There are currently 28 active clinical trials seeking participants for Osteoarthritis research studies. The states with the highest number of trials for Osteoarthritis participants are Florida, California, Texas and Pennsylvania.
Multi-Vendor Multi-Site Novel Accelerated MRI Relaxometry
NCT04536103
Recruiting
Currently the diagnosis of OA is based on radiographs and clinical findings, which is limited to detecting late-stage disease. There is a pressing, unmet clinical need for robust assessment of early changes in cartilage health. Towards this goal, extensive efforts are ongoing to develop quantitative MRI for cartilage matrix analysis. MR T1ρ and T2 relaxation times have shown to be promising imaging biomarkers for early cartilage degeneration and prediction of disease progression. However, many c... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
03/06/2024
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Bone Diseases, Infectious, Musculoskeletal Diseases, Joint Diseases, Osteoarthritis, ACL Tear, Cartilage Degeneration
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Geniculate Artery Embolization for Osteoarthritis
NCT04456569
Recruiting
The need for exploration of more definitive and cost effective non-arthroplasty treatments of osteoarthritis (OA) has been demonstrated by the orthopedic and health economic research. Embolotherapy of neovessels associated with OA joints has been shown to be promising in patients with knee OA. There is a need for level one evidence drawn from randomized clinical trials to prove the safety, feasibility and efficacy of knee embolotherapy compared to standard of care. This randomized pilot study... Read More
Gender:
ALL
Ages:
Between 40 years and 70 years
Trial Updated:
04/15/2025
Locations: University of Minnesota, Minneapolis, Minnesota
Conditions: Osteo Arthritis Knee, Arthritis, Osteoarthritis, Osteoarthritis, Knee
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Ketorolac in Upper Extremity Tendinopathy and Arthropathy
NCT05292339
Recruiting
Osteoarthritis (OA) and inflammatory conditions of the tendons and joints of the shoulder, elbow, hand, and wrist are common yet disabling diseases. Standard management utilizes conservative measures to minimize pain and improve function. Conservative pharmacological management commonly includes corticosteroid and ketorolac injections which have been well investigated as a modality of pain control and improved function in large joint OA. However, fewer studies yielding mixed results on the durat... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/31/2025
Locations: Emory Saint Joseph's Hospital, Atlanta, Georgia +3 locations
Conditions: Osteoarthritis, Tendinopathy, Arthropathy
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Dose Response of Exercise for Arthritis Management
NCT06880653
Recruiting
The purpose of the study is to see examine the effects of 3 different levels of physical activity (45 minutes/week, 90 minutes/week, or 150 minutes/week) on arthritis symptoms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/31/2025
Locations: University of South Carolina, Columbia, South Carolina
Conditions: Arthritis, Rheumatoid Arthritis (RA), Gout, Fibromyalgia (FM), Osteoarthritis, Lupus Erythematosus, Systemic
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Systemic Oral Glucocorticoids for the Treatment of Acute Osteoarthritis Pain in the Emergency Department
NCT06603662
Recruiting
The purpose of this clinical trial is to compare the analgesic effects (relief of pain) of glucocorticoids (steroids) and pain medication versus pain medication alone in adult patients presenting to the emergency department with joint pain due to osteoarthritis. Steroids are drugs that can reduce inflammation and are used commonly for many different medical conditions. In brief, the central aims of the study are to: 1. Assess the efficacy of adding oral glucocorticoid medications to the standa... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/26/2025
Locations: WellSpan York Hospital, York, Pennsylvania
Conditions: Osteoarthritis, Osteoarthritis (OA) of the Knee, Osteoarthritis (OA) of the Shoulder, Osteoarthritis (OA) of the Hip
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SakuraBead Used As Resorbable Embolic for Genicular Artery Embolization
NCT06550024
Recruiting
An open label, prospective, two-arm, multicenter, randomized controlled trial comparing SakuraBead genicular artery embolization (GAE) with a control (corticosteroid injection).
