South Carolina is currently home to 1231 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Charleston, Greenville, Spartanburg and Columbia. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Trial of Autism Parent Navigator Program
NCT04744428
Recruiting
To address the dual needs of parents for support in navigating Autistic Spectrum Disorder (ASD) services and maintaining positive family functioning, the investigators propose to test Autism Parent Navigators (APN), an innovative in-home, peer support model for parents with a young child recently diagnosed with ASD.
Gender:
All
Ages:
2 years and above
Trial Updated:
11/14/2023
Locations: Family Connections, Columbia, South Carolina
Conditions: Autism Spectrum Disorder
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A Study of Recombinant Von Willebrand Factor (rVWF) in Pediatric and Adult Participants With Severe Von Willebrand Disease (VWD)
NCT03879135
Recruiting
The main aim of the study is to check effectiveness of rVWF (vonicog alfa) prophylaxis based on the annualized bleeding rate (ABR) of spontaneous (not related to trauma) bleeding episodes in pediatric and adult participants during the first 12 months on study treatment. The participants will be treated with rVWF for a maximum of 3 years. Their von Willebrand Disease will be treated according to Investigational product (IP) dosing directions.
Gender:
All
Ages:
All
Trial Updated:
11/14/2023
Locations: Medical University of South Carolina (MUSC), Charleston, South Carolina
Conditions: Von Willebrand Disease (VWD)
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SpHincterotomy for Acute Recurrent Pancreatitis
NCT03609944
Recruiting
The purpose of this study is to determine if a procedure called Endoscopic Retrograde CholangioPancreatography (ERCP) with sphincterotomy reduces the risk of pancreatitis or the number of recurrent pancreatitis episodes in patients with pancreas divisum. ERCP with sphincterotomy is a procedure where doctors used a combination of x-rays and an endoscope (a long flexible lighted tube) to find the opening of the duct where fluid drains out of the pancreas. People who have been diagnosed with pancre... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/14/2023
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Pancreatitis, Pancreas Divisum, Pancreatitis, Acute, Pancreatitis Idiopathic, Pancreas Inflamed
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Quantitative Cardiac Parametric Mapping
NCT02855554
Recruiting
The overall goal of this project is to evaluate the clinical potential of fast quantitative myocardial tissue characterization using recently emerged Cardiac Magnetic Resonance Imaging (CMR) techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases, such as ischemic heart disease, cardiomyopathies, and myocarditis.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
11/14/2023
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Cardiomyopathy, Myocarditis, Ischemic Heart Disease
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Self-Administered 2-Hour Oral Glucose Tolerance Test
NCT06099509
Recruiting
The goal of this randomized controlled trial is to evaluate whether self-administered postpartum diabetes screening tests in patients with gestational diabetes improves screening completion rates. The primary question it aims to answer is: 1. Does a self-administered 75-gram oral glucose tolerance test with virtual follow-up visit increase the rate of postpartum diabetes screening within 12 weeks of delivery?
Gender:
Female
Ages:
18 years and above
Trial Updated:
11/13/2023
Locations: Prisma Health/Greenville Memorial Hospital, Greenville, South Carolina
Conditions: Gestational Diabetes, Postpartum Disorder, Gestational Diabetes Mellitus in Pregnancy
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Monitoring Symptoms to Help Young Women Take Hormone Therapy for Stage I-III Breast Cancer, ASPEN Study
NCT05568472
Recruiting
This phase III trial compares the effect of active symptom monitoring and patient education to patient education alone in helping young women with stage I-III breast cancer stay on their hormone therapy medicines. The patient education tool contains interactive weblinks which provide patients with education material about breast cancer and side effects of therapy. Symptom monitoring is a weblink via email or text message with questions asking about symptoms. Hormone therapy for breast cancer can... Read More
Gender:
Female
Ages:
18 years and above
Trial Updated:
11/09/2023
Locations: AnMed Health Cancer Center, Anderson, South Carolina
Conditions: Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8, Hormone Receptor-Positive Breast Carcinoma
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A Study of Recombinant Von Willebrand Factor (rVWF) With or Without ADVATE in Children With Severe Von Willebrand Disease (VWD)
NCT02932618
Recruiting
