There are currently 1093 clinical trials in Rochester, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic - Rochester and Mayo Clinic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Safety and Tolerability of Pirfenidone in Acute Pancreatitis
NCT05350371
Recruiting
The goal of the current pilot clinical trial is to evaluate the safety and tolerability of pirfenidone in patients with predicted moderately severe and severe acute pancreatitis. Pirfenidone is currently approved by FDA for the treatment of idiopathic pulmonary fibrosis. Now, over 5 years of data has accumulated demonstrating safety of its use in humans. The investigators' preclinical data suggest that pirfenidone is very effective in reducing the severity of acute pancreatitis in animal models.... Read More
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
08/28/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Pancreatitis, Acute
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Improving Cardiac Rehabilitation Outcomes Through Mobile Case Management (iCARE)
NCT04938661
Recruiting
The purpose of this research is to find out if doing cardiac rehab at home, or a mix of cardiac rehab at home and in the clinic, is as effective as coming in to the clinic for cardiac rehab.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
08/28/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Acute Myocardial Infarction, Acute Coronary Syndrome, Stable Angina Pectoris, Percutaneous Coronary Intervention, Heart Failure
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Clinical Trial of Concomitant Hip Arthroscopy During PAO
NCT03181048
Recruiting
The study will assess the outcomes of patients treated with concomitant hip arthroscopy at the time of periacetabular osteotomy (PAO) for patients with hip dysplasia compared with patients treated with PAO alone.
Gender:
All
Ages:
Between 15 years and 55 years
Trial Updated:
08/26/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Hip Dysplasia
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Obstructive Sleep Apnea Among Somali-Americans
NCT04124848
Recruiting
The investigators seek to advance the understanding of obstructive sleep apnea as it relates to different ethnic origins as well as sex differences. The investigators will compare Somali patients with known obstructive sleep apnea (OSA) to individuals without OSA, and to individuals of other ethnic/racial origins to determine the risk factors (genetic and/or physiologic) associated with developing cardiovascular diseases. This will help the investigators to understand the unique sleep pathology... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/25/2023
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Obstructive Sleep Apnea
Register for Updates
Study of Disrupted Sleep in Somali Americans
NCT05411029
Recruiting
The aims of this study are to determine the types and severity of previously undiagnosed sleep deficiencies in otherwise healthy Somali Americans, apply a research framework to define psychosocial, behavioral, environmental, and biological mechanisms mediating sleep deficiencies in Somali Americans, and examine the relationship between sleep deficiencies and increased blood pressure in Somali Americans.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
08/25/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Hypertension, Sleep Disorder, Healthy
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iTBS rTMS in Mild Cognitive Impairment
NCT05327257
Recruiting
The purposes of this research are to test whether it is feasible to administer a treatment protocol called intermittent theta burst stimulation (iTBS) repetitive transcranial magnetic stimulation (rTMS) in adults with mild cognitive impairment (MCI), and to test whether iTBS rTMS treatments can improve memory in mild cognitive impairment (MCI).
Gender:
All
Ages:
Between 55 years and 90 years
Trial Updated:
08/23/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Mild Cognitive Impairment
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Group Cognitive Behavior Sessions (CBCSM) to Decrease Distress in Cancer Patients
NCT06015932
Recruiting
This clinical trial tests how well cognitive behavioral cancer stress management (CBCSM) group sessions work to decrease psychological distress in cancer patients. CBCSM teaches patients how to recognize and reduce the impacts of cancer associated stress on the biological, psychological, and social life domains.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/23/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Hematopoietic and Lymphoid System Neoplasm, Malignant Solid Neoplasm
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Study to Evaluate ALIS (Amikacin Liposome Inhalation Suspension) in Participants With Nontuberculous Mycobacterial Lung Infection Caused by Mycobacterium Avium Complex
NCT04677569
Recruiting
The main objective of this study is to evaluate the efficacy of ALIS (amikacin liposome inhalation suspension) + background regimen (azithromycin [AZI] + ethambutol [ETH]) compared to the ELC (empty liposome control) + background regimen on participant-reported respiratory symptoms at Month 13.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/22/2023
Locations: USA013, Rochester, Minnesota
Conditions: Mycobacterium Infections, Nontuberculous
Register for Updates
PDD in Type 2 Diabetes w/wo Diastolic Dysfunction
NCT03744975
Recruiting
This study will advance the investigator's knowledge of the integrated cardiorenal and humoral physiology in type 2 diabetic patients with and without pre-clinical diastolic dysfunction, and test a novel therapeutic strategy which may prevent a progression to symptomatic Stage C heart failure
Gender:
All
Ages:
18 years and above
Trial Updated:
08/22/2023
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Diabetes Mellitus, Type 2, Diastolic Dysfunction
Register for Updates
Rare Kidney Stone Consortium Patient Registry
NCT00588562
Recruiting
The purpose of this study is to collect medical information from a large number of patients in many areas of the world with primary hyperoxaluria (PH), Dent disease, Cystinuria and APRT deficiency. This information will create a registry that will help us to compare similarities and differences in patients and their symptoms. The more patients we are able to enter into the registry, the more we will be able to understand the Primary Hyperoxalurias,Dent disease, cystinuria and APRT and learn bett... Read More
Gender:
All
Ages:
Between 0 years and 100 years
Trial Updated:
08/21/2023
Locations: Dent Disease Registry -Mayo Clinic, Rochester, Minnesota +1 locations
Conditions: Primary Hyperoxaluria, Dent Disease, Cystinuria, APRT Deficiency
Register for Updates
Study of TSR-042, an Anti-programmed Cell Death-1 Receptor (PD-1) Monoclonal Antibody, in Participants With Advanced Solid Tumors
NCT02715284
Recruiting
This is a multi-center, open-label, first-in-human Phase 1 study evaluating the anti-programmed death receptor 1 (anti-PD-1) antibody dostarlimab (also known as TSR-042) n participants with advanced solid tumors who have limited available treatment options. The study will be conducted in 2 parts with Part 1 consisting of safety evaluation, pharmacokinetics (PK), and pharmacodynamics (PDy) of escalating doses of dostarlimab. Dose escalation will be based on ascending weight-based dose levels (DLs... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/18/2023
Locations: GSK Investigational Site, Rochester, Minnesota
Conditions: Neoplasms
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Non-interventional Study on Osilodrostat in Patients With Endogenous Cushing's Syndrome
NCT05382156
Recruiting
This is a non-interventional, multinational, multi-centre study with primary data collection, to further document the safety and efficacy of osilodrostat administered in routine clinical practice in patients treated with osilodrostat for endogenous Cushing's Syndrome
Gender:
All
Ages:
18 years and above
Trial Updated:
08/18/2023
Locations: Mayo Clinic - Rochester, Rochester, Minnesota
Conditions: Endogenous Cushing's Syndrome
Register for Updates