District Of Columbia is currently home to 853 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Washington, Washington, D.C., Washington DC and Washington, Dc. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Inspiring New Science In Guiding Healthcare in Turner Syndrome Registry
NCT05052606
Recruiting
INSIGHTS is a registry research study that collects key information on medical history for girls and women with Turner syndrome and the clinical care they receive. This includes genetic tests, imaging, medications, and more for hundreds of patients seen at a number of clinics across the US. In addition to learning a lot about the current state of health for individuals with TS, INSIGHTS serves as an infrastructure to conduct future studies are meaningful to patients and their families.
Gender:
FEMALE
Ages:
All
Trial Updated:
09/27/2024
Locations: Children's National, Washington, District of Columbia
Conditions: Turner Syndrome
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Immunotherapy for Malignant Pediatric Brain Tumors Employing Adoptive Cellular Therapy (IMPACT)
NCT06193759
Recruiting
This is an open-label phase 1 safety and feasibility study that will employ multi-tumor antigen specific cytotoxic T lymphocytes (TSA-T) directed against proteogenomically determined personalized tumor-specific antigens (TSA) derived from a patient's primary brain tumor tissues. Young patients with embryonal central nervous system (CNS) malignancies typically are unable to receive irradiation due to significant adverse effects and are treated with intensive chemotherapy followed by autologous st... Read More
Gender:
ALL
Ages:
Between 1 day and 4 years
Trial Updated:
09/25/2024
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: Medulloblastoma, Childhood, Atypical Teratoid/Rhabdoid Tumor of CNS, Embryonal Tumor With Multilayered Rosettes, Pineoblastoma, Embryonal Tumor of CNS
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Improving Genetic Counseling for BRCA+ Mothers
NCT04258280
Recruiting
Genetic counseling and testing for hereditary breast cancer may reveal that you, and possibly your blood relatives, are at increased risk for the disease across the lifespan. This includes biological children, both male and female. We do not yet know the best ways to educate mothers who have a risk gene (are BRCA+) about whether, when, and how to share genetic information with their children or manage their thoughts and feelings. The purpose of this study is to help mothers make more informed ch... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
09/25/2024
Locations: MedStar Georgetown University Hospital, Washington, District of Columbia
Conditions: Breast Cancer
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Novel Device for Ultrasound-guided Pediatric Vessel Cannulations
NCT04039490
Recruiting
Clinical Trial to investigate whether the use of a novel device to be used in conjunction with ultrasound in pediatric vessel cannulations is superior to ultrasound-only pediatric vessel cannulations in terms of number of cannulation attempts.
Gender:
ALL
Ages:
Between 1 month and 17 years
Trial Updated:
09/25/2024
Locations: Children's National Medical Center, Washington, District of Columbia
Conditions: Clinical Procedures Which Require Vessel Cannulations in Pediatric Patients
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Assessment of the Safety, Tolerability, and Effectiveness of Rifapentine Given Daily for LTBI
NCT03474029
Recruiting
This study is conducted to compare the safety and effectiveness of a novel short 6-week regimen of daily rifapentine (6wP, experimental arm) with a comparator arm of 12-16 weeks of rifamycin-based treatment (standard of care, control arm) of latent M. tuberculosis infection (LTBI). This trial is conducted among persons who are at increased risk of progression to tuberculosis (TB) and require treatment of LTBI. The study will be conducted in low, medium and high TB incidence settings that have t... Read More
Gender:
ALL
Ages:
12 years and above
Trial Updated:
09/25/2024
Locations: George Washington University, Washington, District of Columbia
Conditions: Latent Tuberculosis
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A Phase 3B Study to Evaluate Bone Mineral Density with Long-Term Use of Relugolix Combination Tablet in Women with Uterine Fibroids or Endometriosis
NCT05862272
Recruiting
The purpose of this clinical trial to characterize changes in bone mineral density during continuous treatment with relugolix combination tablet for up to 48 months (4 years) and 1 year of post-treatment follow-up in premenopausal women with heavy menstrual bleeding associated with uterine leiomyomas (fibroids) or with moderate-to-severe pain associated with endometriosis.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
09/24/2024
Locations: Washington, Washington, District of Columbia
Conditions: Uterine Fibroids, Endometriosis
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STOP-HER2: Stopping Trastuzumab in HER2+ MBC
NCT05721248
Recruiting
This study is being done to see if anti-HER2 treatment be safely stopped in patients with HER2-positive metastatic breast cancer (MBC) that have had exceptional response to treatment. Exceptional response" is considered as cancer progression being controlled for three years or more since starting anti-HER2 treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/24/2024
Locations: Georgetown University Medical Center, Washington, District of Columbia
Conditions: Breast Cancer, Metastatic Breast Cancer, HER2-positive Breast Cancer
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Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
NCT03827694
Recruiting
This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (PIFI).
Gender:
ALL
Ages:
Between 120 days and 21 years
Trial Updated:
09/24/2024
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: Pulmonary Invasive Aspergillosis, Pulmonary Invasive Fungal Infections
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Consent for Use of Stored Patient Specimens for Future Testing
NCT00031408
Recruiting
The purpose of this study is to obtain informed consent to use stored human biological materials (HBM) (e.g., blood and other tissues) for future studies that may include genetic testing.
Gender:
ALL
Ages:
All
Trial Updated:
09/20/2024
Locations: Georgetown Univ Med Ctr, Washington, District of Columbia
Conditions: HIV Infections
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Radiation, Immunotherapy and PARP Inhibitor in Triple Negative Breast Cancer
NCT04837209
Recruiting
This research study is looking to see whether the combination of Dostarlimab and Niraparib plus Radiation Therapy (RT) is safe and effective in participants with metastatic triple negative breast cancer. The names of the study treatment involved in this study are: * Dostarlimab * Niraparib * Radiation Therapy (RT), which is given per standard of care.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/19/2024
Locations: Sibley Memorial Hospital, Washington, District of Columbia
Conditions: Breast Cancer, Triple Negative Breast Cancer
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First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors
NCT06554795
Recruiting
A Phase 1/2a First-in-Human Study of DB-1419 in Advanced/Metastatic Solid Tumors
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/17/2024
Locations: Site USA06-0, Washington, D.C., District of Columbia
Conditions: Solid Tumor, Adult
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Cooperative Assessment of Late Effects for SCD Curative Therapies
NCT05153967
Recruiting
Sickle Cell Disease is one of the most common genetic diseases in the United States, occurring in approximately 1 in 400 births. Approximately 100,000 individuals are diagnosed with SCD in the United States. Mortality for children with SCD has decreased substantially over the past 4 decades, with \>99% of those born in high resource settings, including the United States, France, and England, now surviving to 18 years of age. However, the life expectancy of adults with SCD is severely shortened.... Read More
Gender:
ALL
Ages:
Between 4 years and 65 years
Trial Updated:
09/16/2024
Locations: Children's National Medical Center, Washington, District of Columbia
Conditions: Sickle Cell Disease, Pulmonary Disease, Renal Disease, Heart Disease
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