Texas is currently home to 5071 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Houston, Dallas, San Antonio and Austin. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Study of MPT-0118 in Subjects With Advanced or Metastatic Refractory Solid Tumors
NCT04859777
Recruiting
This is a Phase 1/1b open-label, dose-escalation, and cohort expansion study with BID (tablet) oral dose of MPT-0118 in subjects with advanced or metastatic refractory solid tumors. The study will be conducted in 3 parts: Part A: MPT-0118 dose-escalation Part B: MPT-0118 dose-escalation in combination with pembrolizumab Part C: Cohort expansion of MPT-0118 in combination with pembrolizumab
Gender:
All
Ages:
18 years and above
Trial Updated:
09/15/2021
Locations: MD Anderson Cancer Center, Houston, Texas
Conditions: Solid Tumor, Adult, Advanced Solid Tumor, Advanced Cancer, Metastatic Cancer, Refractory Cancer
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Impact of a Mobile App on Pregnant Women's Prenatal Genetic Testing Decision-making
NCT05055700
Recruiting
Determine the effect of a culturally sensitive prenatal genetic testing (PGT) education intervention delivered via a mobile application on pregnant women's perceptions, knowledge, and uptake of PGT. Our working hypothesis, based on prior studies, is that pregnant women who receive a culturally sensitive intervention to enhance their knowledge and understanding of PGT will feel more confident in their decision-making regarding PGT.
Gender:
Female
Ages:
18 years and above
Trial Updated:
09/14/2021
Locations: Driscoll Children's hospital, Corpus Christi, Texas
Conditions: Pregnant Women, Mobile Applications, Genetic Testing, Prenatal Care
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Myeloma-Developing Regimens Using Genomics (MyDRUG)
NCT03732703
Recruiting
The MyDRUG study is a type of Precision Medicine trial to treat patients with drugs targeted to affect specific genes that are mutated as part of the disease. Mutations in genes can lead to uncontrolled cell growth and cancer. Patients with a greater than 25% mutation to any of the following genes; CDKN2C, FGFR3, KRAS, NRAS, BRAF V600E, IDH2 or T(11;14) can be enrolled to one of the treatment arms. These arms have treatments specifically directed to the mutated genes. Patients that do not have a... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
09/09/2021
Locations: UT Southwestern Medical Center, Dallas, Texas
Conditions: Relapsed Refractory Multiple Myeloma
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A Randomized Control Trial of a Responsive Parenting Intervention to Support Healthy Brain Development and Self-regulation in Toddlers Born Preterm
NCT04856501
Recruiting
The purpose of this study is to determine whether participation in the Play and Learning Strategies (PALS) parenting intervention results in increased caregiver responsiveness behaviors and to test if participation in PALS results in increases in toddler skills and/or toddler neurological development.
Gender:
All
Ages:
Between 15 months and 30 months
Trial Updated:
09/03/2021
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Premature Birth
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GARNET™ Filter (GARNET Device) IDE Used in Chronic Hemodialysis Patients With a Bloodstream Infection
NCT04658017
Recruiting
To evaluate the feasibility of performing combined hemodialysis with the GARNET device in chronic hemodialysis patients with a blood stream infection (BSI), and measure clinical performance and safety endpoints.
Gender:
All
Ages:
Between 18 years and 90 years
Trial Updated:
09/01/2021
Locations: Houston Methodist, Houston, Texas
Conditions: Bloodstream Infection
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iGlucose® Remote Patient Monitoring Device as an Adjunct to Routine Glucose Meter Devices for Glycemic Management and Control in Gestational Diabetes
NCT04206748
Recruiting
The purpose of this study is to investigate whether automation of glucose monitoring data to facilitate the total number of recommended and completed SMBG checks improve clinical outcomes for women living with gestational and type 2 diabetes during pregnancy? This is a RCT
Gender:
Female
Ages:
18 years and above
Trial Updated:
09/01/2021
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Gestational Diabetes, Type2 Diabetes, Pregnancy in Diabetic
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Verticalization Robotic Exoskeleton DoC
NCT04833543
Recruiting
Mobilization, specifically verticalization, has been shown to play a role in enhancing consciousness. Vestibular stimulation has the potential to influence the neural substrate of consciousness, but this modality has not been thoroughly explored. The primary aim of this study is to compare the influence of verticalization with and without vestibular input on level of consciousness in patients experiencing disorders of consciousness (DoC).
