There are currently 1188 clinical trials in Pittsburgh, Pennsylvania looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Pittsburgh, University of Pittsburgh Medical Center, Alleghany General Hospital and Children's Hospital of Pittsburgh UPMC. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Cerebrovascular Health and Resilience in Midlife
NCT06029348
Recruiting
This study examines cardiovascular responses to a brief psychological challenge under laboratory conditions among adult volunteers. The study volunteers are asked to complete two study sessions. In one session, the volunteers are asked to provide demographic and health-related information via questionnaires and an interview. In that session, volunteers would then be asked to undergo evaluations of their body composition, blood pressure, heart rate, and other signs of cardiovascular function and... Read More
Gender:
ALL
Ages:
Between 40 years and 59 years
Trial Updated:
10/21/2024
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Psychological Stress, Cardiovascular Diseases, Cerebrovascular Disorders
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NEUROCUPLE™ in TKA Patients to Enhance Pain Management
NCT06460350
Recruiting
This is a randomized (1:1) placebo-controlled clinical trial to determine the feasibility and effectiveness of 30-day application of NEUROCUPLE™ patch for pain reduction and opioid consumption following TKA. Results will establish NEUROCUPLE™ as an effective non-opioid postoperative pain management device for FDA approval. Importantly, we have a placebo device (device without the captor array layer) that looks exactly like the active device, allowing us to conduct a true placebo randomized study... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/21/2024
Locations: UPMC Shadyside Hospital, Pittsburgh, Pennsylvania
Conditions: Total Knee Arthroplasty
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Fear of Recurrence and Stopping Immunotherapy
NCT04761328
Recruiting
The study includes participants experiencing distress with regard to stopping immunotherapy and will utilize cognitive-behavioral therapy to reduce fear of recurrence, depression, and anxiety and improve quality of life.
Gender:
ALL
Ages:
21 years and above
Trial Updated:
10/18/2024
Locations: UPMC Hillman Cancer Centers, Pittsburgh, Pennsylvania
Conditions: Cognitive Behavioral Therapy
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Connected Through Coaching for Flourishing Families
NCT06145451
Recruiting
Despite the known association between the quality of participant relational engagement with service providers and clinical outcomes, limited studies have examined caregiver Relational Responsiveness (RR) as a mechanism to achieve maltreatment prevention program outcomes. Using a realist-informed mixed method approach, this study will examine RR's role in mediating the effects of a community-based maltreatment prevention program, the Family Success Network (FSN) on protective factors against malt... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/18/2024
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Maltreatment by Parent
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Cromoglicate Adjunctive Therapy for Outpatients With Schizophrenia
NCT03794076
Recruiting
This is a double blind adjunctive randomized controlled trial for schizophrenia using cromoglicate.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/16/2024
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Schizophrenia, Schizo Affective Disorder
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Exercise-based Program for Rehabilitation of Veterans With Severe Mental Illness
NCT05157620
Recruiting
This is a hybrid1, effectiveness-implementation study of yoga-based exercises (YE) as an adjunctive tool for rehabilitation among persons with Severe Mental Illness (SMI). The two-arm randomized controlled trial will compare the efficacy of YE compared to the Wellness Lifestyle Program (WLP). Primary outcomes of the study will be self-report and performance-based measures of community functioning, defined in the investigators study as social, leisure, employment, and life skills functioning in t... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
10/16/2024
Locations: VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA, Pittsburgh, Pennsylvania
Conditions: Schizophrenia, Schizoaffective, Bipolar Disorder 1
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Biennial CEM in Women with a Personal History of Breast Cancer
NCT06105749
Recruiting
This is a prospective clinical trial that will examine if biennial contrast-enhanced mammography added to annual 3D mammography (tomosynthesis) substantially improves breast cancer detection with minimal increase in false-positives, in women with a personal history of breast cancer.
Gender:
FEMALE
Ages:
Between 30 years and 79 years
Trial Updated:
10/16/2024
Locations: Magee-Womens Hospital, Pittsburgh, Pennsylvania
Conditions: Breast Cancer, Breast Neoplasms, Breast Cancer Female, Neoplasms
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INdividualized Screening Trial of Innovative Glioblastoma Therapy (INSIGhT)
NCT02977780
Recruiting
This research study is studying several investigational drugs as a possible treatment for Glioblastoma (GBM). The drugs involved in this study are : * Abemaciclib * Temozolomide (temodar) * Neratinib * CC115 * QBS10072S
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/15/2024
Locations: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Conditions: Glioblastoma
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The PREDICTOR Study: Assessing Diagnostic Predictors of Airway Collapse in Patients With Obstructive Sleep Apnea
NCT05428839
Recruiting
This study is an exploratory, multicenter study of up to 300 subjects diagnosed with obstructive sleep apnea who are being evaluated for airway surgery. Subjects will undergo standard evaluation for airway surgery as part of standard of care. In addition to the standard airway assessment, a simple, non-invasive measurement of the width of the inside of each subjects mouth will be performed. This measurement takes 2-3 minutes to perform.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/15/2024
Locations: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Conditions: Sleep Apnea, Obstructive
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Bone in CKD Alkali Response (BICARb Pilot Trial)
NCT05918029
Recruiting
The goal of this clinical trial is to test whether potassium citrate improves skeletal health in adults and children with chronic kidney disease. The main questions it aims to answer are: * To evaluate effects of potassium citrate treatment on bone quality and strength. * To evaluate mechanism(s) underlying the effects of potassium citrate on skeletal health. Participants will be asked to: * provide blood, urine and answer questions about health and diet three times during an 8 months period... Read More
Gender:
ALL
Ages:
Between 5 years and 100 years
Trial Updated:
10/11/2024
Locations: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Conditions: Chronic Kidney Diseases, Bone Loss
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Examination of Transcranial Focused Ultrasound on Brain Activity in Adults
NCT06477029
Recruiting
The investigators aim to examine the immediate effect of transcranial focused ultrasound (tFUS) on brain activity in healthy adults.
Gender:
ALL
Ages:
Between 18 years and 45 years
Trial Updated:
10/11/2024
Locations: UPMC, Pittsburgh, Pennsylvania
Conditions: Impulsive Behavior
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Pancreatic Adenocarcinoma Gene Environment Risk Study
NCT00912717
Recruiting
After informed consent, participants will be asked to complete a medical/family history questionnaire and provide a blood sample. Some participants may also be asked to provide a urine sample. Individuals undergoing procedures that require collection of biological samples for clinical purposes may have these samples saved for research purposes. Participants will also be asked for their permission for study investigators to access medical records and/or recontact them for updates to their medical... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
10/10/2024
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Pancreatic Cancer
Register for Updates