Georgia is currently home to 1952 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Atlanta, Augusta, Decatur and Savannah. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Dietary Oxysterols and β-Cell Function Among African Americans
NCT05072587
Recruiting
African Americans (AAs) have a higher risk of developing type 2 diabetes than the general population. AAs are also more likely to eat foods that contain cholesterol oxides/oxysterols. Dietary oxysterols can harm the cells that produce insulin and decrease insulin production. This pilot study seeks to determine if removing dietary oxysterols with a plant-based diet will improve insulin production and decrease the risk of type 2 diabetes among AAs.
Gender:
All
Ages:
18 years and above
Trial Updated:
10/08/2021
Locations: Morehouse School of Medicine, Atlanta, Georgia
Conditions: Type 2 Diabetes
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Continuous Monitoring and Control of Hypoglycemia
NCT03340831
Recruiting
Evaluate safety of non-adjunctive CGM use in CGM naive participants.
Gender:
All
Ages:
2 years and above
Trial Updated:
09/17/2021
Locations: Atlanta Diabetes, Atlanta, Georgia
Conditions: Diabetes
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Myeloma-Developing Regimens Using Genomics (MyDRUG)
NCT03732703
Recruiting
The MyDRUG study is a type of Precision Medicine trial to treat patients with drugs targeted to affect specific genes that are mutated as part of the disease. Mutations in genes can lead to uncontrolled cell growth and cancer. Patients with a greater than 25% mutation to any of the following genes; CDKN2C, FGFR3, KRAS, NRAS, BRAF V600E, IDH2 or T(11;14) can be enrolled to one of the treatment arms. These arms have treatments specifically directed to the mutated genes. Patients that do not have a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/09/2021
Locations: Emory University, Atlanta, Georgia
Conditions: Relapsed Refractory Multiple Myeloma
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The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL
NCT03509961
Recruiting
This study will evaluate the use of non- TBI (total body irradiation) conditioning for B-ALL patients with low risk of relapse as defined by absence of NGS-MRD (next generation sequencing minimal residual disease) before receiving a hematopoietic cell transplant (HCT). Patients diagnosed with B-ALL who are candidates for HCT will be screened by NGS-MRD on a test of bone marrow done before the HCT. Subjects who are pre-HCT NGS-MRD negative will be eligible to receive a non-TBI conditioning regime... Read More
Gender:
All
Ages:
Between 1 year and 25 years
Trial Updated:
08/20/2021
Locations: Children's Healthcare of Atlanta, Atlanta, Georgia
Conditions: B-cell Acute Lymphoblastic Leukemia
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Use of Repris Needle in Bladder Injection
NCT04982120
Recruiting
Treatment of overactive bladder (OAB) has been treated successfully by the injection of Botox. The Repris injection needle has a deflection that may assist in injection difficult to reach with standard straight needles. This study will assess the success, safety and patient tolerance of this new injection needle.
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/28/2021
Locations: Georgia Urology, Cartersville, Georgia
Conditions: Overactive Bladder Syndrome
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Assessment of VMCore Biopsy Versus Standard of Care Biopsy
NCT04982536
Recruiting
Prostate biopsy is the definitive test to establish the diagnosis of prostate cancer. The standard of care biopsy needles do not predictably obtain full cores of tissue and what tissue obtained is often fragmented, making pathologic review a challenge. The VMCore Biopsy System has a geometry in the tip of its biopsy needles that capture more tissue in a single sample. This study is to compare the characteristics of tissue captured by either standard of care needles and the VMCore needle.
Gender:
Male
Ages:
18 years and above
Trial Updated:
07/28/2021
Locations: Georgia Urology, Cartersville, Georgia
Conditions: Prostate Cancer
Register for Updates
Salt and Gut Study
NCT04958148
Recruiting
High sodium intake is a significant risk factor for hypertension. Recently, animal studies connect high sodium intake to the gut-immune axis and highlight the gut microbiome as a potential therapeutic target to counteract salt-sensitive conditions and hypertension. The objective of this project is to determine the effects of high salt intake on gut microbiota composition and gut intestine barrier integrity, leading to increased BP in humans. The investigators also hypothesize that high salt inta... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
06/29/2021
Locations: Georgia Prevention Institute/ Augusta University, Augusta, Georgia
Conditions: High Blood Pressure
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Multi-Center Study to Evaluate the Efficacy and Safety of Sildenafil Cream (3.6%) in Premenopausal Patients With Female Sexual Arousal Disorder
NCT04948151
Recruiting
This study is looking to minimize side effects, while maintaining and potentially improving the therapeutic benefit to patients suffering from Female Sexual Arousal Disorder by providing a topical preparation of Sildenafil locally to the vulvar-vaginal tissue.
Gender:
Female
Ages:
21 years and above
Trial Updated:
06/24/2021
Locations: AGILE Clinical Research Trials, Atlanta, Georgia
Conditions: Female Sexual Arousal Disorder
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An Extension Study to Evaluate the Efficacy and Safety of HORIZANT in Adolescents With Moderate-to-Severe Primary RLS
NCT02633683
Recruiting
The objectives of the trial are to evaluate the long-term efficacy and safety of HORIZANT (Gabapentin Enacarbil) 600 mg daily, for the treatment of RLS in adolescents (13 to 17 years of age) diagnosed with moderate-to-severe primary RLS.
Gender:
All
Ages:
Between 13 years and 17 years
Trial Updated:
06/07/2021
Locations: Clinical Integrative Research Center of Atlanta, INC, Atlanta, Georgia
Conditions: RLS
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Efficacy of a Digestive Enzyme Blend
NCT04917913
Recruiting
The purpose of this study is to investigate the effect of a digestive enzyme supplement (three times per day for 30 days) on gastrointestinal distress (GID) and body composition (body mass and body fat percentage) in healthy men and women (18 - 55 years of age) who experience regular GID (3 - 6 episodes of GID per month).
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
06/01/2021
Locations: Kennesaw State University, Kennesaw, Georgia
Conditions: Digestive Health, Indigestion, Protein Digestion, Carbohydrate Digestion, Fat Digestion, Satiety
Register for Updates
Evaluation of Medtronic DUO Extended Set
NCT04823312
Recruiting
This study is a single-center, non-randomized, prospective single arm study of adult subjects with type 1 diabetes utilizing 670G insulin pump therapy with Continuous Glucose Monitoring (CGM). These subjects will be using 4 DUO Extended sets that will serve as an exploratory pilot study to assess the 7-day survival of the Duo Extended set.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
03/29/2021
Locations: Atlanta Diabetes Associates, Atlanta, Georgia
Conditions: Diabetes Mellitus, Type 1
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Morehouse Total Cancer Care Protocol
NCT04804878
Recruiting
The overall objective of the Morehouse Total Cancer Care study is to develop an improved standard of cancer care by facilitating new biomarker and drug target discovery, informatics solutions, clinical trials, and "personalized medicine" for our community oncology partners (i.e., community hospital systems, and other cancer care providers). To bring new translational research to the community, Morehouse School of Medicine has initiated the Total Cancer Care Program (TCCP). The TCCP establishes a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
03/16/2021
Locations: Morehouse School of Medicine, Atlanta, Georgia
Conditions: Cancer, Cancer Risk
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