District Of Columbia is currently home to 920 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Washington, Washington, D.C., Washington DC and Washington, Dc. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study of the Efficacy and Safety of Belimumab in Adults With Systemic Sclerosis Associated Interstitial Lung Disease
NCT05878717
Recruiting
This study investigates the efficacy and safety of belimumab compared to placebo, in addition to standard therapy, for the treatment of participants with systemic sclerosis associated interstitial lung disease (SSc-ILD). The study will evaluate the effect of belimumab treatment on lung function as well as on extra-pulmonary disease manifestations, including skin thickening and general symptoms, such as fatigue, that impact quality of life (QoL).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/03/2024
Locations: GSK Investigational Site, Washington, District of Columbia
Conditions: Systemic Sclerosis Associated Interstitial Lung Disease, Scleroderma, Systemic
Register for Updates
Texts for Diabetes Control Among Homeless Persons
NCT05616026
Recruiting
This mixed method study includes a Randomized Controlled Trial (RCT) and qualitative methods to assess the impact of a SMS text strategy in diabetes control among persons who experience homelessness.
Gender:
All
Ages:
21 years and above
Trial Updated:
01/02/2024
Locations: George Washington University, Washington, District of Columbia
Conditions: Diabetes Mellitus
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Efficacy of the COronary SInus Reducer in Patients With Refractory Angina II
NCT05102019
Recruiting
To demonstrate the safety and effectiveness of the Reducer system for treatment of patients with refractory angina pectoris treated with maximally tolerated guideline-directed medical therapy who demonstrate objective evidence of reversible myocardial ischemia in the distribution of the left coronary artery and who are deemed unsuitable for revascularization. A non-randomized single-arm will further assess the safety and effectiveness of the Neovasc Reducer System in selected subjects with rever... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/02/2024
Locations: MedStar Cardiovascular Research Network, Washington, District of Columbia
Conditions: Refractory Angina
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A Study of Targeted Agents for Patients With Recurrent or Persistent Endometrial Cancer
NCT04486352
Recruiting
This is a Phase IB/II multi-cohort study designed to evaluate the efficacy and safety of targeted agents with or without cancer immune checkpoint therapy with atezolizumab in participant with recurrent and/or persistent endometrial cancer. The main protocol provides a platform for genomic screening with homogeneous basic eligibility criteria in order to direct study participants into biomarker-matched study cohorts consisting of testing targeted agents.
Gender:
Female
Ages:
18 years and above
Trial Updated:
12/22/2023
Locations: Medstar Georgetown Cancer Institute, Washington, District of Columbia
Conditions: Endometrial Cancer
Register for Updates
HIV Antigen-specific T-cells Targeting Conserved Epitopes (HST-NEETs) BMTCTN1903
NCT04975698
Recruiting
This is a Phase II multi-center trial single arm trial of autologous transplantation (ASCT) followed by administration of HST-NEETs for treatment of HIV associated lymphoma
Gender:
All
Ages:
15 years and above
Trial Updated:
12/21/2023
Locations: Georgetown, Washington, District of Columbia
Conditions: HIV Associated Lymphoma
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Study to Evaluate NBI-921352 as Adjunctive Therapy in Subjects With SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE)
NCT04873869
Recruiting
The objective of this study is to assess the efficacy, safety, and pharmacokinetics of NBI-921352 as adjunctive therapy for seizures in subjects with SCN8A Developmental and Epileptic Encephalopathy Syndrome (SCN8A-DEE).
Gender:
All
Ages:
Between 2 years and 21 years
Trial Updated:
12/21/2023
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: SCN8A Developmental and Epileptic Encephalopathy Syndrome
Register for Updates
A Study to Evaluate DAY101 in Pediatric and Young Adult Patients With Relapsed or Progressive Low-Grade Glioma and Advance Solid Tumors
NCT04775485
Recruiting
FIREFLY-1 is an ongoing, Phase 2, multi center, open-label study to evaluate the safety and efficacy of oral pan-RAF inhibitor DAY101 in pediatric, adolescent, and young adult patients with recurrent or progressive low-grade glioma or an advanced solid tumor harboring a known RAF alteration.
