Texas is currently home to 5010 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study to Assess BOTOX Injections for the Change of Masseter Muscle Prominence in Adult Participants
Recruiting
The masseter muscle is one of the muscles in the lower face used for chewing. The prominence of the masseter muscle can appear as a widened lower face which some individuals deem as aesthetically undesirable and can be treated by selectively weakening the masseter muscles with small quantities of botulinum toxin. The purpose of this study is to assess how safe and effective injection of onabotulinumtoxinA (BOTOX) is in adult participants with Masseter Muscle Prominence (MMP). BOTOX is being inv... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Austin Institute for Clinical Research at SBA Dermatology /ID# 248228, Houston, Texas
Conditions: Masseter Muscle Prominence
A Study to Assess BOTOX Injections in Adult Participants for the Change of Masseter Muscle Prominence
Recruiting
The masseter muscle is one of the muscles in the lower face used for chewing. The prominence of the masseter muscle can appear as a widened lower face which some individuals deem as aesthetically undesirable and can be treated by selectively weakening the masseter muscles with small quantities of botulinum toxin. The purpose of this study is to assess how safe and effective injection of onabotulinumtoxinA (BOTOX) is in adult participants with Masseter Muscle Prominence (MMP). BOTOX is being inv... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Austin Institute for Clinical Research /ID# 248217, Pflugerville, Texas
Conditions: Masseter Muscle Prominence
A Study of Barzolvolimab in Patients With Prurigo Nodularis
Recruiting
The purpose of this study is to assess the efficacy and safety of barzolvolimab in adults with prurigo nodularis.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Center for Clinical Studies, Webster, Texas
Conditions: Prurigo Nodularis
Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia
Recruiting
This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with hypertriglyceridemia (HTG). After providing informed consent eligible participants will be randomized to receive 4 doses (once every 3 months) of plozasiran or placebo and be evaluated for efficacy and safety.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Juno Research LLC, Houston, Texas
Conditions: Hypertriglyceridemia
Study of Plozasiran in Adults With Severe Hypertriglyceridemia
Recruiting
This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with severe hypertriglyceridemia (SHTG). After providing informed consent eligible participants will be randomized to receive 4 doses (once every 3 months) of plozasiran or placebo, and be evaluated for efficacy and safety. After Month 12, eligible participants will be offered an opportunity to continue in an optional open-label extension under a separate protocol.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Juno Research LLC, Houston, Texas
Conditions: Severe Hypertriglyceridemia
A Study to Assess the Safety and Efficacy of Oral Armour Thyroid Compared to Synthetic T4 for the Treatment of Primary Hypothyroidism in Adult Participants
Recruiting
This study will evaluate the efficacy and safety of Armour Thyroid treatment compared with synthetic T4 in subjects who have primary hypothyroidism and are currently stabilized (i.e., in-range thyroid-stimulating hormone [TSH]) on synthetic T4 treatment. This study will also therefore evaluate the efficacy and safety of dose conversion from synthetic T4 therapy to Armour Thyroid therapy.
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
05/13/2024
Locations: Texas Diabetes and Endocrinology - Central Austin /ID# 255728, Austin, Texas
Conditions: Hypothyroidism
Dose-Finding Study Evaluating Effect on Body Composition of Enobosarm in Patients Taking a GLP-1 for Chronic Weight Mgmt
Recruiting
The primary objective of this study is to assess the effect of enobosarm on total lean mass as measured by DEXA in patients maintained on GLP-1 receptor agonists.
Gender:
All
Ages:
Between 60 years and 100 years
Trial Updated:
05/13/2024
Locations: Clinical Trials of Texas, LLC DBA Flourish Research, San Antonio, Texas
Conditions: Muscle Loss, Obesity
A Study to Test Different Doses of BI 1569912 in People With Depression Who Take Anti-depressive Medicine
Recruiting
This study is open to adults between 18 and 65 with a type of depression (major depressive disorder) for whom previous treatments for depression did not work. The purpose of the study is to find out whether a medicine called BI 1569912 helps people with depression. Participants continue their standard therapy throughout the study. Participants are put into 4 groups by chance. 3 of the 4 groups take different doses of BI 1569912. 1 group takes placebo. Placebo tablets looks like BI 1569912 but... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
05/13/2024
Locations: Grayline Research Center, Wichita Falls, Texas
Conditions: Depressive Disorder, Major
A Study of LY4101174 in Participants With Recurrent, Advanced or Metastatic Solid Tumors
Recruiting
The purpose of this study is to find out whether the study drug, LY4101174, is safe, tolerable and effective in participants with advanced, or metastatic solid tumors. The study is conducted in two parts - phase Ia (dose-escalation, dose-optimization) and phase Ib (dose-expansion). The study will last up to approximately 4 years.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Metastatic Solid Tumor, Recurrent Solid Tumor, Advanced Solid Tumor, Urinary Bladder Neoplasm, Triple Negative Breast Cancer, Non-small Cell Lung Cancer, Esophageal Cancer, Pancreatic Cancer, Ovarian Cancer, Cervical Cancer, Head and Neck Squamous Cell Carcinoma, Prostate Cancer, Renal Pelvis Cancer, Bladder Cancer
A Dose-ranging Study in Patients With Diabetic Peripheral Neuropathic Pain (DPNP)
Recruiting
Evaluation of the efficacy of LX9211 compared to placebo in reducing DPNP.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: Lexicon Investigational Site (193), Dallas, Texas
Conditions: Diabetic Peripheral Neuropathic Pain
A Study to Assess Safety and Efficacy of SOT201 in Patients With Advanced/Metastatic Cancer
Recruiting
This is a Phase 1, open-label, dose escalation study to assess the safety, tolerability, and preliminary efficacy of SOT201 as monotherapy for participants aged 18 years or above with advanced unresectable or metastatic solid tumors During dose escalation, the recommended dose(s) of SOT201 given every 3 weeks (Q3W) will be determined
Gender:
All
Ages:
18 years and above
Trial Updated:
05/13/2024
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Advanced Solid Tumor, Metastatic Solid Tumor
Exploring the Benefit of Peripheral Nerve Stimulation in Treating Pain From Chemo-induced Peripheral Neuropathy: A Longitudinal Single Center Feasibility Study
Recruiting
To learn if peripheral nerve stimulation (PNS) can help to improve pain in participants with CIPN.
Gender:
All
Ages:
Between 18 years and 85 years
Trial Updated:
05/13/2024
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Peripheral Nerve Stimulation, Chemotherapy-induced Peripheral Neuropathy