There are currently 536 clinical trials in Gainesville, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Florida /ID# 144834, University of Florida Health Science Center - Gainesville, University of Florida Shands Cancer Center and University of Florida College of Medicine. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder
NCT06480383
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled study evaluating the efficacy, safety, and tolerability of ITI-1284 compared with placebo as adjunctive therapy to GAD treatment in patients meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria for GAD who have an inadequate response to ongoing GAD treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: Clinical Site, Gainesville, Florida
Conditions: Generalized Anxiety Disorder
Register for Updates
Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder
NCT06701903
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy, safety, and tolerability of ITI-1284 as monotherapy treatment in patients meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria for GAD in patients who have had inadequate response to generalized anxiety disorder treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: Clinical Site, Gainesville, Florida
Conditions: Generalized Anxiety Disorder
Register for Updates
REBYOTA™ Prospective Registry
NCT05835219
Recruiting
This is a prospective observational cohort study designed to collect data on patients who received REBYOTA™ for the prevention of rCDI in the routine care setting. As all data collected for this study are observational, the decision to prescribe REBYOTA™ is at the treating physician's discretion and independent from the decision to enroll the patient in the study. Data will be collected from patients' medical records after obtaining informed consent. Data about clinical history, CDI events (prim... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2025
Locations: Ferring Investigational Site, Gainesville, Florida
Conditions: Recurrence of Clostridium Difficile Infection
Register for Updates
Healthy Aging Through Movement
NCT05772884
Recruiting
This study aims to examine the effectiveness of a supervised aerobic exercise program for persons with Opioid Use Disorder (OUD). Participants will be enrolled in a 12-week supervised aerobic exercise intervention.
Gender:
ALL
Ages:
Between 21 years and 64 years
Trial Updated:
02/10/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Opioid Use Disorder
Register for Updates
Diabetes RElated to Acute Pancreatitis and Its Mechanisms: Metabolic Outcomes Using Novel CGM Metrics
NCT06401577
Recruiting
The DREAM-ON study will investigate whether continuous glucose monitoring (CGM) is useful to predict risk for developing diabetes mellitus (DM) and pre-diabetes mellitus (PDM), the need for insulin therapy among those who develop DM, and to determine whether CGM can provide insight into the pathophysiology and DM subtype among participants who have experienced an episode of acute pancreatitis (AP). Thus, the results of the DREAM-ON study could inform future clinical practice guidelines for the m... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
02/07/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Acute Pancreatitis
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Effects of a Very Low Carbohydrate Ketogenic Diet or Mediterranean Diet on Markers of Musculoskeletal Health in Older Adults
NCT06203392
Recruiting
Preclinical data indicate that very low carbohydrate ketogenic diets (KD) may prevent progression of age-related sarcopenia (skeletal muscle decline) but also may disturb bone metabolism. The investigators will pilot test a randomized trial comparing the effects of short-term adaptation to a well-formulated ketogenic diet and Mediterranean diet on markers of bone metabolism and muscle function in older adults. The expected results will help inform the benefit-risk assessment for older patients c... Read More
Gender:
ALL
Ages:
60 years and above
Trial Updated:
02/06/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Aging, Musculoskeletal Diseases
Register for Updates
Trial to Evaluate and Assess the Effect of Comprehensive Pre-ESKD Education on Home Dialysis Use in Veterans
NCT04064086
Recruiting
This study is intended to correct an important systemic deficit in the care of chronic kidney disease (CKD), VHA's fourth most common healthcare condition with high mortality and healthcare burden. Currently, many Veterans with CKD have poor awareness of their condition. This leads to suboptimal care. The investigators anticipate that the proposed comprehensive pre-end stage renal disease (ESRD) education (CPE) will enhance Veterans' CKD knowledge and their confidence in making an informed selec... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/05/2025
Locations: North Florida/South Georgia Veterans Health System, Gainesville, FL, Gainesville, Florida
Conditions: Chronic Kidney Disease, End Stage Renal Disease, Hemodialysis, Peritoneal Dialysis
Register for Updates
The Fuel and Rhythm (FAR) Phase 2 Study
NCT05482711
Recruiting
Both fuel metabolism and circadian rhythms have emerged as important targets to improve cellular and mitochondrial health and ultimately affect function in older adults. Thus, the purpose of this study is to develop minimally invasive measures that will allow us to accurately assess and detect changes in fuel metabolism and circadian rhythms in older adults following time-restricted eating.
Gender:
ALL
Ages:
65 years and above
Trial Updated:
02/05/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Aging
Register for Updates
Krill Oil for Pain in Elders
NCT06580912
Recruiting
Chronic musculoskeletal pain contributes to mobility disability among older adults. Nutritional interventions, like omega-3 fatty acids, may help manage pain and improve physical function. Supplementation with krill oil may offer advantages to fish oil due to better absorption and additional nutrients. This pilot study aims to assess the feasibility of a clinical trial to determine the impact of krill oil supplementation on pain and function in older adults, informing future research.
Gender:
ALL
Ages:
60 years and above
Trial Updated:
02/04/2025
Locations: UF Claude D. Pepper Older Americans Independence Center, Gainesville, Florida
Conditions: Chronic Musculoskeletal Pain
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The Potential of Kava in Enabling Tobacco Cessation - Its Holistic Effects in Managing Stress and Insomnia Associated With Abstinence
NCT05814055
Recruiting
This study will evaluate the compliance with a daily kava regimen among active smokers who have an intention to quit smoking. This study will also investigate whether kava use can facilitate tobacco cessation, reduce stress, and improve sleep.
Gender:
ALL
Ages:
Between 21 years and 99 years
Trial Updated:
01/31/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Smoking
Register for Updates
Use of CBD in the Treatment of Anxiety
NCT06672666
Recruiting
This study will examine the doses, safety, and test the preliminary efficacy of hemp-derived CBD product for improving anxiety symptoms and sleep disturbances among individuals with anxiety. A 4-week, randomized, double-blind, placebo-controlled trial will be conducted to determine the safety, tolerability, preliminary efficacy, and acceptability of 50 to 150 mg/day of CBD. The treatment period will consist of a two-week titration period followed by a 2- week maintenance period. In addition, the... Read More
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
01/31/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Anxiety, Generalized Anxiety Disorder, Sleep Problems
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Senolytics To slOw Progression of Sepsis (STOP-Sepsis) Trial
NCT05758246
Recruiting
The long-term goal is to test the clinical efficacy of senolytic therapies to reduce progression to and severity of sepsis in older patients. The central hypothesis is that a threshold burden of SnCs predisposes to a SASP mediated dysfunctional response to PAMPs, contributing to a disproportionate burden of sepsis in older patients. The study hypothesizes timely treatment with fisetin will interrupt this pathway. A multicenter, randomized, adaptive allocation clinical trial to identify the most... Read More
Gender:
ALL
Ages:
65 years and above
Trial Updated:
01/30/2025
Locations: University of Florida, Gainesville, Florida
Conditions: Sepsis, Acute Infection, Organ Failure
Register for Updates