The main aim of the study is to check effectiveness, side effects, and tolerability of recombinant von Willebrand Factor (rVWF), with or without ADVATE, in the treatment and control of nonsurgical bleeding events in pediatric participants (less than (<)18 years of age) with severe hereditary von Willebrand disease (VWD). The participants will be treated with rVWF for 12-18 months. Their von Willebrand Disease will be treated by their doctor according to their doctor's usual clinical practice. D... Read More
Gender:
All
Ages:
17 years and below
Trial Updated:
11/09/2023
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Von Willebrand Disease
Register for Updates
rTMS in Older Adults With MCI and AUD
NCT05896332
Recruiting
Alcohol misuse is a risk factor for early onset cognitive impairment, contributing to 10% of early onset dementia, with risk corresponding to consumption. Additionally, continued drinking risks worsening cognitive decline and dementia progression, while worsening cognitive impairment contributes to drinking escalation. Repetitive transcranial magnetic stimulation (rTMS) has been shown to improve cognition in Alzheimer's Disease and Related Dimentias (ADRD) and separately reduce heavy drinking in... Read More
Gender:
All
Ages:
Between 60 years and 85 years
Trial Updated:
11/06/2023
Locations: Medical Univeristy of South Carolina, Charleston, South Carolina
Conditions: Alcohol Use Disorder, Mild Cognitive Impairment, Transcranial Magnetic Stimulation
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A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Oral GSK4172239D Compared With Placebo in Sickle Cell Disease Participants Aged 18 to 50 Years
NCT05660265
Recruiting
This will be a first time in human (FTIH) study in sickle cell diseases (SCD) participants. The FTIH study is planned to evaluate the safety, tolerability, and pharmacokinetics of GSK4172239D. The study will be composed of 3 periods for all participants (Screening, Treatment, and Follow up). Participants will be screened and, prior to first dose on Day 1, will be randomized to receive either GSK4172239D or placebo. GSK4172239D is a prodrug that is converted in vivo into GSK4106401. This study... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
11/06/2023
Locations: GSK Investigational Site, Greenville, South Carolina
Conditions: Hematologic Diseases, Anaemia, Sickle Cell
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MPFC Theta Burst Stimulation as a Treatment Tool for Alcohol Use Disorder: Effects on Drinking and Incentive Salience
NCT04998916
Recruiting
The purpose of this study is to develop transcranial magnetic stimulation (TMS), specifically TMS at a frequency known as theta burst stimulation (TBS), to see how it affects the brain and changes the brain's response to alcohol-related pictures. TMS and TBS are stimulation techniques that use magnetic pulses to temporarily excite specific brain areas in awake people (without the need for surgery, anesthetic, or other invasive procedures). TBS, which is a form of TMS, will be applied over the me... Read More
Gender:
All
Ages:
Between 21 years and 65 years
Trial Updated:
11/06/2023
Locations: Medical University of South Carolina, Charleston, South Carolina
Conditions: Alcohol Use Disorder, Alcohol Drinking, Substance Use, Drinking, Alcohol, Alcohol Use Disorder (AUD)
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Feasibility and ML Training Investigation of the Senseye DT for Diagnosis of Adults With PTSD
NCT05717439
Recruiting
The aim of this study is to obtain data on the feasibility of the Senseye Diagnostic Tool (DT) to assess the presence and severity of post-traumatic stress disorder (PTSD) symptoms. The study will also collect data on Generalized Anxiety Disorder (GAD) and Major Depressive Disorder (MDD) to aid in assessing the presence and severity of these disorders both for the purpose of discerning them from PTSD and determining the feasibility of diagnosing them independently.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/02/2023
Locations: Ralph H. Johnson VA Health Care System, Charleston, South Carolina
Conditions: PTSD, Generalized Anxiety Disorder, Major Depressive Disorder
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Art and Physical Therapy in Pediatric HCT
NCT05441670
Recruiting
The purpose of this study is to compare the effect of a combination of art therapy (AT) and physical therapy (PT) to PT only in children undergoing hematopoietic cell transplant (HCT). Each child will receive daily AT and PT or only PT for 5 days per week for 2 weeks. These sessions will begin approximately on day 15 following the transplant. Prior to starting the sessions and following 2-weeks of sessions, self-care and mobility skills will be measured. During each session, the following variab... Read More
Gender:
All
Ages:
Between 5 years and 18 years
Trial Updated:
10/31/2023
Locations: MUSC Shawn Jenkin's Children's Hospital, Charleston, South Carolina
Conditions: Hematopoietic Stem Cell Transplantation, Art Therapy, Physical Therapy
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