There are currently 1094 clinical trials in Rochester, Minnesota looking for participants to engage in research studies. Trials are conducted at various facilities, including Mayo Clinic, Mayo Clinic in Rochester, Mayo Clinic - Rochester and Mayo Clinic Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Study of TopSpin360 Training Device
NCT06052553
Recruiting
This research is being done to investigate the novel neck strengthening device, TopSpin360 and its effectiveness on measures of neck strength and cognitive function.
Gender:
ALL
Ages:
Between 18 years and 21 years
Trial Updated:
10/11/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Healthy
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Inspiratory Muscle Training in HFpEF
NCT06510231
Recruiting
This study is being done to determine how inspiratory muscle training impacts inspiratory muscle function during exercise in heart failure patients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Heart Failure
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Safety, Tolerability, and Exploratory Efficacy Study of Intrathecally Administered Gene Therapy AMT-162 in Adult Participants with SOD1 Amyotrophic Lateral Sclerosis (SOD1-ALS)
NCT06100276
Recruiting
This is the study of AMT-162 in Participants with SOD1-ALS and is designed to evaluate the safety, tolerability, and exploratory efficacy of intrathecally administered gene therapy AMT-162. AMT-162-001 is a Phase 1/2, multi-center, single ascending dose study.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/08/2024
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Amyotrophic Lateral Sclerosis
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Insulin and Insulin Pulses During Fasting
NCT06424015
Recruiting
Fasting hyperglycemia contributes disproportionately to nonenzymatic glycosylation and the microvascular complications of type 2 diabetes. However, little is known about the regulation of glucose concentrations in the fasting state relative to what is known about the postprandial state. The proposed experiment is part of a series of experiments designed to establish how glucagon and insulin interact with their receptors to control fasting glucose in health and in prediabetes.
Gender:
ALL
Ages:
Between 25 years and 65 years
Trial Updated:
10/07/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: PreDiabetes
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Comparing Use of Incentive Spirometry with and Without Reminder
NCT06101030
Recruiting
This study is designed to determine if patients using an incentive spirometer with visual and auditory signals will increase their use of the incentive spirometer and prevent lung complications.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/03/2024
Locations: Tidal Study Site, Rochester, Minnesota
Conditions: Post Operative
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Use of a Squatting Assist Device in Patients with Constipation
NCT02877394
Recruiting
Constipation is a very common problem. Western style toilets that are nearly universal in the United States require the person to sit on the toilet. However, results from uncontrolled studies suggests that a squatting posture (as prevalent in many foreign countries) may be better at facilitating evacuation compared to a Western style commode. One uncontrolled, unpublished study suggests that a footstool improved bowel symptoms in nearly 98% of 153 constipated participants. Hence, the investigato... Read More
Gender:
FEMALE
Ages:
Between 18 years and 80 years
Trial Updated:
09/30/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Constipation
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Pain Control for Undergoing Costal Cartilage Harvesting
NCT05285566
Recruiting
The purpose of this study is to find out whether injecting the U.S. Food and Drug Administration (FDA) approved drug EXPAREL®, a long acting (approximately 96 hours) numbing medication, will reduce pain after rib cartilage removal in comparison to the standard injection of XYLOCAINE®.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: Mayo Clinic in Rochester, Rochester, Minnesota
Conditions: Nasal Surgery
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A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People with Hairy Cell Leukemia (HCL)
NCT06561360
Recruiting
The researchers are doing this study to compare the safety of vemurafenib in combination with obinutuzumab to the standard of approach of cladribine in combination with rituximab. The researchers will look at which treatment causes fewer or milder side effects. Researchers think vemurafenib and obinutuzumab (non-chemotherapy drugs) may cause fewer side effects compared with the usual approach of chemotherapy drugs. They will also compare the two approaches to see which approach is more effective... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/30/2024
Locations: Mayo Clinic Cancer Center, Rochester, Minnesota
Conditions: Hairy Cell Leukemia
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Effect of Opioid Cessation on Opioid-Induced Esophageal Dysfunction
NCT05854303
Recruiting
The purpose of this study is to evaluate the effect of opioid cessation on opioid-induced esophageal dysfunction (OIED).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/27/2024
Locations: Mayo Clinic Minnesota, Rochester, Minnesota
Conditions: Opioid-Induced Esophageal Dysfunction
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Optimizing Brain Stimulation Parameters
NCT06617845
Recruiting
A primary purpose of this study is to better understand what stimulation parameters work best for patients. For example, for Deep Brain Stimulation (DBS) of the Anterior Nucleus of the Thalamus (ANT), it is not clear what stimulation frequency leads is most effective. This study will help assess the effectiveness of low frequency or high frequency stimulation.
Gender:
ALL
Ages:
6 years and above
Trial Updated:
09/27/2024
Locations: Mayo Clinic Rochester, Rochester, Minnesota
Conditions: Epilepsy; Seizure
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Olorofim Aspergillus Infection Study
NCT05101187
Recruiting
The purpose of this study is to compare treatment with olorofim versus treatment with AmBisome® followed by standard of care (SOC) in patients with IFD caused by proven IA or probable lower respiratory tract disease Aspergillus species (invasive aspergillosis, IA).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
09/26/2024
Locations: Mayo Clinic - Rochester, Rochester, Minnesota
Conditions: Invasive Aspergillosis
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Clinical Trial of Concomitant Hip Arthroscopy During PAO
NCT03181048
Recruiting
The study will assess the outcomes of patients treated with concomitant hip arthroscopy at the time of periacetabular osteotomy (PAO) for patients with hip dysplasia compared with patients treated with PAO alone.
Gender:
ALL
Ages:
Between 15 years and 55 years
Trial Updated:
09/25/2024
Locations: Mayo Clinic, Rochester, Minnesota
Conditions: Hip Dysplasia
Register for Updates