Gender:
ALL
Ages:
Between 40 years and 79 years
Trial Updated:
03/21/2025
Locations: IR Centers, Raleigh, North Carolina +2 locations
Conditions: Osteo Arthritis Knee, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases, Arthritis, Osteoarthritis
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Cemented Vs Cementless Persona Keel RCT
NCT05630053
Recruiting
The main objective of this study is to evaluate the safety, performance, and clinical benefits of the Persona Keel cementless and cemented knee.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
03/21/2025
Locations: Centura Health, Westminster, Colorado +7 locations
Conditions: Knee Pain Chronic, Rheumatoid Arthritis, Osteoarthritis, Traumatic Arthritis, Polyarthritis, Avascular Necrosis, Varus Deformity, Valgus Deformity, Flexion Deformity of Knee
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An Study to Evaluate Safety and Tolerability of OA-SYS in Subjects with Moderate to Severe Osteoarthritis of the Knee Joint
NCT06485843
Recruiting
This study is being conducted to evaluate the safety and tolerability of OA-SYS in patients with moderate to severe OA of the knee joint.
Gender:
ALL
Ages:
Between 35 years and 75 years
Trial Updated:
02/28/2025
Locations: Orthopedic & Sports Medicine Institute of Las Vegas, Las Vegas, Nevada
Conditions: Osteoarthritis, Osteo Arthritis Knee
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Postoperative Hip Precautions After Total Hip Arthroplasty Via the Posterior Approach: a Prospective Randomized Trial
NCT02686528
Recruiting
The purpose of this study is to determine if hip precautions, which are instructions that limit functional use of a hip replacement after surgery, affect the rate of dislocation in the first six weeks after primary total hip replacement surgery. The impact of hip precautions on a patient's return to activities of daily living and overall patient satisfaction will also be investigated. The overall cost effectiveness of hip precautions will be determined.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/25/2025
Locations: Rush University Medical Center, Chicago, Illinois
Conditions: Osteoarthritis, Degenerative Joint Disease
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Sustained Acoustic Medicine for Osteoarthritis Pain
NCT05254574
Recruiting
The purpose of this study is to compare Sustained Acoustic Medicine treatment to topical pain relief gel for the symptomatic management of osteoarthritis. The study will measure pain and function scores for patients undergoing treatment.
Gender:
ALL
Ages:
Between 35 years and 85 years
Trial Updated:
02/24/2025
Locations: James A Haley Veterans Hospital, Tampa, Florida
Conditions: Osteoarthritis
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A Prospective, Clinical Investigation of the Vanguard 360 Revision Knee
NCT01542580
Recruiting
The purpose of this study is to evaluate performance of the Vanguard 360 revision knee system utilizing offset on either the tibial component, femoral component, or both in terms of the restoration of mechanical alignment, clinical outcomes and survivorship.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/20/2025
Locations: Illinois Bone and Joint, Morton Grove, Illinois +11 locations
Conditions: Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Post Traumatic Deformity, Complications; Arthroplasty, Deformity of Limb
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Low Level Laser Therapy (LLLT) for the Treatment of Hand Osteoarthritis.
NCT04692597
Recruiting
This study is a randomized, control trial of Active Duty and DoD Beneficiaries, age 18 years or older, with complaints of hand osteoarthritis. Subjects will be randomized into one of two groups receiving either LLLT or sham LLLT. Subjects will receive LLLT or sham LLLT weekly over a period of six weeks. At each visit, patients will rate their pain using the Defense and Veterans Pain Rating Scale (DVPRS) and assess their functionality using the Disabilities of the Arm, Shoulder, and Hand (DASH) q... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
01/06/2025
Locations: Mike O'Callaghan Military Medical Center, Nellis Air Force Base, Nevada
Conditions: Low Level Laser Therapy, Osteoarthritis, Family Medicine, Pain Management, Integrative Medicine
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