There are currently 535 clinical trials in Gainesville, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Florida /ID# 144834, University of Florida Health Science Center - Gainesville, University of Florida Shands Cancer Center and Sarkis Clinical Trials. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Regeneration of Acutely Injured Nerves with Temporary Electrical Stimulation
NCT05721261
Recruiting
A novel temporary peripheral nerve stimulation system that delivers a single dose of electrical stimulation therapy for 1 hour will be evaluated for safety and effectiveness.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/06/2025
Locations: University of Florida Health, Gainesville, Florida
Conditions: Nerve Injury
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Improving Blood Pressure Control Among Food Insecure Hypertensive Adults
NCT05877898
Recruiting
The overall objective of this project is to assess the feasibility, acceptability, and appropriateness of adapted community health worker (CHW)-led implementation strategies designed to improve intake of fruits and vegetables and reduce BP among patients with hypertension experience food insecurity.
Gender:
ALL
Ages:
Between 18 years and 69 years
Trial Updated:
02/06/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Hypertension
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Effects of a Very Low Carbohydrate Ketogenic Diet or Mediterranean Diet on Markers of Musculoskeletal Health in Older Adults
NCT06203392
Recruiting
Preclinical data indicate that very low carbohydrate ketogenic diets (KD) may prevent progression of age-related sarcopenia (skeletal muscle decline) but also may disturb bone metabolism. The investigators will pilot test a randomized trial comparing the effects of short-term adaptation to a well-formulated ketogenic diet and Mediterranean diet on markers of bone metabolism and muscle function in older adults. The expected results will help inform the benefit-risk assessment for older patients c... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
02/06/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Aging, Musculoskeletal Diseases
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A Trial Comparing Unrelated Donor BMT with IST for Pediatric and Young Adult Patients with Severe Aplastic Anemia (TransIT, BMT CTN 2202)
NCT05600426
Recruiting
Severe Aplastic Anemia (SAA) is a rare condition in which the body stops producing enough new blood cells. SAA can be cured with immune suppressive therapy or a bone marrow transplant. Regular treatment for patients with aplastic anemia who have a matched sibling (brother or sister), or family donor is a bone marrow transplant. Patients without a matched family donor normally are treated with immune suppressive therapy (IST). Match unrelated donor (URD) bone marrow transplant (BMT) is used as a... Read More
Gender:
ALL
Ages:
Between 0 years and 25 years
Trial Updated:
02/05/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Severe Aplastic Anemia
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Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans
NCT04064086
Recruiting
This study is intended to correct an important systemic deficit in the care of chronic kidney disease (CKD), VHA's fourth most common healthcare condition with high mortality and healthcare burden. Currently, many Veterans with CKD have poor awareness of their condition. This leads to suboptimal care. The investigators anticipate that the proposed comprehensive pre-end stage renal disease (ESRD) education (CPE) will enhance Veterans' CKD knowledge and their confidence in making an informed selec... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2025
Locations: North Florida/South Georgia Veterans Health System, Gainesville, FL, Gainesville, Florida
Conditions: Chronic Kidney Disease, End Stage Renal Disease, Hemodialysis, Peritoneal Dialysis
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The Fuel and Rhythm (FAR) Phase 2 Study
NCT05482711
Recruiting
Both fuel metabolism and circadian rhythms have emerged as important targets to improve cellular and mitochondrial health and ultimately affect function in older adults. Thus, the purpose of this study is to develop minimally invasive measures that will allow us to accurately assess and detect changes in fuel metabolism and circadian rhythms in older adults following time-restricted eating.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
02/05/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Aging
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Krill Oil for Pain in Elders
NCT06580912
Recruiting
Chronic musculoskeletal pain contributes to mobility disability among older adults. Nutritional interventions, like omega-3 fatty acids, may help manage pain and improve physical function. Supplementation with krill oil may offer advantages to fish oil due to better absorption and additional nutrients. This pilot study aims to assess the feasibility of a clinical trial to determine the impact of krill oil supplementation on pain and function in older adults, informing future research.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
02/04/2025
Locations: UF Claude D. Pepper Older Americans Independence Center, Gainesville, Florida
Conditions: Chronic Musculoskeletal Pain
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Tourette Deep Brain Stimulation (DBS) Target Detection & Suppression
NCT05371041
Recruiting
The investigators will implant and monitor 8 research subjects with a subcortical closed-loop system for detection and suppression of tics. The project will use the FDA-approved "Medtronic Percept PC" device, which is an implantable neurostimulator capable of recording neural signals. The study will target the CM nucleus of the thalamus and the aGPi in each brain hemisphere from each subject and we will connect the two leads placed in each brain hemisphere to two Percept devices.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
02/04/2025
Locations: Norman Fixel Institute for Neurological Diseases - University of Florida, Gainesville, Florida
Conditions: Tourette Syndrome
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A Study Assessing KB407 for the Treatment of Cystic Fibrosis
NCT05504837
Recruiting
This study will evaluate safety and tolerability of ascending doses of nebulized KB407 in adults with cystic fibrosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/31/2025
Locations: University of Florida, Gainesville, Gainesville, Florida
Conditions: Cystic Fibrosis
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Use of CBD in the Treatment of Anxiety
NCT06672666
Recruiting
This study will examine the doses, safety, and test the preliminary efficacy of hemp-derived CBD product for improving anxiety symptoms and sleep disturbances among individuals with anxiety. A 4-week, randomized, double-blind, placebo-controlled trial will be conducted to determine the safety, tolerability, preliminary efficacy, and acceptability of 50 to 150 mg/day of CBD. The treatment period will consist of a two-week titration period followed by a 2- week maintenance period. In addition, the... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
01/31/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Anxiety, Generalized Anxiety Disorder, Sleep Problems
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The Potential of Kava in Enabling Tobacco Cessation - Its Holistic Effects in Managing Stress and Insomnia Associated With Abstinence
NCT05814055
Recruiting
This study will evaluate the compliance with a daily kava regimen among active smokers who have an intention to quit smoking. This study will also investigate whether kava use can facilitate tobacco cessation, reduce stress, and improve sleep.
Gender:
ALL
Ages:
Between 21 years and 99 years
Trial Updated:
01/31/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Smoking
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Safety, PK and Efficacy of ONC-392 in Monotherapy and in Combination of Anti-PD-1 in Advanced Solid Tumors and NSCLC
NCT04140526
Recruiting
This is a First-in-Human Phase IA/IB/II open label dose escalation study of intravenous (IV) administration of ONC-392, a humanized anti-CTLA4 IgG1 monoclonal antibody, as single agent and in combination with pembrolizumab in participants with advanced or metastatic solid tumors and non-small cell lung cancers.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/30/2025
Locations: University of Florida Health Cancer Center, Gainesville, Florida
Conditions: Non Small Cell Lung Cancer, Advanced Solid Tumor, Metastatic Melanoma, Metastatic Head and Neck Carcinoma, Metastatic Renal Cell Carcinoma, Metastatic Colorectal Cancer, Sarcomas, Metastatic Prostate Cancer, Ovarian Cancer, Small Cell Lung Cancer, Metastatic Breast Cancer, Pancreas Cancer, Gastric Cancer, Esophageal Cancer, Gastroesophageal Junction Adenocarcinoma, Cervical Cancer, Adenoid Cystic Carcinoma, Salivary Gland Cancer, Urothelial Carcinoma
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