District Of Columbia is currently home to 833 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Washington, Washington, D.C., Washington DC and Washington, Dc. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Protocol CAUSE-03 / CHEETAH
NCT06136091
Recruiting
This is a one-year longitudinal, observational study of 250 urban children and adolescents with asthma and 60 without asthma, ages 6-17 years old. Participants with asthma will require daily controller therapy with inhaled corticosteroids ICS (at least Step 2 therapy). Those without asthma cannot have used asthma medications in the year prior to enrollment and cannot demonstrate bronchodilator reversibility at baseline. Phenotypic characteristics will be established at baseline, and the partici... Read More
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
05/02/2024
Locations: Children's National Medical Center: Children's Research Institute, Washington, District of Columbia
Conditions: Asthma
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Treatment of Hypopigmented Scars With Bimatoprost
NCT06122090
Recruiting
Patients who have hypo-pigmented burn scar will have two scars chosen and randomized to treated scar and control scar. The subject will then have both scars treated with fractional ablative CO2 laser (FLSR). The treated scar will have bimatoprost delivered through the laser channels, while the control will have the vehicle (normal saline) only delivered. The treatment will continue for 14 days with twice daily application. The scars will then be monitored at a 2-week follow-up visit where levels... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/02/2024
Locations: MedStar Washington Hospital Center, Washington, District of Columbia
Conditions: Scars, Hypopigmented Scar, Hypopigmented Skin, Burn Scar, Scarring, Cicatrix, Hypertrophic, Cicatrix, Pigmentation Disorder, Burns Laser
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Immunization With BCG Vaccine to Prevent Tuberculosis Infection
NCT04453293
Recruiting
The purpose of this research is to find out if a single dose of pre-travel vaccination with BCG can lessen tuberculosis (TB) infection by producing an immune response when given to adults traveling to countries with a high burden of TB. BCG will be compared with a placebo (an inactive vaccine). BCG (Japan) is used globally but is not approved for use in the United States, therefore it is considered experimental. Participants choosing to take part in this research study, will be randomly assigned... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/02/2024
Locations: MedStar Washington Hospital Center/MedStar Health Research Institute, Washington, District of Columbia
Conditions: Tuberculosis Infection
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Intravesical LGG VS Saline Bladder Wash RCT
NCT05230511
Recruiting
This is the first ever comparative effectiveness study of an antibiotic-sparing novel self-management intervention to prevent complicated urinary tract infection (UTI).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/01/2024
Locations: MedStar National Rehabilitation Hospital, Washington, District of Columbia
Conditions: Spinal Cord Injuries, Neurogenic Bladder
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Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer
NCT04095364
Recruiting
This phase III trial studies how well letrozole with or without paclitaxel and carboplatin works in treating patients with stage II-IV low-grade serous carcinoma of the ovary, fallopian tube, or peritoneum. Letrozole is an enzyme inhibitor that lowers the amount of estrogen made by the body which in turn may stop the growth of tumor cells that need estrogen to grow. Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/01/2024
Locations: Sibley Memorial Hospital, Washington, District of Columbia
Conditions: Primary Peritoneal Low Grade Serous Adenocarcinoma, Stage II Ovarian Cancer AJCC v8, Stage III Ovarian Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Low Grade Fallopian Tube Serous Adenocarcinoma, Stage II Fallopian Tube Cancer AJCC v8, Stage II Primary Peritoneal Cancer AJCC v8, Stage III Fallopian Tube Cancer AJCC v8, Stage III Primary Peritoneal Cancer AJCC v8, Stage IV Fallopian Tube Cancer AJCC v8, Stage IV Primary Peritoneal Cancer AJCC v8, Ovarian Low Grade Serous Adenocarcinoma
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National Collaborative to Improve Care of Children With Complex Congenital Heart Disease
NCT02852031
Recruiting
The purpose of this initiative is to improve care and outcomes for infants with HLHS by expanding the NPC-QIC national registry to gather clinical care process, outcome, and developmental data on infants with HLHS between diagnosis and 12 months of age, by improving the use of standards into everyday practice across pediatric cardiology centers, and by engaging parents as partners in the process.