Gender:
All
Ages:
Between 6 months and 25 years
Trial Updated:
12/21/2023
Locations: Children's National Medical Center, Washington, District of Columbia
Conditions: Low-grade Glioma, Advanced Solid Tumor
Register for Updates
Doravirine for Persons With Excessive Weight Gain on Integrase Inhibitors and Tenofovir Alafenamide
NCT04636437
Recruiting
The primary purpose of this study is to see if people with HIV who had a significant weight gain after starting INSTI (integrase strand transfer inhibitor)+TAF/FTC (tenofovir alafenamide/emtricitabine) (TAF/3TC (lamivudine)) regimen could either slow their rate of weight gain or lose weight within about 1 year if they switch to a regimen containing doravirine (DOR; a newer, non-nucleoside reverse transcriptase inhibitor medication). The study will also try to see if participants changing from TA... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/21/2023
Locations: Whitman-Walker Institute, Inc. CRS (31791), Washington, District of Columbia
Conditions: HIV Infections
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HostDx Sepsis in the Diagnosis and Prognosis of Emergency Department Patients With Suspected Infections and Suspected Sepsis
NCT04094818
Recruiting
This study will analyze gene expression and other laboratory data from biological samples collected from participants with suspected respiratory, urinary, intra-abdominal, and/or skin & soft tissue infections; or suspected sepsis of any cause.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/21/2023
Locations: Medstar Health Research Institute, Washington, District of Columbia
Conditions: Respiratory Tract Infections, Urinary Tract Infections, Intra-Abdominal Infections, Skin and Soft Tissue Infection, Sepsis, Suspected Meningitis/Encephalitis or Any Other Infection
Register for Updates
Connect to Baby: A Pilot Study of a Parenting and Coparenting Program
NCT06179576
Recruiting
The proposed project is a randomized control trial to assess a novel 6-session parenting and coparenting intervention for low-income parents of infants. Connect to Baby (CTB) will be implemented within one of the largest federally-funded early care and education programs, Early Head Start (EHS), in Washington, DC. To engage both fathers and mothers, CTB recruits parents at the time of birth, capitalizing on the "magic moment" of delivery, and uses father-inclusive digital media content to engage... Read More
Gender:
All
Ages:
Between 2 months and 40 years
Trial Updated:
12/19/2023
Locations: Child Development and Social Policy Lab, Washington, District of Columbia
Conditions: Parenting
Register for Updates
NAPOLI-2: Fluorouracil, Leucovorin, and Nanoliposomal Irinotecan in Biliary Cancer
NCT04005339
Recruiting
This is a study to evaluate the clinical activity of the combination of fluorouracil, leucovorin, and nanoliposomal irinotecan as second-line treatment in patients with advanced biliary tract cancers following gemcitabine and platinum chemotherapy.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/19/2023
Locations: Lombardi Comprehensive Cancer Center, Georgetown University, Washington, District of Columbia
Conditions: Advanced Biliary Tract Cancer
Register for Updates
Brain Oxygen Optimization in Severe TBI, Phase 3
NCT03754114
Recruiting
BOOST3 is a randomized clinical trial to determine the comparative effectiveness of two strategies for monitoring and treating patients with traumatic brain injury (TBI) in the intensive care unit (ICU). The study will determine the safety and efficacy of a strategy guided by treatment goals based on both intracranial pressure (ICP) and brain tissue oxygen (PbtO2) as compared to a strategy guided by treatment goals based on ICP monitoring alone. Both of these alternative strategies are used in s... Read More
Gender:
All
Ages:
14 years and above
Trial Updated:
12/18/2023
Locations: MedStar Washington Hospital Center, Washington, District of Columbia
Conditions: Brain Injuries, Traumatic
Register for Updates