Alabama is currently home to 1237 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Birmingham, Mobile, Huntsville and Anniston. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Mindfulness Intervention for College Students With ADHD
NCT06076967
Recruiting
Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder that commonly persists into adulthood and is associated with significant life impairments. The current study evaluates the feasibility, acceptability, and preliminary efficacy of a group-based mindfulness intervention for first-year college students with ADHD. If found to be feasible, acceptable, and efficacious, subsequent research will examine its impact on a larger scale to have a broader public health impact for... Read More
Gender:
ALL
Ages:
Between 17 years and 25 years
Trial Updated:
08/09/2024
Locations: Department of Psychology, University of Alabama, Tuscaloosa, Alabama
Conditions: Attention Deficit Hyperactivity Disorder
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Study to Evaluate Biological & Clinical Effects of Significantly Corrected CFTR Function in Infants & Young Children
NCT04509050
Recruiting
This is a two-part, multi-center, prospective longitudinal, exploratory study of highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators and their impact on children with cystic fibrosis (CF).
Gender:
ALL
Ages:
10 years and below
Trial Updated:
08/08/2024
Locations: The Children's Hospital Alabama, University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cystic Fibrosis
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ABTECT - Maintenance
NCT05535946
Recruiting
This is a multicenter, randomized, placebo-controlled study to evaluate the long-term efficacy and safety of ABX464 50mg and 25mg administered once daily (QD) as maintenance therapy in subjects with moderately to severely active ulcerative colitis who have inadequate response, no response, a loss of response, or an intolerance to either conventional therapies \[corticosteroids, immunosuppressant (i.e. azathioprine, 6-mercaptopurine, methotrexate)\] and/or advanced therapies \[biologics (TNF inhi... