There are currently 2707 clinical trials in Boston, Massachusetts looking for participants to engage in research studies. Trials are conducted at various facilities, including Massachusetts General Hospital, Dana Farber Cancer Institute, Brigham and Women's Hospital and Beth Israel Deaconess Medical Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Forecasting Seizures Using Intelligent Wearable Technology for Health Tracking
NCT06275685
Recruiting
The goal of this interventional study is to develop a personalized seizure risk forecast tool in people with epilepsy. The main questions it aims to answer are: * can we develop a future seizure probabilities tool that is more accurate than chance based on the pattern and frequency of previous generalized tonic-clonic seizure (GTCS) events, as well as changes in physiological and behavioral variables. * does this tool improve the lives of people with epilepsy? Researchers will compare a group... Read More
Gender:
ALL
Ages:
6 years and above
Trial Updated:
09/10/2024
Locations: Empatica, Boston, Massachusetts
Conditions: Epilepsy; Seizure
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YES Study - Newly Diagnosed/Metastatic Intervention
NCT04379414
Recruiting
This research study is being done to monitor common symptoms and behavior, and to provide supportive care information and peer support, as well as research opportunities for young women ages of 18-39 years old who have been diagnosed with stage 0-IV stage breast cancer using a web-based portal (YES), built for smartphones, tablets, and computers.
Gender:
FEMALE
Ages:
Between 18 years and 39 years
Trial Updated:
09/09/2024
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: Breast Cancer, Symptom, Behavioral
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Online Tai Chi Plus Fitbit After ACS
NCT05699642
Recruiting
This projects studies the role of tai chi exercise and wearable fitness trackers to promote physical activity in acute coronary syndrome (ACS) survivors.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/05/2024
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Acute Coronary Syndrome, Physical Inactivity
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Breast Cancer Locator Guided vs. Wire Localized Partial Mastectomy for Breast Cancer
NCT04397185
Recruiting
This prospective, multicenter, 1:1 randomized, controlled trial is designed to evaluate the safety and effectiveness of the Breast Cancer Locator (BCL) in subjects with non-palpable invasive breast cancer or ductal carcinoma in situ (DCIS). Subjects will be randomized to breast conserving surgery (BCS) utilizing either the BCL or wire localization (WL) to guide surgery.
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
09/04/2024
Locations: Tufts Medical Center, Boston, Massachusetts
Conditions: Breast Cancer Female
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Study to Investigate Genetic Causes of Severe Early Childhood Onset Obesity.
NCT01998750
Recruiting
This study aims to investigate genetic causes of early childhood obesity. The investigators will enroll children and adults with severe early onset obesity (BMI \> 99th percentile) diagnosed prior to 6 years of age. The investigators will ask questions about the health and eating behavior of the participants, and perform a brief physical examination. The investigators will collect saliva or blood to perform genetic testing from the participants and invite family members to enroll in the study.
Gender:
ALL
Ages:
80 years and below
Trial Updated:
09/04/2024
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Obesity
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Longitudinal Studies to Identify Biomarkers for Sturge-Weber Syndrome
NCT04717427
Recruiting
Individuals with Sturge-Weber Syndrome (SWS) sometimes have brain involvement which can result in seizures, stroke-like episodes and neurologic deficits. The purpose of this study is to integrate longitudinal clinical data, radiological data, and blood biomarkers of Sturge-Weber syndrome patients. The research aims are: 1. To integrate longitudinal clinical data, radiological data, and blood biomarkers of Sturge-Weber syndrome patients. 2. Identify plasma and imaging biomarkers sensitive to ex... Read More
Gender:
ALL
Ages:
All
Trial Updated:
09/04/2024
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Sturge-Weber Syndrome
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Telephone-based Physical Activity Coaching or Self Monitored Physical Activity to Improve Physical Function in Older Adults Who Are Undergoing Surgery for Lung Cancer and Their Caregivers
NCT06196008
Recruiting
This clinical trial compares telephone-based physical activity coaching to self monitored physical activity for improving physical function in older adults who are undergoing surgery for lung cancer and their caregivers. Lung cancer surgery in older adults is associated with functional declines and unique challenges. Performing physical activity around the time of surgery has been shown to improve functional outcomes in patients and exercise programs delivered via telehealth may improve access a... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/04/2024
Locations: Massachusetts General Hospital (MGH) / Harvard, Boston, Massachusetts
Conditions: Lung Carcinoma
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The PREDICT Registry:
NCT03448926
Recruiting
This is a prospective, non-interventional (observational) cohort study conducted within the medical network of the participating investigators and institutions. Patients meeting the eligibility criteria (see below) will be eligible for participation and the investigators will obtain written informed consent. A central Institutional Review Board (IRB), WCG IRB, will approve the protocol and each participating institution.
Gender:
FEMALE
Ages:
Between 30 years and 85 years
Trial Updated:
09/03/2024
Locations: Dana-Farber Cancer Institute, Boston, Massachusetts
Conditions: DCIS
Register for Updates
North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC)
NCT01694940
Recruiting
The North American Mitochondrial Disease Consortium (NAMDC) maintains a patient contact registry and tissue biorepository for patients with mitochondrial disorders.
Gender:
ALL
Ages:
All
Trial Updated:
09/03/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Mitochondrial Disorders, Mitochondrial Genetic Disorders, Mitochondrial Diseases, Disorder of Mitochondrial Respiratory Chain Complexes, Deletion and Duplication of Mitochondrial DNA
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International Weight Control Registry
NCT04907396
Recruiting
The IWCR is a global scientific study aimed at better understanding the opportunities and barriers for reducing the prevalence of obesity by collecting information from people who have experience with weight management in their everyday lives. The investigators seek to gather information on a wide range of weight management experiences, ranging from weight loss and weight loss maintenance to weight gain and inability to lose weight.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/03/2024
Locations: Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts
Conditions: Weight Loss, Overweight, Obesity
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A Phase I Intravesical PPM Therapy for NMIBC
NCT05519241
Recruiting
This clinical trial is to determine the safety and effectiveness of an investigational bladder cancer drug named "PLZ4-coated paclitaxel-loaded nanoscale micelle (PPM)." PPM is tiny particles that contain the chemotherapy drug paclitaxel. PLZ4 is a molecule that can possibly guide PPM to specifically target and deliver paclitaxel into and kill bladder cancer cells. In this trial, PPM will be instilled into the bladder cavity to treat bladder cancer that does not invade into the muscle layer of t... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/03/2024
Locations: VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA, Boston, Massachusetts
Conditions: Non-muscle-invasive Bladder Cancer
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Developing Restful Environments and Management Strategies for Pediatric Stem Cell Transplant Patients
NCT06468618
Recruiting
Pediatric patients undergoing stem cell transplant (SCT) are hospitalized for extended periods and are at high risk for sleep disturbances. In order to begin to address the environmental issues that SCT recipients face during inpatient hospitalizations, investigators will conduct a single arm pilot study of a program entitled 'Developing Restful Environments and Management Strategies' (DREAMS). The program will provide children receiving SCT and families with information and a kit that includes... Read More
Gender:
ALL
Ages:
Between 9 years and 17 years
Trial Updated:
09/02/2024
Locations: Boston Children's Hospital, Boston, Massachusetts +1 locations
Conditions: Stem Cell Transplant Complications, Sleep Disturbance
Register for Updates