Depression Trials in Texas

A listing of Depression Trials in Texas actively recruiting patient volunteers.

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29 trials found

Optimizing Attentional Bias Modification


Depression has been associated with an attention bias towards negative information. Attention bias modification (ABM) interventions explore potential benefits of training attention away from negative or threatening information and towards neutral or positive information. The goal of this study is to examine the effectiveness of an ABM intervention that includes a preceding mindfulness training among a sample of individuals who self-reported mild-to-moderately depression symptoms. The main questi ...

Conditions: Depression
Phase: Not Applicable

Depression, Experiential Diversity, and Behavioral Novelty


The purpose of the study is to test whether changes in behavioral patterns are related to changes in depression. Depression is a psychological condition that involves persistent sad mood and/or an inability to enjoy pleasurable activities. Very stable behavioral patterns may be related to symptoms of depression. The aim of this study is to learn more about the relationship between symptoms of depression and behavioral patterns that are collected via GPS (global positioning system) location data ...

Conditions: Depression
Phase: Not Applicable

Transdiagnostic Behavioral Therapy for Anxiety and Depression in Autistic Adolescents


This study tests the effectiveness of a transdiagnostic cognitive behavioral therapy for autistic youth with anxiety and/or depression.

Conditions: Anxiety, Depression, Emotional Disorder, Autism
Phase: Not Applicable

Evaluation of a Therapeutic Mobile App for Depression


The purpose of this study is a preliminary evaluation of a gamified attention bias modification training (GAMBT) for reducing symptoms of depression and rumination. Individuals with elevated symptoms of depression will use the digital intervention over the course of 4 weeks. They will complete a brief (~5 question) survey daily, as well as weekly assessments.

Conditions: Depression
Phase: Not Applicable

Exploring Virtual Reality Adventure Training Exergaming


The current project aims to design and implement an 8-week Virtual Reality Adventure Therapy Exergaming (V-RATE) intervention focused on women veterans. A randomized controlled trial using a repeated measure design with a 1-month follow-up assessment will be employed to examine effects on physical and mental health outcomes.

Conditions: Physical Activity, Sedentary Behavior, Depression, Cognitive Function, Post Traumatic Stress Disorder, Quality of Life, Heart Rate Variability, Anxiety
Phase: Not Applicable

Functional Connectivity Alterations in Suicidal Patients Among Opioid Users


Suicide is the 10th leading cause of death for Americans of all ages and more people in the United States now die from suicide than die from car accidents. Although death by firearm remains the most common cause of suicide in the United States, an intentional overdose of substance usage such as prescription opioids accounts for over 5,000 suicides per year. In 2017, more than 70,000 drug overdose deaths occurred, making it the leading cause of injury-related death, and well over half (67.8%) inv ...

Conditions: Substance Abuse, Suicide, Depression
Phase: Not Applicable

Combination Therapy for Treatment of Sleep Disturbance in Patients With Advanced Cancer


To learn if Cognitive Behavior Therapy (called CBT), combined with either Bright Light Therapy (called BLT), methylphenidate, and/or melatonin, can help improve sleep and other related symptoms such as fatigue, anxiety, and depression in cancer patients. This is an investigational study. In this study, BLT, Methylphenidate and Melatonin will be compared to their placebos.

Conditions: Sleep, Fatigue, Anxiety, Cancer, Depression
Phase: Phase 2/3

Reducing Sleep disTurbance in Cancer


In a randomized controlled trial (RCT), the investigators will recruit participants to an 8-week "app-based wellness" intervention: the active daily meditation intervention (Calm) or the health education podcast control group (POD), followed by a 12-week follow-up period. The investigators will recruit a total of 276 self-declared Chronic Hematological Cancer (CHC) patients who (representative of age, race/ethnicity, and gender) will be on stable CHC pharmacologic therapy (if any), self-identify ...

Conditions: Cancer, Sleep Disturbance, Anxiety, Depression, Inflammation, Fatigue
Phase: Not Applicable

Behavioral Activation Plus Savoring for University Students


The current investigation aims to examine whether a brief, two-session, virtual behavioral activation plus savoring intervention will increase daily positive emotion in university students.

Conditions: Mood, Anhedonia, Depression
Phase: Not Applicable

Focused Ultrasound Amygdala Neuromodulation


The purpose of the study is to examine the feasibility and potential efficacy of low-intensity focused ultrasound as a method of modulating amygdala function to promote improvements in symptoms of an affective disorder. Ultrasound is frequently and safely utilized for diagnostic purposes. In this study, the investigators will utilize magnetic resonance imaging (MRI) and neuronavigation to target the left amygdala and apply ultrasound. This will be conducted once a day, 5 days a week, for 3 weeks ...

Conditions: Depression, Anxiety Disorders, Bipolar Depression, Ptsd

The PATHway Study: Primary Care Based Depression Prevention in Adolescents


Prevention of depressive disorders has become a key priority for the NIMH, but the investigators have no widely available public health strategy to reduce morbidity and mortality. To address this need, the investigators developed and evaluated the primary care based-technology "behavioral vaccine," Competent Adulthood Transition with Cognitive-Behavioral Humanistic and Interpersonal Therapy (CATCH-IT). The investigators will engage N=4 health systems representative of the United States health ca ...

Conditions: Depression, Mental Disorder in Adolescence
Phase: Not Applicable

Affect Treatment for Depression and Anxiety


The purpose of this study is to evaluate the efficacy and mediators of change in Positive Affect Treatment, a psychotherapy specifically aimed at enhancing reward sensitivity in individuals with low positive affect (a core feature of anhedonia) in the context of depression or anxiety. Target enrollment is 100 male and female participants with low positive affect and depression or anxiety and impaired functioning, between the ages of 18 and 65 years, who will be randomized to either Positive Aff ...

Conditions: Depression, Anxiety
Phase: Not Applicable