations: MedStar Georgetown University Hospital, Washington, District of Columbia
Conditions: Cervical Cancer, Metastatic Cervical Cancer
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The Mechanistic Biology of Primary Immunodeficiency Disorders
NCT03394053
Recruiting
Background: Primary immunodeficiency disorders, or PIDs, are diseases that weaken the immune system. This makes it easier for a person to get sick. Some PIDs are mild and may not be diagnosed until later in life. Other kinds are severe and can be identified shortly after birth. Researchers want to learn more about PIDs by comparing data from relatives and healthy volunteers to people with a PID. Objective: To learn more about PIDs, including their genetic causes. Eligibility: People ages 0... Read More
Gender:
ALL
Ages:
Between 1 day and 75 years
Trial Updated:
05/08/2025
Locations: Children's National Health System (CNHS), Washington, District of Columbia
Conditions: Primary Immunodeficiency Disorders
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Social Risk Factors and Discrimination in Cancer Survivorship
NCT05301114
Recruiting
The objective of the proposed study is to scale social risk factor screening and referral for cancer survivors and to solidify information exchange between clinical and community settings in order to improve survivor health and well-being. This will be completed through three primary aims: 1) To ascertain workflow and map community resources needed to facilitate social risk factor screening and referral for breast and prostate cancer survivors in Washington, District of Columbia. 2) To determine... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2025
Locations: MedStar Washington Hospital Center, Washington, District of Columbia
Conditions: Social Determinants of Health, Breast Cancer, Prostate Cancer, Health Equity, Disparities
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Intravesical LGG VS Saline Bladder Wash RCT
NCT05230511
Recruiting
This is the first ever comparative effectiveness study of an antibiotic-sparing novel self-management intervention to prevent complicated urinary tract infection (UTI).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2025
Locations: MedStar National Rehabilitation Hospital, Washington, District of Columbia
Conditions: Spinal Cord Injuries, Neurogenic Bladder
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A Study to Learn About the Safety of Litifilimab (BIIB059) Injections and Whether They Can Improve Symptoms of Adult Participants Who Have Systemic Lupus Erythematosus
NCT04895241
Recruiting
In this study, researchers will learn more about a study drug called litifilimab (BIIB059) in participants with systemic lupus erythematosus (SLE). The study will focus on participants who have active disease and are already taking standard of care medications. These may include antimalarials, steroids, and immunosuppressants. The main objective of the study is to learn about the effect litifilimab has on lowering the activity of the disease. The main question researchers want to answer is: -... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/07/2025
Locations: Georgetown University Hospital-Medstar, Washington, District of Columbia
Conditions: Lupus Erythematosus, Systemic
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Lu AF28996 in Participants With Parkinson's Disease (PD)
NCT04291859
Recruiting
The purpose of this study is to investigate the safety of Lu AF28996, how well it is tolerated and what the body does to the drug in participants with Parkinson's disease.
Gender:
ALL
Ages:
Between 35 years and 85 years
Trial Updated:
05/07/2025
Locations: Georgetown University, Washington, District of Columbia
Conditions: Parkinson Disease
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An Observational Research Study to Uncover Subtypes of Cancer Cachexia
NCT06073431
Recruiting
This study evaluates cancer-related weight and muscle mass loss, symptoms, and physical function (cachexia) in patients undergoing treatment for colorectal, lung, or pancreatic cancer that cannot be removed by surgery (unresectable). Patients with these cancer types are at risk for developing cancer cachexia (CC), which is defined as weight loss, muscle loss, and fat loss due to cancer. CC has been associated with reduced physical performance, impaired quality of life, and poorer survival. Many... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/06/2025
Locations: MedStar Georgetown University Hospital, Washington, District of Columbia
Conditions: Advanced Colorectal Carcinoma, Advanced Lung Non-Small Cell Carcinoma, Advanced Pancreatic Adenocarcinoma, Stage IV Colorectal Cancer AJCC v8, Stage IV Lung Cancer AJCC v8, Stage IV Pancreatic Cancer AJCC v8, Unresectable Colorectal Carcinoma, Unresectable Lung Non-Small Cell Carcinoma, Unresectable Pancreatic Adenocarcinoma
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