There are currently 1290 clinical trials in Miami, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Miami, GSK Investigational Site, University of Miami Miller School of Medicine-Sylvester Cancer Center and University of Miami Miller School of Medicine. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Preservation of Swallowing in Respected Oral Cavity Squamous Cell Carcinoma: Examining Radiation Volume Effects (PRESERVE): A Randomized Trial
NCT03997643
Recruiting
The goal of this randomized treatment study is to formally compare quality of life in patients with at least one pN0 hemi-neck after resection of a squamous cell carcinoma of the oral cavity treated with a primary radiation therapy versus a secondary targeted radiation therapy approach, to provide a high level of evidence to guide the selection of treatment options.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/02/2023
Locations: Miami Cancer Institute, Miami, Florida
Conditions: Head and Neck Cancer
Register for Updates
Safety and Efficacy of APG-157 in Head and Neck Cancer
NCT05312710
Recruiting
The purpose of this clinical research study is to study safety and efficacy of orally administered APG-157 as the neoadjuvant/induction therapy in newly diagnosed, locally advanced patients with Head & Neck Cancer of oral cavity and/or oropharynx. The study hypothesis is that neoadjuvant use of APG-157 will reduce the tumor burden prior to any definitive therapy to improve the outcomes over current standard of care.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/01/2023
Locations: University of Miami Sylvester Comprehensive Cancer Center, Miami, Florida
Conditions: Head and Neck Cancer, Squamous Cell Carcinoma of Oral Cavity, Squamous Cell Carcinoma of the Oropharynx
Register for Updates
Study of RP1 Monotherapy and RP1 in Combination With Nivolumab
NCT03767348
Recruiting
RPL-001-16 is a Phase 1/2, open label, dose escalation and expansion clinical study of RP1 alone and in combination with nivolumab in adult subjects with advanced and/or refractory solid tumors, to determine the maximum tolerated dose (MTD) and recommended Phase 2 dose (RP2D), as well as to evaluate preliminary efficacy.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/01/2023
Locations: Sylvester Comprehensive Cancer Center- University of Miami, Miami, Florida
Conditions: Cancer, Melanoma (Skin), Mismatch Repair Deficiency, Microsatellite Instability, Non-melanoma Skin Cancer, Cutaneous Melanoma, NSCLC
Register for Updates
The Use of Functional Electrical Stimulation in Conjunction With Respiratory Muscle Training to Improve Unaided Cough in Individuals With Acute Spinal Cord Injury
NCT05745298
Recruiting
The overall objective of this study is to improve unaided cough with abdominal and latissimus dorsi functional electrical stimulation in conjunction with respiratory muscle training in individuals with acute spinal cord injuries.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/26/2023
Locations: University of Miami, Miami, Florida
Conditions: Acute Spinal Cord Injury
Register for Updates
Motor Plasticity, Intermittent Hypoxia and Sleep Apnea
NCT04017767
Recruiting
The purpose of this study is to learn about the effect of sleep apnea and low oxygen on muscle strength and lung function in people with chronic spinal cord injury.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/26/2023
Locations: University of Miami, Miami, Florida
Conditions: Sleep Apnea, Obstructive, Spinal Cord Injuries, Hypoxia
Register for Updates
A Study to Evaluate Ferumoxytol for the Treatment of Iron Deficiency Anemia (IDA) in Pediatric Subjects
NCT03893045
Recruiting
This is a Phase 3, randomized, open-label, multicenter, study in male and female pediatric subjects (2 years to <18 years of age) with IDA, or felt by their clinician to be at risk of developing IDA. This study allows for enrollment of subjects with IDA regardless of etiology, except for CKD subjects (pediatric CKD subjects are being studied in a separate ferumoxytol protocol).
Gender:
All
Ages:
Between 2 years and 17 years
Trial Updated:
07/25/2023
Locations: Optimus U Corporation, Miami, Florida +1 locations
Conditions: Iron Deficiency Anemia
Register for Updates
A Safety and Pharmacokinetics Study of IDP-122 Lotion in Pediatric Participants With Plaque Psoriasis
NCT03987763
Recruiting
This study is to evaluate the safety, the systemic exposure of halobetasol propionate (HP), and the hypothalamic-pituitary-adrenal (HPA) axis suppression potential for topically applied IDP-122 lotion in pediatric participants with moderate to severe plaque psoriasis.
Gender:
All
Ages:
Between 6 years and 17 years
Trial Updated:
07/25/2023
Locations: Bausch Site 3, Miami, Florida +1 locations
Conditions: Psoriasis
Register for Updates
A Safety and Pharmacokinetics Study of IDP-118 Lotion in Pediatric Participants With Plaque Psoriasis
NCT03988439
Recruiting
This study is to evaluate the safety, the systemic exposure, and the hypothalamic-pituitary-adrenal (HPA) axis suppression potential for topically applied IDP-118 lotion in pediatric participants with moderate to severe plaque psoriasis.
Gender:
All
Ages:
Between 4 years and 17 years
Trial Updated:
07/25/2023
Locations: Bausch Site 8, Miami, Florida
Conditions: Psoriasis
Register for Updates
Trial of Parkinson's And Zoledronic Acid
NCT03924414
Recruiting
This home-based study is a randomized (1:1) placebo-controlled trial of a single infusion of zoledronic acid-5 mg (ZA) for the prevention of fractures in men and women aged 60 years and older with Parkinson's disease and parkinsonism with at least 2 years of follow-up. A total of 3500 participants will be enrolled and randomized in the United States. Participants, follow-up outcome assessors, and study investigators will be blinded to assigned study treatment. This trial is funded by the Nationa... Read More
Gender:
All
Ages:
60 years and above
Trial Updated:
07/24/2023
Locations: Parkinson's Foundation, Miami, Florida +1 locations
Conditions: Parkinson Disease, Osteoporosis, Parkinsonism, Parkinson's Disease and Parkinsonism, Atypical Parkinsonism, Progressive Supranuclear Palsy, Multiple System Atrophy, Vascular Parkinsonism, Dementia With Lewy Bodies
Register for Updates
The ExTINGUISH Trial of Inebilizumab in NMDAR Encephalitis
NCT04372615
Recruiting
Determine the difference in the modified Rankin score at 16 weeks in participants with anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis treated with "first-line" immunomodulatory therapies provided as standard-of-care, and either inebilizumab (investigational agent) or placebo.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/19/2023
Locations: University of Miami, Miami, Florida
Conditions: Autoimmune Encephalitis, Encephalitis
Register for Updates
Developing Strategies for Effective Debridement in Patients for Venous Leg Ulcers
NCT03796793
Recruiting
The goal of this project is to use genomic profiling, candidate genes and proteins to develop guided surgical debridement to improve healing in chronic non-healing venous leg ulcers (VLUs) and to test the efficacy of this approach.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/18/2023
Locations: University of Miami, Miami, Florida
Conditions: Venous Leg Ulcer
Register for Updates
Study to Assess PDM608 in Healthy Adult Subjects
NCT05950906
Recruiting
The purpose of this study is to assess the safety, tolerability and pharmacokinetics of PDM608 in healthy adult subjects.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
07/17/2023
Locations: Quotient Sciences-Miami, Inc, Miami, Florida
Conditions: Parkinson Disease
Register for Updates