There are currently 2781 clinical trials in Boston, Massachusetts looking for participants to engage in research studies. Trials are conducted at various facilities, including Massachusetts General Hospital, Dana Farber Cancer Institute, Beth Israel Deaconess Medical Center and Brigham and Women's Hospital. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Proton and Photon Consortium Registry (PPCR): A Multi Center Registry of Pediatric Patients Treated With Radiation Therapy
Recruiting
In previous studies, Proton Beam Radiation Therapy (PBRT) has been found to show better results in treating patients with cancer, both because there is better control of where in the body the radiation is directed and because it is associated with less severe long term side effects. However, there is limited published data demonstrating these results. The goal of the Proton and Photon Consortium Registry (PPCR) is to enroll children treated with radiation in order to describe the population that... Read More
Gender:
All
Ages:
21 years and below
Trial Updated:
01/05/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Pediatric Patients Treated With Radiation Therapy
Role of IL-5R Signaling in Non-eosinophil Upper Airway Cells in CRSwNP
Recruiting
The overarching hypothesis of this proposal is that IL-5 acts on multiple sinus tissue cell types, including plasma cells and epithelial cells, to promote immune dysregulation, and that inhibition of IL-5 affects several relevant effector pathways that lead to clinical benefit.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/04/2023
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Nasal Polyps, Aspirin-exacerbated Respiratory Disease
Study in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Occurring After Total Knee Arthroplasty (TKA)
Recruiting
The purpose of this study is to learn about the safety and effects of PLG0206 for treating periprosthetic joint infections (PJI) in conjunction with the DAIR (debridement, antibiotics and implant retention) surgical procedure for patients with periprosthetic joint infections (PJI) after total knee arthroplasty (TKA) .
Gender:
All
Ages:
Between 18 years and 79 years
Trial Updated:
12/21/2022
Locations: Brigham & Women's Hospital, Boston, Massachusetts
Conditions: Joint Infection
A Mightier Healthcare System
Recruiting
Access to effective pediatric mental health treatment is a major public health concern in the United States as paucity of pediatric providers leading to long wait times, financial burden, and stigma pose significant barriers to treatment. Digital mental health promises to remedy many chronic problems faced in providing timely and accessible mental health interventions to children. With that in mind, the investigators and Neuromotion Inc. created Mightier, an app-based heart rate biofeedback vide... Read More
Gender:
All
Ages:
Between 8 years and 12 years
Trial Updated:
12/20/2022
Locations: Neuromotion Inc, Boston, Massachusetts
Conditions: Emotional Dysregulation
RCT Study to Validate niPGT-A Clinical Benefit.
Recruiting
Chromosomal aneuploidies are linked with spontaneous miscarriages and abnormal offspring in human pregnancies. In addition, some types of aneuploidies are reported to prevent implantation. Thus, there is a need to identify the embryos with highest implantation potential on in vitro fertilization (IVF) programs. Since embryo morphology and kinetics have a weak association with embryo ploidy, trophectoderm biopsy plus Next-Generation Sequencing (NGS) is becoming a very popular approach to determi... Read More
Gender:
Female
Ages:
Between 20 years and 40 years
Trial Updated:
12/13/2022
Locations: Boston IVF Fertility Clinic, Boston, Massachusetts
Conditions: Aneuploidy, Chromosome Abnormality, Infertility
First in Human Phase 1 Ascending Dose Study of PanChol in Healthy Volunteers
Recruiting
This study is a first-in-human, Phase 1 study of the safety, tolerability, and immunogenicity of PanChol in healthy volunteers. There will be three modules in this clinical trial assessing dosing, safety, and immunogenicity: a fixed dose-ranging module, an adaptive dose-finding/optimization module, and a placebo-controlled expansion module.
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
12/11/2022
Locations: Brigham and Women's Hospital Vaccine Unit, Boston, Massachusetts
Conditions: Cholera, Cholera Vaccine Toxicity
Evaluation of an Algorithmically Enhanced Personalized Music-based Intervention on Stress Reduction in Cancer Patients
Recruiting
Receiving a cancer diagnosis is a life-altering event for patients and their families that not only carries serious physical health implications but also causes significant stress and emotional distress. After initial diagnosis, restaging appointments can bring back additional fear, sadness, and anxiety. Music listening interventions can alleviate stress associated with cancer diagnosis by improving patients' ability to cope with the mental and emotional strain that accompanies their disease. Y... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/07/2022
Locations: Saint Elizabeth's Medical Center, Boston, Massachusetts
Conditions: Cancer, Stress
International Weight Control Registry
Recruiting
The IWCR is a global scientific study aimed at better understanding the opportunities and barriers for reducing the prevalence of obesity by collecting information from people who have experience with weight management in their everyday lives. The investigators seek to gather information on a wide range of weight management experiences, ranging from weight loss and weight loss maintenance to weight gain and inability to lose weight.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/07/2022
Locations: Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University, Boston, Massachusetts
Conditions: Weight Loss, Overweight, Obesity
Evaluate F901318 Treatment of Invasive Fungal Infections in Patients Lacking Treatment Options
Recruiting
A study to evaluate F901318 (study drug) for the treatment of invasive fungal infections in patients lacking suitable alternative treatment options.
Gender:
All
Ages:
16 years and above
Trial Updated:
11/30/2022
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Invasive Fungal Infections
Corticosteroids to Treat Pancreatitis
Recruiting
This research is being done to determine if the administration of a short course of intravenous hydrocortisone, an anti-inflammatory medication, to patients with severe acute pancreatitis will improve their clinical outcomes and decrease the length of hospitalization. We think that because inflammation in the body drives the progression of pancreatitis, giving a short course of intravenous hydrocortisone may mitigate disease progression and improve clinical outcomes in patients with severe acute... Read More
Gender:
All
Ages:
Between 18 years and 99 years
Trial Updated:
11/29/2022
Locations: Beth Israel Deaconess Medical Center, Boston, Massachusetts
Conditions: Pancreatitis, Pancreatitis, Acute, Corticosteroid, Hydrocortisone
Computer-based Training of Face Recollection to Improve Face Recognition in Developmental Prosopagnosia
Recruiting
This study will examine the effectiveness of a cognitive training intervention targeting face recollection, repetition lag training, at improving face recognition in Developmental Prosopagnosia.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
11/23/2022
Locations: VA Boston Healthcare System, 150 S. Huntington Ave., Boston, Massachusetts
Conditions: Developmental Prosopagnosia
Evaluation of the Impact of a Forward Viewing Scope at Time of ERCP
Recruiting
This study will be a prospective, tandem-designed study to determine the proportion of clinically significant missed lesions when using a side- or oblique-viewing endoscope as compared to the standard forward-viewing endoscope. Utilizing standard endoscopy protocols in current practice at Brigham and Women's Hospital, consecutive adult patients undergoing ERCP for traditional reasons will undergo back-to-back tandem EGD and ERCP examinations. This process entails an EGD performed by an attending... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/23/2022
Locations: Brigham and Women's Hospital, Boston, Massachusetts
Conditions: Gastro-Intestinal Disorder