Oregon is currently home to 1258 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Portland, Eugene, Medford and Clackamas. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Directional Versus Nondirectional DBS for ET
Recruiting
This will be a single center (OHSU) proof of concept trial to demonstrate that directional deep brain stimulation (DBS) creates a larger therapeutic window for the treatment of essential tremor (ET), effectively treats ET, and minimizes effects on speech, gait and balance compared to nondirectional DBS.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
03/30/2021
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Essential Tremor
MORE in the Management of Lumbosacral Radiculopathy Symptoms: A Randomized Controlled Trial
Recruiting
INTRODUCTION: Chronic low back pain (CLBP) is a ubiquitous musculoskeletal (MSK) complaint that often presents as a chronic and difficult to treat condition. Lumbosacral radiculopathy/radiculitis (LR) or "sciatica" is a common secondary condition that can last well beyond the expected time frame after treatment with physical therapy, oral anti-inflammatory medications, local steroidal injections, and surgery. Challenges in the treatment of LR indicate that persistent pain may have evolved from m... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
03/25/2021
Locations: National University of Natural Medicine Helfgott Research Institute, Portland, Oregon
Conditions: Lumbar Radiculopathy
To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)
Recruiting
The purpose of the study is to compare the efficacy of parsaclisib when combined with ruxolitinb versus placebo combined with ruxolitinib in participants with myelofibrosis.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/24/2021
Locations: Kaiser Permanente - Northwest, Portland, Oregon
Conditions: Myelofibrosis, Primary Myelofibrosis, Post Essential Thrombocythemia Myelofibrosis, Post Polycythemia Vera Myelofibrosis
Demineralized Bone Matrix Rotator Cuff Study
Recruiting
Patients undergoing rotator cuff repair surgery will experience improved tendon healing with the use of demineralized bone matrix augmentation.
Gender:
All
Ages:
Between 40 years and 75 years
Trial Updated:
12/28/2020
Locations: Southern Oregon Orthopedics, Medford, Oregon
Conditions: Rotator Cuff Injuries
Pragmatic Trial of WHT vs. PC-GE to Promote Non-Pharmacological Strategies to Treat Chronic Pain in Veterans
Recruiting
The overarching goal of this Pain Management Collaboratory Demonstration project is to test a new Whole Health paradigm for chronic pain care, emphasizing non-pharmacological pain self-management that is hypothesized to reduce pain symptoms and improve overall functioning and quality of life in Veterans. In UH3 Aim 1, the investigators will conduct a 12-month pragmatic effectiveness trial at 5 VA sites across the country to test whether veterans with moderate to severe chronic pain randomized to... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
10/21/2020
Locations: VAPHCS, Portland, Oregon
Conditions: Chronic Pain
NBIAready: Online Collection of Natural History Patient-reported Outcome Measures
Recruiting
The purpose of this study is to learn more about Neurodegeneration with Brain Iron Accumulation (NBIA) Disorders. Data is being collected on three types of NBIA disorders: Pantothenate Kinase-Associated Neurodegeneration (PKAN), PLA2G6-associated Neurodegeneration (PLAN) and Beta-propeller Protein-associated Neurodegeneration (BPAN). The study will (1) collect information about how symptoms and findings in NBIA change over time and (2) identify measures of NBIA that can be used in future clinic... Read More
Gender:
All
Ages:
All
Trial Updated:
10/05/2020
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Neurodegeneration With Brain Iron Accumulation (NBIA)
VAPORHCS/OHSU J: MRI and Devices
Recruiting
This is a database study of clinically indicated MRIs on patients with permanent pacemakers and implantable cardioverter defibrillators.
Gender:
All
Ages:
Between 9 years and 99 years
Trial Updated:
10/03/2020
Locations: Oregon Health and Scince University, Portland, Oregon
Conditions: MRI
Study of Crenolanib vs Midostaurin Following Induction Chemotherapy and Consolidation Therapy in Newly Diagnosed FLT3 Mutated AML
Recruiting
A phase III randomized multi-center study designed to compare the efficacy of crenolanib with that of midostaurin when administered following induction chemotherapy, consolidation chemotherapy and bone marrow transplantation in newly diagnosed AML subjects with FLT3 mutation. About 510 subjects will be randomized in a 1:1 ratio to receive either crenolanib in addition to standard first line treatment of AML (chemotherapy and if eligible, transplantation) (arm A) or midostaurin and standard treat... Read More
Gender:
All
Ages:
Between 18 years and 60 years
Trial Updated:
05/21/2020
Locations: Oregon Health and Science University, Portland, Oregon
Conditions: Newly Diagnosed FLT3 Mutated AML
Pulmonary Hypertension Association Registry
Recruiting
The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary Hypertension Care Centers throughout the U.S. PHAR will determine how people with PAH and CTEPH are evaluated, tested, and treated, and will observe how well these participants do. The goal is to see if people with PH a... Read More
Gender:
All
Ages:
All
Trial Updated:
04/01/2020
Locations: The Oregon Clinic, Portland, Oregon
Conditions: Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
Augmentation of Limb Perfusion With Contrast Ultrasound
Recruiting
Our laboratory has discovered that ultrasound (US) imaging together with clinically approved microbubble ultrasound contrast agents can augment limb tissue perfusion. These observations have been made in mice with and without peripheral artery disease (PAD), and also in humans where high power contrast enhanced ultrasound (CEU) was used to measure perfusion but was found also to augment perfusion by almost 2-fold. The latter human studies were performed with ultrasound protocols designed for per... Read More
Gender:
All
Ages:
Between 19 years and 99 years
Trial Updated:
08/21/2018
Locations: OHSU, Portland, Oregon
Conditions: Peripheral Arterial Disease