Alabama is currently home to 1229 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Birmingham, Mobile, Huntsville and Anniston. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Muscle Recovery After Critical Illness
NCT05537298
Recruiting
The overarching goal of the proposed study is to determine the trajectories of physical recovery and cellular markers involved with the underlying failure to recover muscle after critical illness, while exploring which characteristics are associated with sustained physical disability. This proposal will examine muscle pathophysiology carefully aligned with physical function outcomes in order to longitudinally assess the recovery, or failed recovery, of muscle function in participants after criti... Read More
Gender:
MALE
Ages:
18 years and above
Trial Updated:
06/11/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: ICU Acquired Weakness, Post Intensive Care Unit Syndrome, Muscle Weakness, Critical Illness
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Impact of Astaxanthin on Cognition in Recreationally Active Females
NCT06460181
Recruiting
The purpose of this study is to examine the protentional that the antioxidant Astaxanthin has on mitigating cognitive decline following mental fatigue.
Gender:
FEMALE
Ages:
Between 18 years and 39 years
Trial Updated:
06/10/2024
Locations: University of North Alabama, Florence, Alabama
Conditions: Mental Fatigue
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Effects of Spencer's Technique on Shoulder Function
NCT06447493
Recruiting
The purpose of this study is to see the impact of a modified Spencer's technique on tissue stiffness, mobility, and blood flow of the shoulder joint. Spencer's technique is a well-known osteopathic manipulative treatment (OMT) that is common for treating adhesive capsulitis and is believed to help blood flow. There are studies that look at the clinical effects of the technique and/or compare it to other techniques; however, measuring the extent to which Spencer's technique, or this modified tech... Read More
Gender:
ALL
Ages:
Between 18 years and 50 years
Trial Updated:
06/10/2024
Locations: Edward Via College of Osteopathic Medicine-Auburn, Auburn, Alabama
Conditions: Shoulder
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Intensive Glycemic Targets in Overweight and Obese Women With Gestational Diabetes
NCT05124808
Recruiting
This is a multicenter randomized clinical trial of 828 overweight and obese individuals with gestational diabetes designed to compare standard to intensive glycemic targets.
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
06/09/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Gestational Diabetes, Pregnancy, High Risk, Overweight and Obesity
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Glaucoma, Visual Field Loss, and Their Association With Life Space in Older Adults
NCT04396002
Recruiting
Mobility refers to a person's purposeful movement through the environment from one place to another and can be conceptualized as a continuum from bed bound (immobility) on one extreme to making excursions to distant locations on the other extreme. Primary open-angle glaucoma (POAG) is a chronic, progressive optic neuropathy that can lead to gradual loss of vision in the peripheral field and central vision. Older adults with POAG have an increased risk for motor vehicle collisions and falls. More... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
06/06/2024
Locations: University of Alabama Birmingham, Birmingham, Alabama
Conditions: Primary Open Angle Glaucoma
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Roflumilast or Azithromycin to Prevent COPD Exacerbations (RELIANCE)
NCT04069312
Recruiting
A multi-center, randomized, 72-month, parallel- group, non-inferiority, phase III study to compare the effectiveness of roflumilast (Daliresp, 500 mcg quaque die (QD) or alternate regimen) therapy versus azithromycin (250 mg QD, 500 mg QD three times per week, or alternate regimen) to prevent hospitalization or death in a patients at high risk for COPD exacerbations.
Gender:
ALL
Ages:
40 years and above
Trial Updated:
06/06/2024
Locations: University of Alabama, Birmingham, Alabama
Conditions: Chronic Obstructive Pulmonary Disease Severe, Chronic Bronchitis
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Kidney Transplantation From Donors With HIV: Impact on Rejection and Long-Term Outcomes (Expanding HOPE Kidney)
NCT06263426
Recruiting
This research is being done to better understand rejection in transplant recipients with HIV who receive kidneys from donors with vs without HIV.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
06/05/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Hiv
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A Study to Evaluate the Safety and Efficacy of Baricitinib in the Treatment of Frontal Fibrosing Alopecia (FFA)
NCT06240351
Recruiting
The goal of this clinical trial is to evaluate the safety and efficacy of Baricitinib in the treatment of frontal fibrosing alopecia (FFA).
Gender:
FEMALE
Ages:
Between 18 years and 90 years
Trial Updated:
06/03/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Frontal Fibrosing Alopecia
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Histiocytic Disorder Follow-up Study
NCT05915208
Recruiting
The purpose of the study is to describe the burden of chronic health conditions, psychological dysfunction, chronic pain, healthcare utilization, worse health-related quality of life, overall mortality, and cause-specific mortality among individuals with histiocytic disorders
Gender:
ALL
Ages:
Between 0 years and 89 years
Trial Updated:
06/03/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Histiocytosis, Langerhans Cell Histiocytosis, Erdheim-Chester Disease, Rosai Dorfman Disease, Xanthogranuloma, Malignant Histiocytoses
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Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic Lymphohistiocytosis
NCT05898477
Recruiting
The purpose of the study is to describe Hemophagocytic lymphohistiocytosis (HLH) in patients with lymphoma to identify possible therapeutic strategies to improve overall survival of the patients with lymphoma associated hemophagocytic lymphohistiocytosis.
Gender:
ALL
Ages:
All
Trial Updated:
06/03/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Lymphoma, Hemophagocytic Lymphohistiocytoses
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Eliminating Monitor Overuse Trial (EMO Trial)
NCT05132322
Recruiting
The purpose of this study is to identify the optimal deimplementation strategies for an overused practice: continuous pulse oximetry monitoring of children hospitalized with bronchiolitis who are not receiving supplemental oxygen.
Gender:
ALL
Ages:
2 months and above
Trial Updated:
06/03/2024
Locations: Children's of Alabama, Birmingham, Alabama
Conditions: Bronchiolitis Acute Viral
Register for Updates
Shaping the Indications for Periodontal Adjunctive Antibiotics in Dental Practice
NCT06131021
Recruiting
Periodontitis is a bacterial inflammatory disease and antibiotic use is being empirically used as part of its treatment. However, a clinical practice guideline on periodontal treatment adjuncts published in 2015 identified weak evidence on the use of systemic antibiotics and large heterogeneity across small scale studies, suggesting that larger pragmatic clinical trials would benefit clinical decision making. This will be a prospective, randomized, placebo-controlled trial, stratified by practic... Read More
Gender:
ALL
Ages:
40 years and above
Trial Updated:
05/30/2024
Locations: University of Alabame, Birmingham, Alabama
Conditions: Periodontitis, Periodontal Diseases, Periodontal Pocket
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