Alabama is currently home to 1297 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Birmingham, Mobile, Huntsville and Anniston. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Pilot of Reconnecting to Internal Sensations and Experiences in Undergraduates
NCT05285111
Recruiting
Project RISE is a randomized control trial. The intervention consists of four modules that focus on multiple aspects of interoception including: body awareness, body sensations/movement, eating, health and self-care, emotional awareness, and understanding the self in relation to others. The comparator condition is called "Health Habits" and is matched for time and attention; participants complete modules related to healthy habits such as financial planning, hygiene, stretching, and healthy eatin... Read More
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
07/18/2023
Locations: Auburn University, Auburn, Alabama
Conditions: Suicidal Ideation, Eating Disorder Symptom
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Predicton of Sepsis Recovery Performance Subtypes Pilot Study
NCT05912413
Recruiting
This study addresses critically ill sepsis patients' current literature reports of ongoing post-hospital discharge weakness and hospital readmissions. This study is aimed at capture and interpretation of a complex set of tests, administered during a subject's sepsis functional recovery trajectory, particularly capturing hospital readmission's effects on survivors' physical function recovery.
Gender:
All
Ages:
Between 18 years and 80 years
Trial Updated:
07/11/2023
Locations: University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama
Conditions: Sepsis
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Prehabilitation Feasibility Among Older Adults Undergoing Transplantation
NCT05642884
Recruiting
This is a pilot feasibility trial among older adults (≥60y) scheduled to undergo Autologous Stem Cell transplantation at UAB. Participants will be randomized into either a prehabilitation program or an attention control group before their transplant. The primary outcomes will be feasibility and secondary outcomes include changes in physical function at the time of transplant and at 12 weeks follow up.
Gender:
All
Ages:
60 years and above
Trial Updated:
07/11/2023
Locations: Kirklin Clinic of UAB Hospital, Birmingham, Alabama
Conditions: Multiple Myeloma
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Non-Invasive Monitoring of Traumatic Brain Injury Progression Using the Infrascanner (MOBI-1)
NCT04893837
Recruiting
MOBI-1 is a multicenter clinical trial that will evaluate the use of the Infrascanner for the monitoring of traumatic intracranial hematomas.
Gender:
All
Ages:
15 years and above
Trial Updated:
07/11/2023
Locations: UAB Hospital, Birmingham, Alabama
Conditions: Brain Injuries, Traumatic
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Simple Bone Cysts in Kids
NCT02193841
Recruiting
Simple bone cysts (SBCs) are cysts filled with fluid that occur most frequently in the long bones (arms or legs) of children. There are many ways to treat SBCs but it is unclear if one is better than another. The purpose of this research trial is to compare the effectiveness of two common treatments that are used by surgeons today.
Gender:
All
Ages:
Between 2 years and 21 years
Trial Updated:
07/10/2023
Locations: Children's Hospital of Alabama, Birmingham, Alabama
Conditions: Bone Cyst
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Platelet Rich Plasma as an Adjunct Therapy at the Time of Transvaginal Native Tissue Prolapse Surgery
NCT05731284
Recruiting
The purpose of the study is to evaluate the surgical outcomes of injecting platelet-rich plasma (PRP) into the vaginal tissue as an adjunct therapy at the time of prolapse surgery
Gender:
Female
Ages:
18 years and above
Trial Updated:
07/06/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Pelvic Organ Prolapse
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Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Patients With Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer
NCT03971409
Recruiting
This phase II trial studies how well the combination of avelumab with liposomal doxorubicin with or without binimetinib, or the combination of avelumab with sacituzumab govitecan works in treating patients with triple negative breast cancer that is stage IV or is not able to be removed by surgery (unresectable) and has come back (recurrent). Immunotherapy with checkpoint inhibitors like avelumab require activation of the patient's immune system. This trial includes a two week induction or lead-... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
07/06/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Stage III Breast Cancer, Stage IIIA Breast Cancer, Stage IIIB Breast Cancer, Stage IIIC Breast Cancer, Stage IV Breast Cancer, Invasive Breast Carcinoma, Recurrent Breast Carcinoma, Triple-Negative Breast Carcinoma, Unresectable Breast Carcinoma
Register for Updates
UAB Alzheimer's Disease Center Core Cohort - Tau Imaging Substudy
NCT03809351
Recruiting
The primary objective of this study is to measure the concentration and the regional brain distribution of pathologic tau deposition using the PET tracer AV-1451 in participants in the UAB-ADC cohort. The amount and distribution of AV-1451 in the brain will be correlated to demographic, clinical, genetic, and biospecimen data acquired through the separate ongoing UAB-ADC study. Assessment of interactions between race and vascular risk factors, brain tau levels measured with AV-1451-PET, and cogn... Read More
Gender:
All
Ages:
50 years and above
Trial Updated:
07/06/2023
Locations: UAB, Birmingham, Alabama
Conditions: Alzheimer Disease
Register for Updates
Pilot-testing the Effect of Magnetic Mitohormesis Therapy for Treating Frailty in Older Adults
NCT05930470
Recruiting
Thirty (30) adults with limited physical function will be recruited to participate in a double-blind pilot randomized controlled crossover trial in which all participants will receive 12-weeks of twice weekly MMT treatment in the first (Phase 1) or second half (Phase 2) of the study period; during the control period, participants will receive sham treatment and will be blinded to the randomization.
Gender:
All
Ages:
60 years and above
Trial Updated:
07/03/2023
Locations: Auburn University, Auburn, Alabama
Conditions: Frailty
Register for Updates
Determining the Role of Social Reward Learning in Social Anhedonia
NCT05617898
Recruiting
This is a clinical trial study that aims to evaluate the specificity of the relationship between reduced sensitivity to social reward and social anhedonia at both behavioral and neural levels. Individuals who recently experienced their first-episode psychosis will be recruited. Participants will be randomized 1:1 to motivational interviewing or a time- and format-matched control probe. At pre- and post-probe, participants will perform two social reward learning tasks in the scanner. With this de... Read More
Gender:
All
Ages:
Between 18 years and 35 years
Trial Updated:
07/03/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Psychosis
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Functional Consequences of T-bet Expression in Flu-specific Memory B Cells After Live Attenuated Influenza Vaccine (LAIV)
NCT04080245
Recruiting
As yet the investigators do not understand if there are biomarkers of immune protection after the Flumist or Live Attenuated Flu Vaccine (LAIV). Here the investigators test the hypothesis that the T-bet expressing fraction of flu-specific B cells after live attenuated influenza vaccination also serves as an early biomarker of long-lived antibody responses after vaccination. In this study the investigators will be providing the LAIV to up to 10 healthy subjects and assaying their immune response... Read More
Gender:
All
Ages:
Between 18 years and 50 years
Trial Updated:
07/03/2023
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Influenza, Human
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Interventions to Decrease Financial Toxicity
NCT05939440
Recruiting
Financial distress affects 30-70% of cancer patients and describes the burden that patients experience due to the costs of care (CoC). One reason may be because patients lack the appropriate information on CoC that would help them better plan for and manage their CoC. Therefore, the investigators plan to test a Proactive CoC intervention which includes a discussion with a trained educator on CoC information and a Cost Tracking tool to help patients deal with their CoC.
Gender:
Female
Ages:
18 years and above
Trial Updated:
06/30/2023
Locations: O'Neal Comprehensive Cancer Center, Birmingham, Alabama
Conditions: Cancer, Breast, Cancer Colorectal, Cancer, Ovarian, Cervical Cancer, Uterine Cancer, Vulvar Cancer
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