There are currently 1191 clinical trials in Pittsburgh, Pennsylvania looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Pittsburgh, University of Pittsburgh Medical Center, Alleghany General Hospital and Children's Hospital of Pittsburgh UPMC. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Offset Mechanisms in Evaluation of Lumbar Medial Branch Blocks
NCT05961800
Recruiting
This study examines the relationship between central nervous system (CNS) mechanisms of pain inhibition and the pain relief that occurs following a lumbar medial branch block (MBB).
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/24/2024
Locations: UPMC St. Margaret, Pittsburgh, Pennsylvania
Conditions: Pain, Chronic, Facet Joint Pain, Pain, Procedural, Analgesia
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Prospective Evaluations of Infectious Complication in Lung Transplant Recipients
NCT00177918
Recruiting
The primary aim of this study is to determine prospectively the viral and C. pneumoniae infection prevalence and outcomes of infections in lung transplant recipients. The study will also determine the correlation of C. pneumoniae infection with the development of obliterans in lung transplant recipients.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/19/2024
Locations: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Conditions: Disorder Related to Lung Transplantation, Bronchiolitis Obliterans
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Treatment, Emotion, and Neuromodulation of Depression (TREND) Study
NCT05436379
Recruiting
The investigators will administer theta burst stimulation (TBS) in efforts to observe a decrease in severity of reported depression symptoms. A subset of participants will receive positive affect training during this intervention.
Gender:
ALL
Ages:
Between 18 years and 26 years
Trial Updated:
07/17/2024
Locations: The University of Pittsburgh, Department of Psychiatry, Pittsburgh, Pennsylvania
Conditions: Depression
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The Effects of Medicaid Policy Interventions on Racial Equity in Severe Maternal Morbidity
NCT05678699
Recruiting
The goal of this study is to learn about the effects of structural inventions, such as equity-focused Medicaid polices, on severe maternal morbidity (SMM) and mortality and maternal health. The main questions it aims to answer are: 1. What is the effect of Medicaid healthcare quality interventions on SMM? 2. What is the effect of Medicaid healthcare quality interventions + doula care? 3. What are Medicaid beneficiaries' experiences in receiving services and the potential impact of integration o... Read More
Gender:
ALL
Ages:
All
Trial Updated:
07/16/2024
Locations: University of Pittsburgh School of Public Health, Pittsburgh, Pennsylvania
Conditions: Severe Maternal Morbidity, Maternal Death
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Clinical Trial for Surgery of the Ulnar Nerve (SUN) at the Elbow
NCT04254185
Recruiting
This research is studying two surgical procedures in a large group of people to learn about how well these procedures work as a treatment for ulnar neuropathy at the elbow (UNE). Researchers want to see which surgery is more helpful for people with ulnar neuropathy. This research will determine if one surgery is better than the other to alleviate symptoms.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2024
Locations: University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
Conditions: Neuropathy Ulnar
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Circadian Rhythms and Homeostatic Sleep Drive and Their Effect on Reward and Cognitive Control Systems in Adolescents
NCT05336084
Recruiting
Adolescence is a time of heightened reward sensitivity and greater impulsivity. On top of this, many teenagers experience chronic sleep deprivation and misalignment of their circadian rhythms due to biological shifts in their sleep/wake patterns paired with early school start times, which may increase the risk for substance use (SU). However, what impact circadian rhythm and sleep disruption either together or independently have on the neuronal circuitry that controls reward and cognition, or if... Read More
Gender:
ALL
Ages:
Between 13 years and 15 years
Trial Updated:
07/10/2024
Locations: Western Psychiatric Hospital, Pittsburgh, Pennsylvania
Conditions: Sleep
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Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia
NCT02735707
Recruiting
REMAP-CAP is a randomised, embedded, multifactorial, adaptive platform trial for community-acquired pneumonia. The purpose of this study is to evaluate the effect of a range of interventions to improve outcome of patients admitted to intensive care with community-acquired pneumonia. In addition, REMAP-CAP provides and adaptive research platform for evaluation of multiple treatment modalities in the event of a respiratory pandemic such as COVID-19. REMAP-COVID is a sub-platform of REMAP-CAP th... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/10/2024
Locations: University of Pittsburgh Medical Centre, Pittsburgh, Pennsylvania
Conditions: Community-acquired Pneumonia, Influenza, COVID-19
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Clinical Trial for Integrated Care to Help At Risk Teen (iCHART) Intervention
NCT05748730
Recruiting
This protocol will test the effectiveness of an intervention, iCHART (integrated Care to Help At-Risk Teens) and facilitate recruitment for other studies in the larger ETUDES Center grant, which are focused on treatment development for target risk factors for suicidal behavior, specifically, sleep, anhedonia, and stress related to cybervictimization. This study will recruit 900 adolescents which will be enrolled in a randomized controlled trial to test iCHART and will be randomized to iCHART or... Read More
Gender:
ALL
Ages:
Between 12 years and 18 years
Trial Updated:
07/08/2024
Locations: UPMC Center for Adolescent and Young Adult Health, Pittsburgh, Pennsylvania
Conditions: Suicide and Depression, Adolescent Behavior
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Eliminating Severe Maternal Morbidity With Heart Health Doulas Trial
NCT05655936
Recruiting
This is a single site, single-blinded parallel randomized control trial that investigates a multi-level intervention to improve postpartum blood pressure in women with hypertensive disorder pregnancy. The investigators will recruit women diagnosed with a hypertensive disorder of pregnancy, identified between 3rd trimester and 2 weeks post-delivery. The investigators will randomize participants to receive usual care home blood pressure monitoring for 6 weeks versus an intervention of usual care +... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/08/2024
Locations: Magee Women's Hospital of UPMC, Pittsburgh, Pennsylvania
Conditions: Preeclampsia, Hypertensive Disorder of Pregnancy, Toxemia, Pregnancy Complications, Hypertension, Pregnancy-Induced, Hypertension, Obesity, Overweight, Nutrition Disorders, Vascular Diseases, Cardiovascular Diseases, Pre-Eclampsia, Eclampsia, Gestational Hypertension
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An Augmented Reality Based System for Neglect Detection, Assessment, and Rehabilitation
NCT04187131
Recruiting
The aim of this phase is to examine the feasibility and acceptability of the Augmented Reality (AR)-based and electroencephalography (EEG)-based neglect detection and rehabilitation tool.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/08/2024
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Stroke
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Early Intervention to Promote Cardiovascular Health of Mothers and Children
NCT06272045
Recruiting
Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) is a cluster randomized clinical trial, funded by the National Heart Lung \& Blood Institute. The study is designed to test the effectiveness of home visiting intervention to promote cardiovascular health and reduce disparities in maternal and early childhood cardiovascular health. Sites, in partnership with evidence-based home visiting programs, are recruiting 6400 participants in total (i.e., 3200 parent-dyads... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/08/2024
Locations: University of Pittsburgh, Pittsburgh, Pennsylvania
Conditions: Cardiovascular Health
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Longitudinal ctDNA Surveillance for Older Women With ER+ Breast Cancer Who Omit Surgery
NCT05914792
Recruiting
This prospective study recruits patients with ER+/HER2-, non-metastatic breast cancer who omit upfront surgery in favor of primary endocrine therapy for sample collection and prospective circulating tumor DNA (ctDNA) measurement to guide disease surveillance.
Gender:
FEMALE
Ages:
70 years and above
Trial Updated:
07/07/2024
Locations: UPMC Magee Womens Hospital - Surgical Oncology, Pittsburgh, Pennsylvania
Conditions: Breast Cancer
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