District Of Columbia is currently home to 920 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Washington, Washington, D.C., Washington DC and Washington, Dc. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Portico Re-sheathable Transcatheter Aortic Valve System US IDE Trial
NCT02000115
Recruiting
The objective of the PORTICO pivotal IDE trial is to evaluate the safety and effectiveness of the St Jude Medical (SJM) Portico Transcatheter Heart Valve and Delivery Systems (Portico) in the treatment of severe symptomatic aortic stenosis via transfemoral and alternative delivery methods in high risk and extreme risk patients.
Gender:
All
Ages:
21 years and above
Trial Updated:
10/24/2023
Locations: Washington Hospital Center, Washington, District of Columbia
Conditions: Aortic Valve Stenosis
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Mood Alterations in the Patients With Non-Muscle Invasive Bladder Cancer Treated With BCG
NCT05672615
Recruiting
The purpose of this study is to evaluate mood changes in patients with Non-Muscle Invasive Bladder Cancer who are receiving intravesical Bacillus Calmete-Guerin (BCG). Patients with Non-Muscle Invasive Bladder Cancer receiving intravesical treatments are eligible to participate in this study. Participation involves providing research blood and urine samples prior to the start of treatment and throughout the treatment course. The study team will also collect participant's medical history and clin... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/23/2023
Locations: Sibley Memorial Hospital, Washington, District of Columbia
Conditions: Non-Muscle Invasive Bladder Cancer
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Gender Related Coping and Survivorship for Genitourinary Cancers
NCT05649306
Recruiting
This research is being done to learn more about coping and survivorship of women with bladder cancer, specifically regarding psychosocial distress and sexual dysfunction. This study is a non-therapeutic study and will randomize participants to a standard of care group and education group. Patients in both groups will be asked to complete surveys regarding their mood and sexual function. Patients in the intervention group will be asked to complete attendance diaries regarding educational and supp... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
10/23/2023
Locations: Sibley Memorial Hospital, Washington, District of Columbia
Conditions: Bladder Cancer
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The Selfie Study- Assessing Novel Markers for Cervical Cancer Screening From Self-collected Samples
NCT04423679
Recruiting
Cervical cancer is primarily caused by Human Papillomaviruses (HPV). Testing for HPV in cervical samples is now an option for cervical cancer screening. HPV can also be tested from self-collected samples which may help to improve access to screening, since it does not require a doctor visit. However, many women will test positive for HPV who are not at high risk for cervical cancer. Therefore, additional ("triage") tests are needed to determine which women testing HPV-positive require additional... Read More
Gender:
Female
Ages:
Between 30 years and 69 years
Trial Updated:
10/23/2023
Locations: Medical Faculty Associates, Washington, District of Columbia
Conditions: Human Papilloma Virus, Cervical Cancer, CIN 2/3
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Spinal COrd NeuromodulaTor by SpIneX and ScoNE to Treat NeurogeniC BladdEr - SCONE "CONTINENCE" Clinical Study
NCT05301335
Recruiting
The purpose of this study is to evaluate the effectiveness and safety of SCONE neuromodulation therapy after 12 weeks of therapy in comparison to inactive sham control in improving symptoms of Neurogenic Lower Urinary Tract Dysfunction
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
10/19/2023
Locations: Medstar National Rehab, Washington, District of Columbia
Conditions: Neurogenic Bladder, Stroke, Multiple Sclerosis, Spinal Cord Injuries (Complete and Incomplete)
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Evaluation of the Safety and Efficacy of ELA026 in Participants With Secondary Hemophagocytic Lymphohistiocytosis
NCT05416307
Recruiting
Hemophagocytic lymphohistiocytosis is a rare, aggressive and life-threatening syndrome of excessive immune activation. ELA026 is a fully human IgG1 SIRP-directed monoclonal antibody designed to reduce the myeloid and T cells driving the inflammation. The purpose of this study is to assess the safety, efficacy pharmacokinetics and pharmacodynamics of ELA026 in participants with secondary hemophagocytic lymphohistiocytosis.