Gender:
All
Ages:
Between 18 years and 75 years
Trial Updated:
08/31/2021
Locations: TIRR Memorial Hermann, Houston, Texas
Conditions: Brain Injuries, Disorder of Consciousness
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Genetic Mechanism of Conserved Ancestral Haplotype in SCA10
NCT04495426
Recruiting
Spinocerebellar ataxia type 10 (SCA10) is a hereditary ataxia whose ancestral mutation occurred in East Asia. The mutation is likely to have migrated during peopling of American continents from East Asia. We found a specific rare DNA variation associated with SCA10. We test whether this variation played a key role in the birth and subsequent spreading of SCA10 mutation.
Gender:
All
Ages:
18 years and above
Trial Updated:
08/30/2021
Locations: Houston Methodist Hospital, Houston, Texas
Conditions: Spinocerebellar Ataxia Type 10
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The Impact of Social Phone Calls With Isolated Older Adults Receiving Protective Services for Abuse, Neglect and/or Exploitation
NCT05026762
Recruiting
The purpose of this study is to see the the impact of social visits, through weekly phones calls, on quality of life outcomes of depression, anxiety, loneliness, isolation and self-rated health for older adults visited by Adult Protective Services (APS) for abuse, neglect and/or exploitation (ANE) and to also to determine the benefit of these conversations on the medical student's perspective of aging and ANE.
Gender:
All
Ages:
65 years and above
Trial Updated:
08/24/2021
Locations: The University of Texas Health Science Center at Houston, Houston, Texas
Conditions: Senior Abuse
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The EndRAD Trial: Eliminating Total Body Irradiation (TBI) for NGS-MRD Negative Children, Adolescents, and Young Adults With B-ALL
NCT03509961
Recruiting
This study will evaluate the use of non- TBI (total body irradiation) conditioning for B-ALL patients with low risk of relapse as defined by absence of NGS-MRD (next generation sequencing minimal residual disease) before receiving a hematopoietic cell transplant (HCT). Patients diagnosed with B-ALL who are candidates for HCT will be screened by NGS-MRD on a test of bone marrow done before the HCT. Subjects who are pre-HCT NGS-MRD negative will be eligible to receive a non-TBI conditioning regime... Read More
Gender:
All
Ages:
Between 1 year and 25 years
Trial Updated:
08/20/2021
Locations: The University of Texas M. D. Anderson Cancer Center, Houston, Texas
Conditions: B-cell Acute Lymphoblastic Leukemia
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Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery
NCT04997291
Recruiting
Cardiopulmonary bypass and arrest of the heart during cardiac surgery are necessary to allow the surgeon to perform heart operations. However, these processes can cause injury to the heart which may worsen post-operative outcomes. In fact, the effects of these injuries may continue after surgery, and lead to a long-term decrease in heart function. Neonates and young infants are at particular risk for this occurrence. While much research has been done in adults looking for medicines that might p... Read More
Gender:
All
Ages:
1 year and below
Trial Updated:
08/02/2021
Locations: Dell Children's Medical Center of Central Texas, Austin, Texas
Conditions: Heart Defects, Congenital
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Safety, Tolerability, PK, and Analgesic Effect of INL-001 in Children Following Open Inguinal Hernia Repair
NCT03262688
Recruiting
A multicenter, single-dose study in children 12 to <17 years of age, 6 to <12 years of age, and 2 to <6 years of age who are scheduled for elective open inguinal hernia repair. Enrollment in this study will start with the oldest age group (12 to <17 years) and will continue in a stepwise fashion until appropriate doses are established for all 3 pediatric age groups (12 to <17 years, 6 to <12 years, 2 to <6 years).
Gender:
All
Ages:
Between 2 years and 16 years
Trial Updated:
07/23/2021
Locations: Driscoll Children's Hospital, Corpus Christi, Texas
Conditions: Inguinal Hernia, Postoperative Pain
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