Hawaii is currently home to 203 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Honolulu, 'Aiea, Lihue and Kailua. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
NCT01790152
Recruiting
This clinical trial studies the effects of dexrazoxane hydrochloride on biomarkers associated with cardiomyopathy and heart failure after cancer treatment. Studying samples of blood in the laboratory from patients receiving dexrazoxane hydrochloride may help doctors learn more about the effects of dexrazoxane hydrochloride on cells. It may also help doctors understand how well patients respond to treatment.
Gender:
ALL
Ages:
All
Trial Updated:
04/16/2024
Locations: University of Hawaii Cancer Center, Honolulu, Hawaii
Conditions: Hodgkin Lymphoma in Remission, Leukemia in Remission, Lymphoblastic Lymphoma, Osteosarcoma, Recurrent Leukemia, Recurrent Lymphoma, Recurrent Malignant Neoplasm
Register for Updates
S1501 Carvedilol in Preventing Cardiac Toxicity in Patients With Metastatic HER-2-Positive Breast Cancer
NCT03418961
Recruiting
This phase III trial studies how well carvedilol works in preventing cardiac toxicity in patients with human epidermal growth factor receptor (HER)-2-positive breast cancer that has spread to other places in the body. A beta-blocker, such as carvedilol, is used to treat heart failure and high blood pressure, and it may prevent the heart from side effects of chemotherapy.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
04/11/2024
Locations: Pali Momi Medical Center, 'Aiea, Hawaii
Conditions: Cardiotoxicity, HER2/Neu Positive, Metastatic Malignant Neoplasm in the Brain, Recurrent Breast Carcinoma, Stage IV Breast Cancer AJCC v6 and v7
Register for Updates
mHealth to Improve Diet Quality Among Early Adolescents in SNAP-Ed in Hawaii
NCT06360367
Recruiting
The goal of this 8-week clinical trial is to learn whether the PortionSize Ed mobile app helps to improve healthy eating habits among early adolescents in the Hawai'i-Food and Lifeskills for Youth (HI-FLY) program. PortionSize Ed is a dietary assessment and nutrition education mobile app, that provides real-time feedback on adherence to tailored dietary recommendations. HI-FLY is a healthy lifestyle program delivered in schools throughout Hawaii. PortionSize Ed also contains educational videos.... Read More
Gender:
ALL
Ages:
Between 11 years and 14 years
Trial Updated:
04/10/2024
Locations: University of Hawaii at Manoa, Honolulu, Hawaii
Conditions: Diet, Healthy
Register for Updates
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
NCT00736749
Recruiting
This clinical trial keeps track of and collects follow-up information from patients who are currently enrolled on or have participated in a Children's Oncology Group study. Developing a way to keep track of patients who have participated in Children's Oncology Group studies may allow doctors learn more about the long-term effects of cancer treatment and help them reduce problems related to treatment and improve patient quality of life.
Gender:
ALL
Ages:
All
Trial Updated:
04/10/2024
Locations: University of Hawaii Cancer Center, Honolulu, Hawaii
Conditions: Hematopoietic Cell Transplantation Recipient, Leukemia, Solid Tumor
Register for Updates
Metabolism of NNK in Japanese Americans
NCT04228952
Recruiting
The risk of lung cancer varies by individual and by ethnic/racial group. In this study the investigators will explore how individual differences in the metabolism of a tobacco-specific lung carcinogen may contribute to the variable risk of lung cancer between ethnic/racial groups. In this 10 day clinical trial, Japanese Americans will smoke a cigarette containing deuterium-labeled 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific lung carcinogen. The study cigarette will... Read More
Gender:
ALL
Ages:
21 years and above
Trial Updated:
02/27/2024
Locations: University of Hawaii Cancer Center, Honolulu, Hawaii
Conditions: Smoking
Register for Updates
Tension Versus no Tension With Foley Bulb Induction
NCT03588585
Recruiting
To compare the application of tension versus no tension in Foley transcervical catheters for pre-induction cervical ripening.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
02/26/2024
Locations: Kapiolani Medical Center for Women and Children, Honolulu, Hawaii
Conditions: Induction of Labor Affected Fetus / Newborn
Register for Updates
A Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients With Non-alcoholic Fatty Liver Disease (NAFLD), MAESTRO-NAFLD-Open-Label-Extension (MAESTRO-NAFLD-OLE)
NCT04951219
Recruiting
A 52-Week, Multi-center, Open-label, Active Treatment Extension Study to Evaluate Safety and Tolerability of Once Daily, Oral Administration of Resmetirom (MGL-3196)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
11/28/2023
Locations: East-West Medical Research Institute, Honolulu, Hawaii
Conditions: Non-Alcoholic Fatty Liver Disease
Register for Updates
Tigulixostat, Phase 3 Study, Allopurinol Controlled in Gout Patients
NCT05586971
Recruiting
The aim of this 12-month randomized multi-regional double-blind parallel group allopurinol and placebo-controlled phase 3 study is to assess the efficacy and safety of three different doses of Tigulixostat in gout patients with hyperuricemia.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
10/17/2023
Locations: East West Medical Research Institute, Honolulu, Hawaii
Conditions: Gout, Hyperuricemia, Gout Flare, Tophi
Register for Updates
Self-Collected Swabs for Primary Human Papilloma Virus (HPV) Screening
NCT05989464
Recruiting
In this study, the investigators will assess whether implementing a self-swab protocol for primary Human Papilloma Virus (HPV) testing is an effective method to increase cervical cancer screening in a sample of unscreened women in Hawaii. The findings of this study may support adoption of HPV self swab protocols both at Kalihi Palama Health Center (KPHC) and other Federally Qualified Health Centers (FQHC) in Hawaii.
Gender:
FEMALE
Ages:
25 years and above
Trial Updated:
08/23/2023
Locations: Kalihi Palama, Honolulu, Hawaii
Conditions: HPV
Register for Updates
Lesion Composition and Quantitative Imaging Analysis on Breast Cancer Diagnosis
NCT05369546
Recruiting
The objective is to better identify suspicious breast lesions that need to be biopsied for malignancy in women currently recommended for biopsy. The long-term goal is to reduce unnecessary biopsies and increase biopsy yield. To do this, the investigators have developed an innovative way to use FDA-approved breast imaging protocols to acquire multispectral images to measure the composition of suspicious breast lesions. The central hypothesis is that breast tissue composition in combination with a... Read More
Gender:
FEMALE
Ages:
Between 20 years and 85 years
Trial Updated:
01/31/2023
Locations: Hawaii Radiology Associates, LTD (East Hawaii Women's Imaging Center), Hilo, Hawaii
Conditions: Breast Cancer
Register for Updates
Transcutaneous Electrical Nerve Stimulation for Post-Cesarean Pain Control
NCT04399707
Recruiting
Purpose of study is to evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) for post-operative pain control after a cesarean delivery compared to placebo and no TENS.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
05/21/2020
Locations: Nicole Kurata, Honolulu, Hawaii
Conditions: Transcutaneous Electric Nerve Stimulation, Analgesia, Cesarean Section
Register for Updates