There are currently 684 clinical trials in Orlando, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including AdventHealth Orlando, GSK Investigational Site, Orlando Clinical Research Center and Nemours Children's Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Efficacy, Safety, and Tolerability of COMP360 in Participants With TRD
NCT05624268
Recruiting
Efficacy, Safety, and Tolerability of a single administration of COMP360 in participants with treatment-resistant depression (TRD)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: Clinical Neurosciecne Solutions, Inc. dba CNS Healthcare, Orlando, Florida +1 locations
Conditions: Treatment Resistant Depression
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Blood Collection for COM/BSBS
NCT06082661
Recruiting
The objective of this biospecimen collection protocol is the acquisition of blood from adult volunteers. These biospecimens will be transferred to the College of Medicine (COM)/Burnett School of Biomedical Sciences (BSBS) research scientists and their research teams for testing according to their separate IRB-approved/exempted protocols. These separate IRBapproved protocols cannot be for genetic testing.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of Central Florida, Orlando, Florida
Conditions: Healthy
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HIV Prevention Intervention for Latino Male Couples
NCT06131931
Recruiting
The primary objective of this proposal is to test the efficacy of Connecting Latinxs en Pareja (CLP). CLP is a four-session intervention grounded in social cognitive theory and a relationship oriented ecological framework. The investigators will examine whether participants assigned to CLP report an increase in the proportion of HIV protected anal sex acts to those assigned to a Wellness Promotion (WP) time and attention matched control condition. The primary outcome, relates to use of HIV prot... Read More
Gender:
MALE
Ages:
Between 18 years and 100 years
Trial Updated:
12/03/2024
Locations: University of Central Florida, Orlando, Florida
Conditions: HIV
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De-identified Human Tissue Project
NCT06082687
Recruiting
Research scientists of the University of Central Florida College of Medicine (COM) and Burnett School of Biomedical Sciences (BSBS) conduct laboratory studies in biomedical and translational medical research for the purpose of understanding human disease and developing innovative methods for diagnosing, measuring, or treating disease or disease symptoms. The key research divisions are cancer, cardiovascular, immunity and pathogenesis, neuroscience, and molecular microbiology.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of Central Florida, Orlando, Florida
Conditions: Tissue
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Crowdsourcing an Open COVID-19 Imaging Repository for AI Research
NCT05384912
Recruiting
The objectives of this project are to (1) assemble a crowdsourced, de-identified radiographic repository; and (2) train and validate existing COVID-NET deep learning diagnostic models.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of Central Florida, Orlando, Florida
Conditions: COVID-19
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Extracellular Vesicles for HD
NCT06082713
Recruiting
The primary objective of this study is to discover blood-based biomarker of brain Huntingtin (HTT) protein using extracellular vesicles to be used in evaluating target engagement in HTT lowering clinical trials. Secondary objectives of this study include developing more accurate biomarkers of Huntington disease (HD) progression or conversion and to develop standard practices for extracellular vesicle biomarker discovery research. The investigators hypothesize that brain-derived extracellular v... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
12/03/2024
Locations: University of Central Florida, Orlando, Florida
Conditions: Huntington Disease
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Rheumatology Diet Study
NCT06339957
Recruiting
This study aims to collect information on rheumatology patients' dietary habits, autoimmune disease activity, dietary changes, disease symptom improvements, and perceptions on their dietary habits and how it affects their autoimmune disease. The main objective is to see if rheumatology patients change their dietary habits after their diagnosis of an autoimmune disease and if it subjectively improved their disease symptoms. It will also look at rheumatology patients' expectations for their rheuma... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
12/03/2024
Locations: UCF Health Clinics, Orlando, Florida
Conditions: Diet Habit, Rheumatologic Disease, Autoimmune Diseases, Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Dermatomyositis/Polymyositis, Sjogren's Syndrome, Systemic Lupus Erythematous, Scleroderma, Fibromyalgia
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Comparing the Effects of Yoga Nidra to Yoga Nidra With Pain Acceptance Intention and Motor Imagery on Pain Outcomes
NCT06590181
Recruiting
Yoga Nidra is a scripted mind-body intervention (MBI) that uses guided relaxation technique in a reproducible sequence of mechanisms that naturally produce a parasympathetic response. This is a randomized controlled trial in which participants will be randomly assigned to one of three interventions: 1) yoga nidra (Yoga Nidra Script Basic), 2) yoga nidra with pain acceptance (Yoga Nidra Acceptance Intention), 3) yoga nidra with pain acceptance and Explicit Motor Imagery (Yoga Nidra Acceptance Int... Read More
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
12/03/2024
Locations: University of Central Florida, Orlando, Florida
Conditions: Chronic Pain
Register for Updates
Contact Registry for Clinical Trials
NCT06084312
Recruiting
The purpose of the Contact Registry for Clinical Trials is to develop a database/listserv of persons interested in clinical trials occurring at the University of Central Florida College of Medicine. Sign up for the UCF College of Medicine's Contact Registry for Clinical Trials to learn about clinical research and clinical trials in areas of interest to you! https://ucf.qualtrics.com/jfe/form/SV_do4WGvKlz4f8Wwe
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of Central Florida, Orlando, Florida
Conditions: This is the Contact Registry
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Tumor-Derived FGF19
NCT06068257
Recruiting
Identify and test thresholds, specificity and sensitivity for a potential cancer associated biomarker protein, FGF19, (and associated markers) for detection in human blood in the blood of breast and colorectal in cancer patients, and see if occurs at higher rates than healthy controls
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: Burnett School Biomedical Sciences, Orlando, Florida
Conditions: Colorectal Cancer, Breast Cancer, Healthy
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Innate Immunity in Allergic Asthma
NCT06068335
Recruiting
The purpose of this study is to determine whether a potential type 2 signature, obtained through stimulation of cell lines with various allergens in vitro, correlates with an allergic or asthmatic disease state ex vivo. This type 2 signature will be multi-hierarchical in nature and will be comprised cell surface receptor expression, pathway activation, and gene upregulation.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
12/03/2024
Locations: University of Central Florida, Orlando, Florida
Conditions: Asthma
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Ferric Citrate and Chronic Kidney Disease in Children
NCT04741646
Recruiting
We will conduct a 12-month, double-blind, randomized, placebo-controlled trial to assess the effects of therapy with ferric citrate (FC) on changes in intact FGF23 levels (iFGF23, primary endpoint) in 160 pediatric patients (80 in each of the two arms) aged 6-18 years of either sex with chronic kidney disease (CKD) stages 3-4 and age-appropriate normal serum phosphate levels. Participants will be randomized to one of the two groups: 1) FC or 2) FC placebo. Participants will be recruited from 20... Read More
Gender:
ALL
Ages:
Between 6 years and 18 years
Trial Updated:
12/03/2024
Locations: Arnold Palmer Hospital for Children, Orlando, Florida
Conditions: Chronic Kidney Diseases
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