Gender:
ALL
Ages:
15 months and below
Trial Updated:
05/01/2024
Locations: Children's National Medical Center, Washington, District of Columbia
Conditions: Hypoplastic Left Heart Syndrome (HLHS)
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Navigating Pregnancy and Parenthood With Lyme Disease
NCT06397794
Recruiting
This is a mixed methods study exploring the experiences of pregnancy and parenting among participants with Lyme disease. Eligible participants will have been diagnosed with Lyme disease (LD), post-treatment Lyme disease syndrome (PTLDS), and/or chronic Lyme (CL) either during or before a prior pregnancy. Participants will complete quantitative surveys on topics such as their medical history, their child(ren)'s development, and demographic information. They will then participate in a qualitative... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: Lyme Disease, Post Treatment Lyme Disease, Chronic Lyme Disease, Tick-Borne Infections, Tick-Borne Diseases, Pregnancy Complications, Parenting
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Connect® Myeloid Disease Registry
NCT01688011
Recruiting
The purpose of the Connect® Myeloid disease registry is to provide unique insights into treatment decisions and treatment patterns as they relate to clinical outcomes of patients with myeloid diseases in routine clinical practice. This disease registry will also evaluate molecular and cellular markers that may provide further prognostic classification which may or may not be predictive of therapy and clinical outcomes.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/30/2024
Locations: MedStar Health Research Institute (Washington), Washington, District of Columbia
Conditions: Myelodysplastic Syndromes, Primary Myelofibrosis, Leukemia, Myeloid, Acute
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Effect of Empagliflozin on Podocyte Specific Proteins in African American Veterans With NDKD
NCT06110130
Recruiting
Primary Objective:To study podocyte specific injury markers in African American Veterans with non-diabetic kidney disease(NDKD), on empagliflozin therapy. Primary Endpoint: Assess the effect of Empagliflozin on podocyte-specific proteins in exosomes isolated from subjects' urine, such as nephrin, podocalyxin and Wilms'Tumor (WT-1) protein. Secondary Objective: 1. Correlate changes in exosome-based podocyte specific proteins with standardized biomarkers of kidney injury including urine albumin... Read More
Gender:
ALL
Ages:
Between 19 years and 90 years
Trial Updated:
04/25/2024
Locations: Washington DC Veterans Affairs Medical Center (688), Washington, District of Columbia
Conditions: Chronic Kidney Diseases
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Social & QoL Behaviors in Parkinson's Disease
NCT06385184
Recruiting
Adults with Parkinson's Disease experience an array of challenges and changes in daily living, behaviors, and functioning throughout the progression of their condition. The investigators want to learn more about the effects of Parkinson's Disease on individuals' social behavior and quality of life (QoL) compared to people of the same age without Parkinson's Disease.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
04/23/2024
Locations: The George Washington University, Washington, District of Columbia
Conditions: Parkinson Disease
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PRP Injections for Genitourinary Syndrome of Menopause
NCT06028009
Recruiting
Platelet-rich plasma (PRP) is autologous blood which has been centrifuged to separate the supernatant resulting in a solution with high concentration of platelets. Injection of PRP stimulates cell growth and can has been proven safe and effective for uses in orthopedics, dermatology, and gynecology. Despite the relative paucity of data, the use of PRP as a therapy for sexual dysfunction and genitourinary symptoms in the setting of menopause has been patented as the O-Shot and V-Shot. This is a s... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: MedStar Lafayette Medical Centre, Washington, District of Columbia
Conditions: PRP, Sexual Function Disturbances, Genitourinary Syndrome of Menopause, Postmenopausal Symptoms, Vaginal Atrophy
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Left Atrial Appendage Occlusion Registry (LAAO Registry)
NCT02699957
Recruiting
The Left Atrial Appendage Occlusion Registry (LAAO Registry™) is designed to assess the prevalence, demographics, management, and outcomes of patients undergoing percutaneous and epicardial based left atrial appendage occlusion procedures to reduce the risk of stroke. Patient-level data will be submitted by participating hospitals on a quarterly basis to the American College of Cardiology Foundation's National Cardiovascular Data Registry (NCDR). The primary aims of the LAAO Registry are to opti... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/17/2024
Locations: American College of Cardiology/National Cardiovascular Data Registry (NCDR), Washington, District of Columbia
Conditions: Atrial Fibrillation
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