District Of Columbia is currently home to 836 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Washington, Washington, D.C., Washington DC and Washington, Dc. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Group Visits for High Risk Type 1 Diabetes (T1D)
NCT05431686
Recruiting
The investigators propose to conduct a pilot prospective cohort study to assess the impact of shared medical appointments (SMA) visits in underserved youth with poorly controlled type 1 diabetes (T1D). The trial will employ an enrollment visit, SMA visits every 3 months over a 12 month study period, followed by a 6-month observational period to assess feasibility and acceptability of SMA and the impact on glycemic control, self-management skills, and health related quality of life.
Gender:
ALL
Ages:
8 years and above
Trial Updated:
08/31/2023
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: Type 1 Diabetes
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Nerivio Device for Treatment of New Daily Headache Persistence (NDHP)
NCT05310227
Recruiting
The goal of this study is to examine the effects of the Remote Electrical Neuromodulation (REN) device on adolescents ages 12-17 who have been diagnosed with New Daily Persistent Headache (NDPH). Pediatric patients with a diagnosis of new daily persistent headache are typically resistant to standard pharmacologic treatments and often experience systemic side effects related to medications; thus, REN offers the potential for an exciting new treatment option for patients with refractory headache d... Read More
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
08/31/2023
Locations: Children's National Medical Center, Washington, District of Columbia
Conditions: New Daily Persistent Headache (NDPH)
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AltaValve Early Feasibility Study Protocol
NCT03997305
Recruiting
Prospective, single-arm, multicenter study to evaluate the safety and performance of the AltaValve for the treatment of moderate to severe or severe mitral valve regurgitation in subjects who are considered high risk for mortality and morbidity from conventional open-heart surgery.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/31/2023
Locations: MedStar Washington Hospital, Washington, District of Columbia
Conditions: Mitral Regurgitation, Mitral Insufficiency, Mitral Valve Incompetence, Mitral Valve Regurgitation, Mitral Incompetence
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Transform CV Risk in Diabetes
NCT05948969
Recruiting
This initiative supports a real-world study of practice and physician prescribing patterns and a quality improvement initiative evaluating best practices (including clinical decision support, facilitated referral to cardiometabolic team-based care model, and general educational tools/resources) to im-prove use of guideline-directed therapeutics known to lower cardiovascular risk (CV) in patients with type 2 diabetes (T2D).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/13/2023
Locations: Multiple sites nationwide, Washington, District of Columbia
Conditions: Type 2 Diabetes
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Diabetic Foot Ulcers-Comparing Transforming Powder to Standard of Care
NCT05046158
Recruiting
Phase IV, randomized, prospective, multi-center, open-label, comparison of transforming powder dressing to standard of care dressing for healing diabetic foot ulcers.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
06/27/2023
Locations: MedStar Georgetown University Hospital, Washington, District of Columbia
Conditions: Diabetic Foot Ulcer
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Transcatheter Aortic Prosthesis Function: A Long-term Follow-up Study
NCT03002272
Recruiting
In this observational study, the investigators will enroll subjects who underwent TAVR or SAVR more than 3 years ago. Clinical and procedural data from the implant/surgery will be collected, alongside clinical and echocardiographic data from subsequent follow-up visits.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/25/2023
Locations: Washington Hospital Center, Washington, District of Columbia
Conditions: Aortic Valve Replacement
Register for Updates
Impact of Nilotinib on Safety, Tolerability, Pharmacokinetics and Biomarkers in Dementia With Lewy Bodies
NCT04002674
Recruiting
Dementia with Lewy Bodies (DLB) is an alphasynucleinopathy and the second most common form of dementia in the elderly. DLB shares striking neuropathological and clinical similarities with both Parkinson's disease (PD) and Alzheimer's disease (AD). Nilotinib (Tasigna®, AMN107, Novartis, Switzerland) is approved by the FDA and is well tolerated for CML treatment at oral doses of 600-800mg daily. The Investigators propose to perform a phase II randomized, double blinded, placebo controlled study to... Read More
Gender:
ALL
Ages:
Between 25 years and 90 years
Trial Updated:
05/11/2023
Locations: MedStar Georgetown University Hospital, Washington, District of Columbia
Conditions: Dementia With Lewy Bodies
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Omalizumab Before Onset of Exacerbations
NCT05332067
Recruiting
OBOE is a prospective, pilot, parallel group RCT with the overall aim of examining the effect of a single dose of anti-IgE (omalizumab) vs. placebo administered at the onset of URIs in the fall season among highly exacerbation-prone, urban, and atopic youth aged 6-17 years with persistent asthma. OBOE will recruit and randomize participants over 3 years (3 annual cohorts of participants). Recruitment for each of the yearly cohorts of OBOE will begin in February. Each cohort will be followed for... Read More
Gender:
ALL
Ages:
Between 6 years and 17 years
Trial Updated:
03/13/2023
Locations: Children's National Hospital, Washington, District of Columbia
Conditions: Asthma in Children, Atopy, Viral Upper Respiratory Infection
Register for Updates
Trigger Point Injections in Anterior Cervical Surgery
NCT04640896
Recruiting
To achieve appropriate exposure for an anterior neck surgery (for example an Anterior Cervical Discectomy and Fusion or ACDF), patients are positioned supine with their neck extended. Due to being in this position, patients frequently complain of posterior neck stiffness and pain postoperatively in addition to the anterior incisional pain. This posterior cervical pain can be classified as myofascial pain. Cervical myofascial pain is thought to be the result of overuse or trauma to the supportin... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/07/2022
Locations: George Washington University Hospital, Washington, District of Columbia
Conditions: Myofacial Pain, Pain, Neck, Pain, Back, Cervical Fusion
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2-level Cervical Disc Replacement Comparing Prodisc C SK & Vivo to Mobi-C
NCT04012996
Recruiting
A multi-center, prospective, randomized, controlled comparison of the prodisc C SK and prodisc C Vivo to the control, a similar, legally marketed total disc replacement device in subjects with symptomatic cervical disc disease (SCDD).
Gender:
ALL
Ages:
Between 18 years and 69 years
Trial Updated:
10/27/2022
Locations: Georgetown University Hospital, Washington, District of Columbia
Conditions: Symptomatic Cervical Disc Disease
Register for Updates
Physiologic Signals and Signatures With the Accuryn Monitoring System - The Accuryn Registry
NCT04669548
Recruiting
The Accuryn Registry Study is an open-ended, global, multi-center, retrospective and prospective, single-arm data collection study with an FDA cleared device. The target population are cardiovascular surgery patients. Physiologic data measurements will be collected from enrolled subjects using electronic medical records and data streams via the Accuryn Monitoring System.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2022
Locations: George Washington University Hospital, Washington, District of Columbia
Conditions: Intraabdominal Hypertension, Abdominal Compartment Syndrome, Acute Kidney Injury, Cardiovascular Surgery
Register for Updates
STS/ACC Transcatheter Valve Therapy Registry (TVT Registry)
NCT01737528
Recruiting
The TVT Registry™ is a benchmarking tool developed to track patient safety and real-world outcomes related to the transcatheter aortic valve replacement (TAVR) procedure. Created by The Society of Thoracic Surgeons (STS) and the American College of Cardiology (ACC), the TVT Registry is designed to monitor the safety and efficacy of this new procedure for the treatment of aortic stenosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/23/2022
Locations: American College of Cardiology, Washington, District of Columbia
Conditions: Aortic Valve Stenosis
Register for Updates