Gender:
All
Ages:
6 years and above
Trial Updated:
10/18/2023
Locations: MedStar Georgetown, Washington, District of Columbia
Conditions: Secondary Hemophagocytic Lymphohistiocytosis (sHLH)
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Social Risk Factors and Discrimination in Cancer Survivorship
NCT05301114
Recruiting
The objective of the proposed study is to scale social risk factor screening and referral for cancer survivors and to solidify information exchange between clinical and community settings in order to improve survivor health and well-being. This will be completed through three primary aims: 1) To ascertain workflow and map community resources needed to facilitate social risk factor screening and referral for breast and prostate cancer survivors in Washington, District of Columbia. 2) To determine... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: MedStar Washington Hospital Center, Washington, District of Columbia
Conditions: Social Determinants of Health, Breast Cancer, Prostate Cancer, Health Equity, Disparities
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Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma
NCT03860883
Recruiting
Patients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin. There is evidence that less radical margins of excision may be just as safe. This is a randomised controlled trial of 1 cm versus 2 cm margin of excision of the primary lesion for adult patients with stage II primary invasive cutaneous melanomas (AJCC 8th edition) to determine differences in disease-free survival. A reduction in margins is expected to improve patient quality of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/17/2023
Locations: MedStar Georgetown University Hospital, Washington, District of Columbia
Conditions: Cutaneous Melanoma, Stage II
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Safety and Efficacy of Quizartinib in Children and Young Adults With Acute Myeloid Leukemia (AML), a Cancer of the Blood
NCT03793478
Recruiting
Quizartinib is an experimental drug. It is not approved for regular use. It can only be used in medical research. Children or young adults with a certain kind of blood cancer (FLT3-ITD AML) might be able to join this study if it has come back after remission or is not responding to treatment.
Gender:
All
Ages:
Between 1 month and 21 years
Trial Updated:
10/11/2023
Locations: Children's National Medical Center, Washington, District of Columbia
Conditions: Acute Myeloid Leukemia
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Pembrolizumab and Lenvatinib in Advanced Cervical Cancer
NCT04865887
Recruiting
This is a phase II trial of combination therapy of pembrolizumab and lenvatinib in patients with locally advanced or metastatic cervical cancer that had failed first line of therapy. The hypothesis is the combination of lenvatinib and pembrolizumab will overcome vascular endothelial growth factor (VEGF)-mediated immunosuppression to enhance the response of patients with locally advanced or metastatic cervical cancer.
Gender:
Female
Ages:
18 years and above
Trial Updated:
10/10/2023
Locations: MedStar Georgetown University Hospital, Washington, District of Columbia
Conditions: Cervical Cancer, Metastatic Cervical Cancer
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Device Feasibility and Acceptability to Improve Insomnia in Cancer
NCT05875129
Recruiting
Sleep disruption is common among young adult cancer survivors for a variety of reasons. Cognitive behavioral therapy for insomnia (CBT-I) has been shown to improve chronic sleep disorders. This project will test the feasibility and acceptability of a new voice-activated virtual assistant (VAVA) device to deliver CBT-I to improve sleep among young adult cancer survivors with chronic sleep disorders.
Gender:
All
Ages:
Between 18 years and 39 years
Trial Updated:
10/04/2023
Locations: MedStar Washington Hospital Center, Washington, District of Columbia
Conditions: Cancer, Insomnia Chronic
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A Single-arm, Multicenter Study to Assess the Efficacy, Safety, and Tolerability of P1101 in Adults With ET
NCT05482971
Recruiting
A Single-arm, Multicenter Study to Assess the Efficacy, Safety, and Tolerability of Ropeginterferon alfa-2b-njft (P1101) in Adult Patients with Essential Thrombocythemia
Gender:
All
Ages:
18 years and above
Trial Updated:
10/01/2023
Locations: Georgetown University Medical Center, Washington, District of Columbia
Conditions: Essential Thrombocythemia
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