There are currently 2862 clinical trials in Houston, Texas looking for participants to engage in research studies. Trials are conducted at various facilities, including M D Anderson Cancer Center, University of Texas MD Anderson Cancer Center, Baylor College of Medicine and The University of Texas - MD Anderson Cancer Center. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
EPPIC-Net: Platform Protocol to Assess Treatments for Painful Diabetic Peripheral Neuropathy
NCT05476276
Recruiting
This is a Platform Protocol to perform Phase II clinical trials in The Early Phase Pain Investigation Clinical Network (EPPIC-Net), under The Helping to End Addiction Long-termSM Initiative, or NIH HEAL InitiativeSM, related to the treatment of Painful Diabetic Peripheral Neuropathy (PDPN) in a platform setting to test multiple assets under a single protocol.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/20/2024
Locations: Nerve and Muscle Center of Texas, Houston, Texas
Conditions: Painful Diabetic Neuropathy
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High Dose Testosterone for ATM, CDK12 or CHEK2 Altered Prostate Cancers
NCT05011383
Recruiting
This study will determine whether the presence of DNA repair deficiency in the form of alterations in the genes ATM, CDK12 or CHEK2 predicts for a high likelihood of responding to the use of intermittent high dose testosterone. This therapy may result in responses in tumors which are genetically unstable because of DNA repair deficiency and this is a prospective study to test that hypothesis
Gender:
MALE
Ages:
18 years and above
Trial Updated:
08/19/2024
Locations: Michael E. DeBakey VA Medical Center, Houston, TX, Houston, Texas
Conditions: Metastatic Prostate Cancer
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Childhood Cancer Survivor Study
NCT01120353
Recruiting
The Childhood Cancer Survivor Study (CCSS) will investigate the long-term effects of cancer and its associated therapies. A retrospective cohort study will be conducted through a multi-institutional collaboration, which will involve the identification and active follow-up of a cohort of approximately 50,000 survivors of cancer, diagnosed before 21 years of age, between 1970 and 1999 and 10,000 sibling controls. This project will study children and young adults exposed to specific therapeutic mod... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/19/2024
Locations: M.D. Anderson Cancer Center, Houston, Texas +1 locations
Conditions: Cancer
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APG-2575 Study of Safety, Tolerability ,PK/PD in Patients With Hematologic Malignancies
NCT03537482
Recruiting
This is a multi-center, single-agent, open-label, Phase I study of APG-2575. The study consists of the dose escalation stage and the dose expansion stage.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/16/2024
Locations: MDACC, Houston, Texas
Conditions: Hematologic Malignancies
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A Study Evaluating APG-115 as a Single Agent or in Combination With APG-2575 in Subjects With R/R T-PLL and NHL
NCT04496349
Recruiting
The goal of this study is to evaluate the pharmacokinetics (PK), safety, and efficacy of APG-115 as a single agent or in combination with APG-2575 in patients with T-PLL and NHL.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/16/2024
Locations: MD Anderson, Houston, Texas
Conditions: T-Prolymphocytic Leukemia, Non-Hodgkins Lymphoma
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Cetuximab for the Treatment of Advanced Unresectable or Metastatic Chordoma
NCT05041127
Recruiting
This is a multicenter, single arm, phase 2 study designed to evaluate the efficacy and safety of cetuximab for the treatment of advanced (unresectable)/metastatic, chordoma. The target patient population will be any chordoma patient 18 years of age with locally unresectable disease or metastatic disease.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/16/2024
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Metastatic Chordoma, Unresectable Chordoma, Chordoma
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Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial
NCT05991453
Recruiting
The investigators will conduct a 12,500-patient randomized multi-center trial to determine (i) which general anesthesia technique yields superior patient recovery experiences in any of three surgical categories ((a) major inpatient surgery, (b) minor inpatient surgery, (c) outpatient surgery) and (ii) whether TIVA confers no more than a small (0.2 %) increased risk of intraoperative awareness than INVA in patients undergoing both outpatient and inpatient surgeries
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/15/2024
Locations: University of Texas - MD Anderson, Houston, Texas
Conditions: Surgery-Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Anesthesia Morbidity
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Transcutaneous Tibial Nerve Stimulation for Spinal Cord Injury Neurogenic Bladder
NCT04350359
Recruiting
The purpose of this study is to determine if electric stimulation to the leg, called transcutaneous tibial nerve stimulation (TTNS), can improve bladder outcomes in acute spinal cord injury.
Gender:
ALL
Ages:
Between 18 years and 75 years
Trial Updated:
08/15/2024
Locations: TIRR Memorial Hermann Research Center, Houston, Texas
Conditions: Spinal Cord Injuries
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Blue Light Cystoscopy With Cysview® Registry
NCT02660645
Recruiting
Registry study to gather more information on the current use of Blue Light Cystoscopy with Cysview (BLCC) in urologists' practices.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2024
Locations: Michael E. DeBakey VA Medical Center, Houston, Texas
Conditions: Bladder Cancer
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Study of Selected X-Linked Disorders: Aicardi Syndrome
NCT00697411
Recruiting
Based on our current understanding of Aicardi syndrome, the condition is hypothesized to occur due to a genetic change on the X-chromosome. The research team is investigating Aicardi syndrome to identify the specific gene location associated with the disorder. The investigators are collecting blood and skin biopsy samples from patients and their parents. A permanent cell line is prepared and DNA from the blood and skin samples and cell lines is isolated and then used for genetic testing. The cur... Read More
Gender:
ALL
Ages:
All
Trial Updated:
08/14/2024
Locations: Baylor College of Medicine, Houston, Texas
Conditions: Aicardi Syndrome, Brain Disorders
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Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
NCT04510597
Recruiting
This phase III trial compares the effect of adding surgery to a standard of care immunotherapy-based drug combination versus a standard of care immunotherapy-based drug combination alone in treating patients with kidney cancer that has spread to other places in the body (metastatic). Immunotherapy with monoclonal antibodies, such as nivolumab, ipilimumab, pembrolizumab, and avelumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow an... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
08/14/2024
Locations: Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas +1 locations
Conditions: Metastatic Clear Cell Renal Cell Carcinoma, Metastatic Renal Cell Carcinoma, Stage IV Renal Cell Cancer AJCC v8
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Evaluating the Relationship Between Skin Color and Pulse Oximeter Accuracy in Children
NCT06529575
Recruiting
This multisite study seeks to understand whether and how pulse oximeter accuracy varies across children with different skin colors in real world clinical settings. Many factors can affect how well pulse oximeters work; for example, movement and even fingernail polish. Some studies in adults show that skin color may also affect the pulse oximeter reading. In this study, we will explore pulse oximeter accuracy in children of all skin colors who are undergoing cardiac catheterizations. The study wi... Read More
Gender:
ALL
Ages:
Between 4 weeks and 18 years
Trial Updated:
08/14/2024
Locations: Texas Children's Hospital, Houston, Texas
Conditions: Pediatric ALL, Cardiac Defect
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