There are currently 2702 clinical trials in Boston, Massachusetts looking for participants to engage in research studies. Trials are conducted at various facilities, including Massachusetts General Hospital, Dana Farber Cancer Institute, Brigham and Women's Hospital and Beth Israel Deaconess Medical Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Hypoglycemia and the Gut Microbiome
NCT03385707
Recruiting
This study is designed to evaluate individuals who are currently experiencing symptoms of hypoglycemia, in order to discern correlations between microbiome composition and patterns of postprandial glycemia.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/10/2023
Locations: Joslin Diabetes Center, Boston, Massachusetts
Conditions: Hypoglycemia
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Extracellular RNA Biomarkers of Duchenne Muscular Dystrophy
NCT05016908
Recruiting
Current methods of measuring the response to new treatments for muscular dystrophies involve the examination of small pieces of muscle tissue called biopsies. The investigators are interested in finding less invasive methods that reduce the need for muscle biopsies. The purpose of this research is to learn about the possibility of detecting and measuring the activity and severity of muscular dystrophies by examining a urine sample and a blood sample.
Gender:
ALL
Ages:
5 years and above
Trial Updated:
10/10/2023
Locations: Boston Children's Hospital, Boston, Massachusetts +1 locations
Conditions: Duchenne Muscular Dystrophy
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Evaluating the Safety and Efficacy of Oral Encapsulated Microbiota Transplantation Therapy in Peanut Allergic Patients
NCT05695261
Recruiting
This is a phase II randomized double-blind placebo-controlled trial that aims at evaluating the safety and tolerability of oral encapsulated fecal microbial transplantation therapy (MTT) in peanut allergic patients. In this research the investigators would like to learn more about ways to treat peanut allergies. The primary objective is to evaluate whether MTT with antibiotic pretreatment can increase the threshold of peanut reactivity during a double-blind placebo-controlled food challenge from... Read More
Gender:
ALL
Ages:
Between 12 years and 17 years
Trial Updated:
10/10/2023
Locations: Boston Children's Hospital, Boston, Massachusetts
Conditions: Allergy, Peanut, Peanut Allergy, Peanut Hypersensitivity, Peanut-Induced Anaphylaxis, Food Allergy, Food Allergy Peanut
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LUT014 for the Reduction of Dose-Limiting Acneiform Lesions Associated With EGFRI Treatment of mCRC
NCT04759664
Recruiting
The study evaluates the efficacy and safety of two strengths of LUT014 Gel topically applied once a day for 4 weeks, compared to placebo, in metastatic colorectal cancer (mCRC) patients who developed Grade 2 or non-infected Grade 3 EGFRI induced acneiform lesions
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/05/2023
Locations: Dana Farber Cancer Institute, Boston, Massachusetts
Conditions: EGFRI Induced Acneiform Lesions
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Extracellular RNA Biomarkers of Myotonic Dystrophy
NCT05020002
Recruiting
Current methods of measuring the response to new treatments for muscular dystrophies involve the examination of small pieces of muscle tissue called biopsies. The investigators are interested in finding less invasive methods that reduce the need for muscle biopsies. The purpose of this research is to learn about the possibility of detecting and measuring the activity and severity of muscular dystrophies by examining a urine sample and a blood sample.
Gender:
ALL
Ages:
5 years and above
Trial Updated:
10/04/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts +1 locations
Conditions: Myotonic Dystrophy
Register for Updates
Biomarker Development for Muscular Dystrophies
NCT05019625
Recruiting
Current methods of measuring the response to new treatments for muscular dystrophies involve the examination of small pieces of muscle tissue called biopsies. The investigators are interested in finding less invasive methods that reduce the need for muscle biopsies. The purpose of this research is to learn about the possibility of detecting and measuring the activity and severity of muscular dystrophies by examining a urine sample and a blood sample, and some muscles in the arms and legs using t... Read More
Gender:
ALL
Ages:
5 years and above
Trial Updated:
10/04/2023
Locations: Boston Children's Hospital, Boston, Massachusetts +2 locations
Conditions: Myotonic Dystrophy, Duchenne Muscular Dystrophy, Becker Muscular Dystrophy, Facioscapulohumeral Muscular Dystrophy
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Gamma-Music Based Intervention for Mild Alzheimer's Disease
NCT05984524
Recruiting
The study will test and refine a novel brain-stimulation tool using gamma-frequency lights coupled with self-selected music for a gamma-music-based intervention for participants with mild Alzheimer's Disease. Results will yield a gamma-stimulation protocol that reliably influences brain activity (Aim 1), is adaptive, motivating and rewarding to use (Aim 2), and will generate predictions as to who might benefit the most from gamma-MBI (Aim 3). By bridging the gap between neurostimulation and beha... Read More
Gender:
ALL
Ages:
Between 50 years and 95 years
Trial Updated:
10/04/2023
Locations: Northeastern University, Boston, Massachusetts
Conditions: Alzheimer Disease
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Psychosocial Mobile App for Chronic Graft-Versus-Host Disease
NCT05690971
Recruiting
The purpose of this research study is to see whether a psychosocial mobile app called Horizons is effective at improving quality of life, symptom burden, psychological distress, and coping in patients living with chronic graft-versus host disease (GVHD)
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/02/2023
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Conditions: Chronic Graft-Versus-Host Disease, Allogeneic Stem Cell Transplant
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Mobile CARE-App to Promote Coping for Caregivers of Patients Receiving Stem Cell Transplant
NCT05709912
Recruiting
The goal of this research study is to determine whether a self-administered, psychosocial mobile application (CARE app) is effective at improving the quality of life and experience of caregivers of patients receiving hematopoietic stem cell transplantation (HCT).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/02/2023
Locations: Massachusetts General Hospital Cancer Center, Boston, Massachusetts
Conditions: Bone Marrow Transplant Complications, Hematologic Malignancy
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Study to Evaluate R2R01 Plus Terlipressin Versus Terlipressin Alone in Patients With Hepatorenal Syndrome
NCT05875948
Recruiting
This study aims to evaluate the safety, tolerability and efficacy of R2R01 combined with terlipressin as compared to terlipressin alone in the treatment of patients with HRS-AKI
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/29/2023
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Hepatorenal Syndrome, Acute Kidney Injury
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Alvimopan Versus Placebo in Patients Undergoing Radical Cystectomy on an Enhanced Recovery Protocol
NCT03216525
Recruiting
To determine if Alvimopan during open or robotic radical cystectomy with urinary diversion results in quicker return of bowel function (GI-2 recovery = time to upper \[first toleration of solid food\] and lower \[first bowel movement\] gastrointestinal recovery) compared to placebo.
Gender:
ALL
Ages:
Between 18 years and 85 years
Trial Updated:
09/26/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Bladder Cancer
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Impact of Intravenous Iron Repletion On Mechanisms of Exercise InTolerance in HFpEF (IRONMET-HFpEF)
NCT04945707
Recruiting
The primary objective of this study is to determine if the correction of functional iron deficiency by administering a single dose of intravenous iron (ferric derimaltose or Monoferric®) in participants with heart failure with preserved ejection fraction (HFpEF) will improve exercise capacity as measured by the change in peak oxygen uptake (peak VO2) from baseline to 12 weeks.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/25/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Iron-deficiency, Heart Failure With Preserved Ejection Fraction
Register for Updates