Ohio is currently home to 3199 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Cincinnati, Columbus, Cleveland and Dayton. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
A Safety and Pharmacokinetics Study of IDP-118 Lotion in Pediatric Participants With Plaque Psoriasis
NCT03988439
Recruiting
This study is to evaluate the safety, the systemic exposure, and the hypothalamic-pituitary-adrenal (HPA) axis suppression potential for topically applied IDP-118 lotion in pediatric participants with moderate to severe plaque psoriasis.
Gender:
ALL
Ages:
Between 4 years and 17 years
Trial Updated:
07/25/2023
Locations: Bausch Site 11, Mayfield Heights, Ohio
Conditions: Psoriasis
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Design Validation Hemodynamic Study of New Kendall SCD SmartFlow Compression System
NCT05945186
Recruiting
This study is being conducted to evaluate the hemodynamic performance (i.e. flow of blood) in the legs using the new Kendall SCD SmartFlow™ compression system with Cardinal Health Element compression sleeves.
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
07/13/2023
Locations: Jobst Vascular Institute, Toledo, Ohio
Conditions: Hemodynamics
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CPAP Adherence Pilot Study Among African Americans
NCT05955287
Recruiting
The goal of the study is to determine the feasibility of a behavioral intervention to improve CPAP adherence among African American patients with obstructive sleep apnea.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/12/2023
Locations: MetroHealth Medical System, Cleveland, Ohio
Conditions: Sleep Apnea
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An All Comers Registry For Normothermic Ex Vivo Lung Perfusion (EVLP) as Assessment of Donor Lungs for Transplant
NCT05101460
Recruiting
The XVIVO Registry is to collect standard of care clinical data from "all-comers" who are transplanted with an EVLP lung treated with the XVIVO Perfusion System™ in order to assess the long-term performance of the device, and monitor device-related serious adverse events. In addition, 4 and 5-year UNOS registry data of the 126 subjects who received an EVLP transplant under the NOVEL and NOVEL Extension studies are provided as part of the long-term safety and quality of life data. In addition, 4... Read More
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/11/2023
Locations: Cleveland Clinic Foundation, Cleveland, Ohio
Conditions: Lung Transplant
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Ketamine-Assisted Mindfulness-Based Cognitive Therapy for Depression: A Pilot Study
NCT05950711
Recruiting
The purpose of this study is to assess the feasibility of combining IV ketamine, a rapid acting antidepressant, with a course of Mindfulness-Based Cognitive Therapy (MBCT), for the initial and maintenance treatment of depression.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/10/2023
Locations: Harding Hospital, Columbus, Ohio
Conditions: Major Depressive Disorder
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Magnetocardiography as a Noninvasive Diagnostic Strategy for Identifying Coronary Allograft Vasculopathy
NCT05751915
Recruiting
Purpose: To show early feasibility of magnetocardiography (MCG) to identify coronary Cardiac positron emission tomography (PET) is the preferred non-invasive tests to assess for CAV and incorporation of quantitative myocardial blood flow (MBF) assessment improves diagnostic accuracy. Based on ISHLT criteria, the following have been proposed for diagnosis of CAV by PET:
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/10/2023
Locations: The Cleveland Clinic, Cleveland, Ohio
Conditions: Coronary Allograft Vasculopathy (CAV)
Register for Updates
Simple Bone Cysts in Kids
NCT02193841
Recruiting
Simple bone cysts (SBCs) are cysts filled with fluid that occur most frequently in the long bones (arms or legs) of children. There are many ways to treat SBCs but it is unclear if one is better than another. The purpose of this research trial is to compare the effectiveness of two common treatments that are used by surgeons today.
Gender:
ALL
Ages:
Between 2 years and 21 years
Trial Updated:
07/10/2023
Locations: Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio
Conditions: Bone Cyst
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Strategies to Augment Ketosis: Ketone Conferred Resiliency Against Sleep Restriction
NCT05519644
Recruiting
Sleep deprivation is a major problem in military populations. Some major consequences of sleep loss are inability to concentrate, poor work efficiency, and increase in errors during daily tasks. There is some evidence that ketone ester supplements may lessen the adverse effects of sleep restriction. The main purpose of these supplements is to raise your blood concentration of ketones, which are safe, small molecules that appear in the blood during fasting, when following a ketogenic diet, or con... Read More
Gender:
ALL
Ages:
Between 18 years and 40 years
Trial Updated:
07/06/2023
Locations: The Ohio State University, Columbus, Ohio
Conditions: Sleep Deprivation
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Feto-Endoscopic Tracheal Occlusion (FETO) for Left Congenital Diaphragmatic Hernia
NCT02986087
Recruiting
Tracheal occlusion IDE approved by FDA for congenital diaphragmatic hernia fetuses.
Gender:
FEMALE
Ages:
Between 18 years and 50 years
Trial Updated:
07/05/2023
Locations: Cincinnati Children's Hospital Medical Center (CCHMC), Cincinnati, Ohio
Conditions: Congenital Diaphragmatic Hernia, Pulmonary Hypoplasia, Pulmonary; Hypertension
Register for Updates
IMPACT - AndHealth Autoimmune Research Registry
NCT05883371
Recruiting
This is a patient research registry aimed at evaluating the effectiveness of a comprehensive, root-cause medical approach ("AndHealth program") for autoimmune disorders. This approach involves a combination of pharmacological and non-pharmacological therapies offered under the care of a licensed physician with the support of health coaches. While protocol guidance is provided, the therapeutic approach is personalized to the individual needs of patients. The autoimmune disorders of focus in this... Read More
Gender:
ALL
Ages:
Between 18 years and 70 years
Trial Updated:
06/28/2023
Locations: AndHealth, Columbus, Ohio
Conditions: Arthritis, Rheumatoid, Arthritis, Psoriatic, Psoriasis, Ankylosing Spondylitis, Autoimmune Diseases
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Developing E-liquid Product Standards (Sweet Spot Study)
NCT05864586
Recruiting
The Sweet Spot Study aims to evaluate the effect of e-liquids with nicotine varying in freebase (FB) levels and concentrations on the appeal of electronic cigarettes (ECs) in young adult EC users with minimal/no history of smoking and older adult smokers.
Gender:
ALL
Ages:
Between 21 years and 50 years
Trial Updated:
06/20/2023
Locations: Ohio State University Comprehensive Cancer Center, Columbus, Ohio
Conditions: Nicotine, Nicotine Vaping, E-cigarette Use
Register for Updates
BESTMED: Observational Evaluation of Second Line Therapy Medications in Diabetes
NCT05161429
Recruiting
An observational study of electronic patient data to compare diabetes medications and to determine which ones offer the best balance of risks and benefits.
Gender:
ALL
Ages:
30 years and above
Trial Updated:
06/16/2023
Locations: Greater Plains Collaborative, Beachwood, Ohio
Conditions: Diabetes Mellitus, Type 2
Register for Updates