There are currently 1547 clinical trials in Dallas, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including University of Texas Southwestern Medical Center, UT Southwestern Medical Center, UT Southwestern/Simmons Cancer Center-Dallas and GSK Investigational Site. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Proof of Principle Study to Evaluate the Safety, PK, Viral Shedding and Efficacy of Pentarlandir™ UPPTA for Patients With Early COVID-19
NCT04911777
Recruiting
This is a clinical trial to evaluate the safety, PK, viral shedding and clinical effects of Pentarlandir™ UPPTA in patients with early COVID-19. Approximately 90 ambulatory subjects with mildly symptomatic early COVID-19, who have been diagnosed with COVID-19 within the prior 4 days will be enrolled.
Gender:
All
Ages:
Between 18 years and 64 years
Trial Updated:
12/16/2021
Locations: Elite Medical Research, Dallas, Texas
Conditions: Coronavirus Disease 2019
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Evaluating the Effect of Itraconazole on Pathologic Complete Response Rates in Esophageal Cancer
NCT04018872
Recruiting
Esophageal cancer, which has a low 5-year overall survival rate for all stages (<20%) , is increasing in incidence. Previous studies have shown that the Hedgehog (Hh) and AKT signaling pathways are activated in a significant proportion of esophageal cancers. Itraconazole, a widely used anti-fungal medication, has been shown to inhibit various pathways involved in esophageal cancer tumorigenesis including Hh and AKT. In this phase II clinical trial, the investigators aim to evaluate the effect of... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
11/02/2021
Locations: Dallas VA Medical Center, Dallas, Texas
Conditions: Esophagus Adenocarcinoma, Esophagus Squamous Cell Carcinoma, Gastroesophageal Junction Adenocarcinoma
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Continuous Monitoring and Control of Hypoglycemia
NCT03340831
Recruiting
Evaluate safety of non-adjunctive CGM use in CGM naive participants.
Gender:
All
Ages:
2 years and above
Trial Updated:
09/17/2021
Locations: Research Institute of Dallas, Dallas, Texas
Conditions: Diabetes
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Myeloma-Developing Regimens Using Genomics (MyDRUG)
NCT03732703
Recruiting
The MyDRUG study is a type of Precision Medicine trial to treat patients with drugs targeted to affect specific genes that are mutated as part of the disease. Mutations in genes can lead to uncontrolled cell growth and cancer. Patients with a greater than 25% mutation to any of the following genes; CDKN2C, FGFR3, KRAS, NRAS, BRAF V600E, IDH2 or T(11;14) can be enrolled to one of the treatment arms. These arms have treatments specifically directed to the mutated genes. Patients that do not have a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/09/2021
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Relapsed Refractory Multiple Myeloma
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Foundational Ingredients of Robotic Gait Training for People With Spinal Cord Injury During Inpatient Therapy
NCT04781621
Recruiting
The FIRST project compares the dose of robotic gait training (RGT) with usual care gait training for patients with spinal cord injury (SCI) undergoing rehabilitation at Baylor Scott & White Institute for Rehabilitation (BSWIR).
Gender:
All
Ages:
Between 16 years and 70 years
Trial Updated:
06/30/2021
Locations: Baylor Scott & White Institute for Rehabilitation, Dallas, Texas
Conditions: Spinal Cord Injuries
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Observational Study to Compare Outcomes of Different Psychiatric Treatment of Suicidal Adolescents
NCT04625686
Recruiting
To address the unmet need of optimizing the treatment and management for adolescent suicidality, the investigators propose to evaluate the effectiveness and safety of telehealth services compared to inpatient and OCIC for suicidal adolescents in target population. To achieve this goal, the investigators propose a multi- site study to compare telehealth, OCIC, and inpatient care, and see which can lead to a lower risk of a suicidal event (primary outcome) as well as higher treatment satisfaction... Read More
Gender:
All
Ages:
Between 12 years and 18 years
Trial Updated:
04/26/2021
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Suicidal Ideation
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Veteran Affairs Osteoarthritis Knee Study
NCT04698733
Recruiting
A clinical study at the Dallas Veterans Affairs, is being proposed to test the efficacy of a novel electrical stimulation platform named the Pro-Sport Ultra® device by AVAZZIA to reduce pain and increase activity level in patients with knee osteoarthritis.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
03/04/2021
Locations: Veteran Affairs North Texas Healthcare System, Dallas, Texas
Conditions: Knee Osteoarthritis
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DWIBS-MRI: An Adjunct to the Traditional Diagnostic Breast Imaging Evaluation
NCT04491864
Recruiting
1.1. Primary Objectives To determine if MRI DWIBS can accurately identify suspicious lesions previously categorized on mammography and sonography as potentially malignant. We will also validate whether DWIBS-MRI ADC values can be used to accurately differentiate benign from malignant lesions. Additionally, because it is not known whether tumor type or growth rate (Ki67 values) will affect our results, we will include these parameters in our analysis. Once we validate the use of DWIBS-MRI ADC va... Read More
Gender:
Female
Ages:
30 years and above
Trial Updated:
07/27/2020
Locations: Baylor Scott & White Research Insitute, Dallas, Texas
Conditions: Breast Cancer
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Gastroesophageal Reflux Disease Prospective Registry
NCT02479438
Recruiting
The purpose of this registry is to evaluate information to determine which operations and treatments for gastroesophageal reflux disease or similar diseases of the stomach, esophagus or digestive tract are providing the most benefit including the long-term effects of treatment (or no treatment) and the progression of the disease over time.
Gender:
All
Ages:
18 years and above
Trial Updated:
06/26/2020
Locations: Baylor Research Institute, Dallas, Texas
Conditions: GERD
Register for Updates
Pulmonary Hypertension Association Registry
NCT04071327
Recruiting
The PHA Registry (PHAR) is a national study about people who have pulmonary arterial hypertension (PAH) and chronic thromboembolic pulmonary hypertension (CTEPH). PHAR collects information from people with PAH and CTEPH who are cared for in participating PHA-accredited Pulmonary Hypertension Care Centers throughout the U.S. PHAR will determine how people with PAH and CTEPH are evaluated, tested, and treated, and will observe how well these participants do. The goal is to see if people with PH a... Read More
Gender:
All
Ages:
All
Trial Updated:
04/01/2020
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Pulmonary Arterial Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Hypertension
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SOLEMN Study - Synergy Optical Coherence Tomography in Left Main PCI
NCT03474432
Recruiting
BACKGROUD: Percutaneous coronary intervention (PCI) is increasingly used to treat unprotected left main coronary artery stenosis. Protected LM PCI is considered standard of care in most centers. OCT allows for precise determination of stent placement, stent expansion and apposition. The pattern of vessel healing can be very precisely studied if immediate post-stent implantation OCT/IVUS data is compared to the 6-month post-PCI interval. While OCT cannot be optimally used for ostial lesion ima... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
01/14/2019
Locations: Dallas VA Medical Center, Dallas, Texas
Conditions: Percutaneous Coronary Intervention, Optical Coherence Tomography, In-stent Coronary Artery Restenosis
Register for Updates