There are currently 695 clinical trials in Orlando, Florida looking for participants to engage in research studies. Trials are conducted at various facilities, including AdventHealth Orlando, GSK Investigational Site, Orlando Clinical Research Center and Nemours Children's Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Randomized Trial of EUS-guided Gastrojejunostomy and Surgical Gastrojejunostomy in Gastric Outlet Obstruction
NCT05548114
Recruiting
Malignant gastric outlet obstruction (GOO) results from the mechanical obstruction of the duodenum or distal stomach from an underlying cancer. The consequences of GOO are abdominal pain, nausea, vomiting, anorexia, inability to maintain an oral diet and weight loss, with associated poor quality of life and inability to continue with cancer therapy. The aim of this study is to compare the clinical outcomes between surgical gastrojejunostomy and EUS-guided gastrojejunostomy in patients with malig... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: Orlando Health, Orlando, Florida
Conditions: Gastric Outlet Obstruction
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Crowdsourcing an Open COVID-19 Imaging Repository for AI Research
NCT05384912
Recruiting
The objectives of this project are to (1) assemble a crowdsourced, de-identified radiographic repository; and (2) train and validate existing COVID-NET deep learning diagnostic models.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: University of Central Florida, Orlando, Florida
Conditions: COVID-19
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Tumor-Derived FGF19
NCT06068257
Recruiting
Identify and test thresholds, specificity and sensitivity for a potential cancer associated biomarker protein, FGF19, (and associated markers) for detection in human blood in the blood of breast and colorectal in cancer patients, and see if occurs at higher rates than healthy controls
Gender:
All
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: Burnett School Biomedical Sciences, Orlando, Florida
Conditions: Colorectal Cancer, Breast Cancer, Healthy
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Innate Immunity in Allergic Asthma
NCT06068335
Recruiting
The purpose of this study is to determine whether a potential type 2 signature, obtained through stimulation of cell lines with various allergens in vitro, correlates with an allergic or asthmatic disease state ex vivo. This type 2 signature will be multi-hierarchical in nature and will be comprised cell surface receptor expression, pathway activation, and gene upregulation.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/09/2023
Locations: University of Central Florida, Orlando, Florida
Conditions: Asthma
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Blood Collection for COM/BSBS
NCT06082661
Recruiting
The objective of this biospecimen collection protocol is the acquisition of blood from adult volunteers. These biospecimens will be transferred to the College of Medicine (COM)/Burnett School of Biomedical Sciences (BSBS) research scientists and their research teams for testing according to their separate IRB-approved/exempted protocols. These separate IRBapproved protocols cannot be for genetic testing.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/08/2023
Locations: University of Central Florida, Orlando, Florida
Conditions: Healthy
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CentriMag Failure-to-Wean Post Approval Study
NCT04464785
Recruiting
The primary objective of this Post Approval Study is to report the proportion of patients surviving to 30 days post CentriMag support or to hospital discharge, whichever is longer. For subjects who do not recover and are bridged to a heart transplant or a long-term assist device, the primary endpoint is survival to induction of anesthesia for the surgery.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/05/2023
Locations: Advent Health Orlando, Orlando, Florida
Conditions: Heart Failure
Register for Updates
The Lake Nona Life Project
NCT02533804
Recruiting
The Lake Nona Life Project aims to examine the health and wellness of participants over the course of multiple years, focusing on the links between health and wellness, longevity, quality of life, and human performance.
Gender:
All
Ages:
Between 18 years and 110 years
Trial Updated:
10/03/2023
Locations: Lake Nona Institute, Orlando, Florida
Conditions: Health Behavior, Quality of Life, Aging
Register for Updates
Impact of Exercise Intervention on Well-being in Shift-working Acute Care Nurses
NCT05966805
Recruiting
This is a randomized, wait-list control pilot study to analyze the impact of a 12-week exercise training intervention on post-traumatic growth and whole-person well-being (mental health, physical health, spiritual well-being, perceived social support, and occupational health) among shift-working acute care nurses within AdventHealth.
Gender:
All
Ages:
Between 21 years and 65 years
Trial Updated:
10/02/2023
Locations: AdventHealth, Orlando, Florida
Conditions: Psychological Wellness
Register for Updates
A 52-week, Placebo-controlled Study to Evaluate the Efficacy and Safety of 2 Doses of CHF6001 DPI (Tanimilast), as add-on to Maintenance Triple Therapy in Subjects With COPD and Chronic Bronchitis (PILASTER)
NCT04636801
Recruiting
The purpose of the study is to evaluate the efficacy and safety of two doses of CHF6001 (Tanimilast), as add-on to maintenance triple therapy in the target patient population.
Gender:
All
Ages:
40 years and above
Trial Updated:
10/02/2023
Locations: Chiesi Clinical Trial - Site 840463, Orlando, Florida
Conditions: Chronic Obstructive Pulmonary Disease
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SMR Stemless Reverse vs SMR Reverse Shoulder System
NCT04697004
Recruiting
The SMR Stemless Reverse is intended for total, primary shoulder joint replacement by reducing pain and restoring shoulder articular mobility function. This is a prospective, multi-center, randomized, controlled trial to demonstrate non-inferiority of the SMR Stemless Reverse to the SMR Reverse Shoulder System. Patients with joint dysfunction who continue to experience significant symptoms despite an appropriate course of non-operative management are eligible. Patients will be considered enroll... Read More
Gender:
All
Ages:
22 years and above
Trial Updated:
09/21/2023
Locations: AdventHealth, Orlando, Florida
Conditions: Arthroplasty, Replacement
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A Dose Escalation Study of SHP2 Inhibitor in Patients With Solid Tumors Harboring KRAS of EGFR Mutations
NCT05163028
Recruiting
A Phase 1 dose escalation study in patients with advanced solid tumors harboring KRAS or EGFR mutations to determine the maximum tolerated dose and recommended Phase II dose of HBI-2376 and characterize its pharmacokinetic profile.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/12/2023
Locations: Orlando Health, Inc., Orlando, Florida
Conditions: Non Small Cell Lung Cancer, Colorectal Cancer, Pancreatic Cancer, Solid Tumor, Cancer, Cancer of Pancreas, Cancer of Colon
Register for Updates
A Study of EDP-938 in Non-hospitalized Adults With RSV Who Are at High Risk for Complications.
NCT05568706
Recruiting
This is a Phase 2b, randomized, double-blind, placebo-controlled study of EDP-938 administered orally for the treatment of non-hospitalized adult subjects with confirmed RSV infection who are at high risk for complications after RSV infection.
Gender:
All
Ages:
18 years and above
Trial Updated:
09/12/2023
Locations: Florida Institute For Clinical Research LLC, Orlando, Florida
Conditions: RSV Infection
Register for Updates