There are currently 1293 clinical trials in Miami, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Miami, GSK Investigational Site, University of Miami Miller School of Medicine-Sylvester Cancer Center and University of Miami Miller School of Medicine. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
The University of Miami Adapt (UAdapt) Trial
NCT06111313
Recruiting
The Miami UAdapt Trial is a non-comparative, risk adapted, parallel, randomized, phase 2 study for patients with favorable-intermediate to very high risk non-metastatic prostate cancer with the primary objective of assessing the efficacy and modulation of response of Lattice Extreme Ablative Dose (LEAD) RT with and without androgen deprivation therapy (ADT) at a multidimensional level.
Gender:
MALE
Ages:
Between 35 years and 85 years
Trial Updated:
02/19/2025
Locations: University of Miami, Miami, Florida
Conditions: Prostate Cancer
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Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder
NCT06480383
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled study evaluating the efficacy, safety, and tolerability of ITI-1284 compared with placebo as adjunctive therapy to GAD treatment in patients meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria for GAD who have an inadequate response to ongoing GAD treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: Clinical Site, Miami, Florida +1 locations
Conditions: Generalized Anxiety Disorder
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A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
NCT06540833
Recruiting
This is a multicenter, randomized, double-blind, parallel-group, placebo-controlled, flexible-dose study evaluating the efficacy, safety, and tolerability of ITI-1284 compared with placebo in the treatment of psychosis in patients with AD.
Gender:
ALL
Ages:
55 years and above
Trial Updated:
02/19/2025
Locations: Clinical Site, Miami, Florida +3 locations
Conditions: Psychosis Associated With Alzheimer's Disease
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A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia
NCT06651567
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled, flexible-dose study of the efficacy, safety, and tolerability of ITI-1284 in patients with agitation associated with Alzheimer's dementia
Gender:
ALL
Ages:
55 years and above
Trial Updated:
02/19/2025
Locations: Clinical Site, Miami, Florida +4 locations
Conditions: Agitation Associated With Alzheimer's Dementia
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Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder
NCT06701903
Recruiting
This is a multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy, safety, and tolerability of ITI-1284 as monotherapy treatment in patients meeting Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, Text Revision (DSM-5-TR) criteria for GAD in patients who have had inadequate response to generalized anxiety disorder treatment.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: Clinical Site, Miami, Florida
Conditions: Generalized Anxiety Disorder
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General vs Spinal in Total Joint Arthroplasty (TJA)
NCT06747494
Recruiting
The purpose of this research is to compare post-operative outcomes from patients undergoing TJA. The study team wants to learn about outcomes like length of hospital stay, post-operative pain scores, post-operative nausea, deep and superficial surgical site infection, periprosthetic fracture (a broken bone that occurs around an orthopaedic implant), implant dislocation, readmission rates, and revision rates.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/19/2025
Locations: University of Miami, Miami, Florida
Conditions: Knee Osteoarthritis, Hip Osteoarthritis
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Heated Intraperitoneal Chemotherapy Followed by Niraparib for Ovarian, Primary Peritoneal and Fallopian Tube Cancer
NCT05659381
Recruiting
Patients will be registered prior to, during or at the completion of neoadjuvant chemotherapy (Paclitaxel 175 mg/m2 IV over 3 hours and Carboplatin AUC 6 IV on Day 1 every 21 days for 3-4 cycles). Registered patients who progress during neoadjuvant chemotherapy will not be eligible for iCRS and will be removed from the study. Following completion of neoadjuvant chemotherapy, interval cytoreductive surgery (iCRS) will be performed in the usual fashion in both arms. Patients will be randomized at... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: University of Miami Hospital and Clinics, Miami, Florida +1 locations
Conditions: Stage III Ovarian Cancer, Stage IV Ovarian Cancer, Stage III Primary Peritoneal Cancer, Stage IV Primary Peritoneal Cancer, Stage III Fallopian Tube Cancer, Stage IV Fallopian Tube Cancer
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ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis
NCT05878860
Recruiting
This study will evaluate the safety and tolerability of ATSN-201 in male subjects ≥ 6 years of age with RS1-associated X-linked retinoschisis (XLRS).
Gender:
MALE
Ages:
6 years and above
Trial Updated:
02/18/2025
Locations: Bascom Palmer Eye Institute, Miami, Florida
Conditions: X-linked Retinoschisis
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Study of Tebentafusp and Radioembolization in the Treatment of Metastatic Uveal Melanoma
NCT06627244
Recruiting
The purpose of this study is to determine the effects (good and bad) that Tebentafusp in combination with Yttrium-90 (Y-90) radioembolization has on patients with metastatic uveal melanoma that has spread to the liver.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/18/2025
Locations: University of Miami, Miami, Florida
Conditions: Metastatic Uveal Melanoma, Metastatic Uveal Melanoma in the Liver
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Teclistamab or Talquetamab in Combination with Daratumumab for High-Risk Smoldering Myeloma (REVIVE Study)
NCT06100237
Recruiting
The purpose of this study is to see whether combination treatment of Teclistamab and Daratumumab (Tel-Dara) or combination Talquetamab and Daratumumab (Tal-Dara) will delay the onset of multiple myeloma.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/17/2025
Locations: University of Miami, Miami, Florida
Conditions: Multiple Myeloma
Register for Updates
Chronic Widespread Pain in HIV: Novel Mechanisms and Therapeutics
NCT04787848
Recruiting
To determine if decreased production or release of endogenous opioid peptides by peripheral immune cells contributes to hypersensitivity in people with HIV
Gender:
ALL
Ages:
Between 19 years and 65 years
Trial Updated:
02/15/2025
Locations: Ambulatory Care Center, Florida International University, Miami, Florida
Conditions: Chronic Widespread Pain
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Selinexor, Venetoclax, and Dexamethasone (XVenD) in t(11;14)-Positive Relapsed/Refractory Multiple Myeloma
NCT05530421
Recruiting
The purpose of this research is to determine whether the combination of selinexor, venetoclax, and dexamethasone therapy can increase anti-cancer effects in patients with translocation 11;14-positive (t(11;14)), relapsed/refractory myeloma (RRMM).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/13/2025
Locations: University of Miami, Sylvester Comprehensive Cancer Center, Miami, Florida
Conditions: Relapsed and Refractory Multiple Myeloma
Register for Updates