Mindful Walking Intervention for Physical Inactivity
Recruiting
Mindful walking is a meditation practice that combines physical activity and mindfulness practice. The purpose of this study is to examine the effectiveness of mindfulness-based interventions provided for increasing physical activity among adults with low physical activity levels. A randomized controlled trial design will be utilized, with an intervention and waitlist control group (N = 160). Outcomes measured include physical activity, sleep quality, and functional fitness. Participants will re... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/10/2021
Locations: Clemson University, Clemson, South Carolina
Conditions: Physical Inactivity
Convolutional Neural Network in Ovarian Follicle Identification
Recruiting
A prospective cohort trial studying patients with infertility undergoing an ovarian stimulation with exogenous gonadotropins. Ovarian monitoring will be performed with a combination of transvaginal ultrasound and 2 dimensional human measurements of the follicle development on the right and left ovaries along with SonoAVC. Human and SonoAVC measurements will then be compared to mask region-based convolutional neural network in follicle identification and measurement during during the ovarian stim... Read More
Gender:
Female
Ages:
Between 21 years and 42 years
Trial Updated:
05/05/2021
Locations: Coastal Fertility Specialists, Mount Pleasant, South Carolina
Conditions: Infertility, Female, Ovarian Follicular Cyst
STRIDE Biorepository
Recruiting
The STRIDE Biorepository is an optional substudy available to participants in "Bone Marrow Transplantation vs Standard of Care in Patients with Severe Sickle Cell Disease (BMT CTN 1503) (STRIDE)".
Gender:
All
Ages:
Between 15 years and 40 years
Trial Updated:
02/05/2021
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Anemia, Sickle Cell
Salt-Based E-cigarette
Recruiting
Electronic nicotine delivery systems (ENDS) vary on a wide range of characteristics, which may impact the reinforcement value of the products compared to more harmful combustible products. A new type of low-powered ENDS device has surged in popularity-the pod system. Pods use nicotine salt e-liquids, rather than free-base nicotine solutions that have been used in other ENDS device types. Manufacturers claim that these formulations reduce the harshness of nicotine delivery, while still delivering... Read More
Gender:
All
Ages:
21 years and above
Trial Updated:
01/04/2021
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Smoking, Tobacco Use
An Analysis to Estimate Febrile Neutropenia (FN) in Patients Receiving Udenyca
Recruiting
This is a multicenter, prospective, observational cohort registry in subjects receiving myelosuppressive chemotherapy for a non-myeloid malignancy who are considered to be at high risk for developing febrile neutropenia (FN).
Gender:
All
Ages:
18 years and above
Trial Updated:
12/21/2020
Locations: Coastal Cancer Center, Myrtle Beach, South Carolina
Conditions: Febrile Neutropenia, Non-myeloid Malignancy
Cell-based Assays for Antibody-mediated Transplant Rejection
Recruiting
Goal: The goal of this study is to validate blood tests, which can detect antibody-mediated rejection (ABMR) after renal transplantation. These cell based assays measure CD154-expressing alloantigen-specific B-cells and their subsets in peripheral blood of adult renal transplant recipients. Thirty recipients will be enrolled at two transplant centers, 10 each with ABMR, T-cell mediated rejection (TCMR), and no rejection. Each subject will be sample twice, before and after rejection. Donor-specif... Read More
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
09/21/2020
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Antibody-Mediated Graft Rejection
Efficacy of H7-Coil DTMS Compared to H1-Coil DTMS in Subjects With Major Depression Disorder (MDD)
Recruiting
The purpose of the study is to demonstrate that the efficacy and safety of deep brain rTMS, (Transcranial Magnetic Stimulation) H7-Coil treatment as add on treatment, is as good as the FDA cleared, H1-Coil, in subjects with major depressive disorder that have been previously unsuccessfully treated with antidepressant medications.
Gender:
All
Ages:
Between 22 years and 68 years
Trial Updated:
07/13/2020
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Major Depressive Disorder (MDD)
The Effect of Neuraxial Morphine (Duramorph) on Pain Control
Recruiting
With the rise of the opioid epidemic, it is important for physicians to be more mindful of the amount of narcotic prescriptions that are being written every day. In the early postpartum period, pain and fatigue are the most common problems reported by women. Untreated pain has negative consequences on the amount of opioid narcotics used, postpartum depression, and the potential development of persistent chronic pain. While pain can interfere with a woman's ability to adequately take care of her... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/07/2020
Locations: Augusta University Medical Center, N. Augusta, South Carolina
Conditions: Perineal Tear
Pulmonary Hypertension Association Registry
Recruiting
The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary Hypertension Care Centers throughout the U.S. PHAR will determine how people with PAH and CTEPH are evaluated, tested, and treated, and will observe how well these participants do. The goal is to see if people with PH a... Read More
Gender:
All
Ages:
All
Trial Updated:
04/01/2020
Locations: AnMed Health, Anderson, South Carolina
Conditions: Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
Test and Evaluation of Non-Invasive Neuro-Assessment Devices (NINAD: Neurokinetics, Inc, iPAS
Recruiting
The long term goal for the Traumatic Injury Research Program (TIRP) is testing of novel devices for the identification and longitudinal assessment of traumatic brain injury (TBI). DoD (United States Department of Defense) has now tasked TIRP with the test and evaluation of these devices to assess reliability and validity. The objective of this effort is to test the reliability of the NKI, Inc, (NeuroKinetics, Inc) i-PAS device using a test/re-test protocol with healthy controls. The research de... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
02/12/2020
Locations: The Citadel, Charleston, South Carolina
Conditions: Traumatic Brain Injury, Post Traumatic Stress Disorder
Routine Cardiac Screening in Sarcoidosis Patients
Recruiting
This protocol is an unblended randomized screening trial will have consecutive patients with no suggestion of cardiac sarcoidosis according to usual screening enroll in an enhanced screening protocol. The routine clinical care is to gather patient's history of symptoms and under go an ECG. If a patient has an abnormal results in standard screening, they typically have further evaluations as part of their routine medical care. These tests might include an echocardiogram, ambulatory ECG, and advan... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
08/12/2019
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Sarcoidosis, Cardiac Sarcoidosis, Boeck's Disease, Besnier-Boeck Disease
Trial of Intravenous Fenretinide Emulsion for Patients With Relapsed/Refractory Peripheral T-cell Lymphomas
Recruiting
This study addresses the hypothesis that intermittent treatment with fenretinide intravenous emulsion will induce objective responses in patients with relapsed or refractory Peripheral T-cell Lymphoma (PTCL) who have failed at least one prior systemic therapy and will result in acceptable toxicities.
Gender:
All
Ages:
18 years and above
Trial Updated:
07/22/2019
Locations: Bon Secours Saint Francis Cancer Center, Greenville, South Carolina
Conditions: Peripheral T-cell Lymphoma