Texas is currently home to 5044 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Critical Care Results of SARS-CoV-2 ARDS by Dapsone and Standard COVID-19 Treatment
Recruiting
Abstract Background: Clinicians in pulmonary critical care medicine and critical care medicine considered dapsone administration to treat SARS-CoV-2 inflammasome. Dapsone is useful in the molecular regulation of Nod-like receptor family pyrin domain-containing 3 (NLRP3). Objective: To study the targeting of NLRP3 itself or up-/downstream factors of the NLRP3 inflammasome by dapsone must be responsible for its observed preventive effects, functioning as a competitor. Methods: Patients who were... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
06/07/2021
Locations: Hunt Regional Medical Center, Greenville, Texas
Conditions: SARS-CoV-2, Hypoxia, ARDS
Diet Patterns in IBD in Central Texas
Recruiting
The purpose of the study is to understand the diet patterns, preferences, and impact of diet on daily living in our patients with IBD in Central Texas.
Gender:
All
Ages:
18 years and above
Trial Updated:
05/18/2021
Locations: Dell Medical School, UT Austin, Austin, Texas
Conditions: Inflammatory Bowel Diseases, Crohn Disease, Ulcerative Colitis
Registry and Biorepository for IBD in Central Texas
Recruiting
This is a prospective, non-interventional registry and biorepository for patients with IBD. Longitudinal follow-up data is collected from both patients and their treating gastroenterologist during routine clinical encounters. The biorepository will consist of prospective collection of blood samples, tissue samples, and fecal samples for research purposes, while the participants are undergoing a clinically-indicated procedure (i.e. venipuncture for routine tests, IV catheter placement, and/or end... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
05/13/2021
Locations: Dell Medical School, UT Austin, Austin, Texas
Conditions: Crohn Disease, Ulcerative Colitis, Inflammatory Bowel Diseases
On Site Sensors Monitoring Impacts of Cognitive Decline on ADLs
Recruiting
The purpose of this research is to compare the effectiveness of a continuous monitoring system to assess Activities of Daily Living (ADLs) over time compared to the traditional assessments used by medical professionals as Alzheimer's Disease and Alzheimer's Disease Related Dementias (AD/ADRD) progresses.
Gender:
All
Ages:
65 years and above
Trial Updated:
04/29/2021
Locations: Birkeland Current, Waco, Texas
Conditions: Dementia, Dementia Alzheimers
Designing a Predictive Tool to Identify Whether a Cancer Patient Has Bacteremia Due to Ceftriaxone-Resistant Escherichia Coli
Recruiting
This study aims to develop a tool to predict whether a cancer patient has bacteria in the blood (bacteremia) due to ceftriaxone-resistant Escherichia (E.) coli. This study may help researchers identify risk factors for ceftriaxone-resistant E. coli bacteremia in cancer patients and improve antibiotic treatment in these patients.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/28/2021
Locations: M D Anderson Cancer Center, Houston, Texas
Conditions: Escherichia Coli Infection, Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm
Observational Study to Compare Outcomes of Different Psychiatric Treatment of Suicidal Adolescents
Recruiting
To address the unmet need of optimizing the treatment and management for adolescent suicidality, the investigators propose to evaluate the effectiveness and safety of telehealth services compared to inpatient and OCIC for suicidal adolescents in target population. To achieve this goal, the investigators propose a multi- site study to compare telehealth, OCIC, and inpatient care, and see which can lead to a lower risk of a suicidal event (primary outcome) as well as higher treatment satisfaction... Read More
Gender:
All
Ages:
Between 12 years and 18 years
Trial Updated:
04/26/2021
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Suicidal Ideation
Prospective Evaluation of Chronic Pancreatitis for Epidemiologic and Translational Studies, the PROCEED Study
Recruiting
This study gathers information on patients at different stages of chronic pancreatitis to better understand the natural course and risk factors associated with pancreatitis. Chronic pancreatitis is a disease that occurs when the pancreas is inflamed (swollen and irritated) all of the time. It is important for doctors to diagnose chronic pancreatitis in the beginning stages of the disease. Over time, as chronic pancreatitis gets worse, the pancreas may stop working correctly. Since treatment opti... Read More
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
04/22/2021
Locations: Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center, Houston, Texas
Conditions: Acute Pancreatitis, Chronic Pancreatitis
To Assess the Safety, Tolerability and Efficacy of Itacitinib Immediate Release Tablets in Participants With Primary or Secondary Myelofibrosis Who Have Received Prior Ruxolitinib and/or Fedratinib Monotherapy. (LIMBER-213)
Recruiting
This is a 2-part study. In Part 1, participants will be dosed at 2 different dose levels in order to select the RP2D for Part 2 of the study.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/27/2021
Locations: Renovatio Clinical Consultants Llc, Spring, Texas
Conditions: Myelofibrosis, Polycythemia Vera, Thrombocythemia
To Evaluate the Efficacy and Safety of Parsaclisib and Ruxolitinib in Participants With Myelofibrosis (LIMBER-313)
Recruiting
The purpose of the study is to compare the efficacy of parsaclisib when combined with ruxolitinb versus placebo combined with ruxolitinib in participants with myelofibrosis.
Gender:
All
Ages:
18 years and above
Trial Updated:
03/24/2021
Locations: Renovatio Clinical, Houston, Texas
Conditions: Myelofibrosis, Primary Myelofibrosis, Post Essential Thrombocythemia Myelofibrosis, Post Polycythemia Vera Myelofibrosis
Panoptix Trifocal Lens in Post Refractive Myopic Laser Vision Correction Surgery
Recruiting
The two main objectives of this study are to demonstrate safety and effectiveness of implanting the PanOptix Trifocal IOL in patients who have had previous myopic Lasik. The primary objectives to demonstrate clinical safety will be the quality of vision questionnaire (QUVID) which will demonstrate the patient's perception of halos, glares, and starbursts before and after the implantation of the trifocal IOL. The primary objective to demonstrate clinical effectiveness will be done by measuring v... Read More
Gender:
All
Ages:
22 years and above
Trial Updated:
03/15/2021
Locations: Parkhurst NuVision, San Antonio, Texas
Conditions: Cataract, Refractive Errors
Pullback Pressure Gradient (PPG) Global Registry
Recruiting
The purpose of this study is to determine the predictive capacity of the Pullback Pressure Gradient (PPG) index for post-PCI FFR and to determine the impact of the PPG index on clinical decision making about revascularization and on clinical outcomes.
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
03/04/2021
Locations: Memorial Hermann Texas Medical Center, Texas City, Texas
Conditions: Chronic Coronary Insufficiency, Non ST Elevation Myocardial Infarction
Veteran Affairs Osteoarthritis Knee Study
Recruiting
A clinical study at the Dallas Veterans Affairs, is being proposed to test the efficacy of a novel electrical stimulation platform named the Pro-Sport Ultra® device by AVAZZIA to reduce pain and increase activity level in patients with knee osteoarthritis.
Gender:
All
Ages:
Between 18 years and 70 years
Trial Updated:
03/04/2021
Locations: Veteran Affairs North Texas Healthcare System, Dallas, Texas
Conditions: Knee Osteoarthritis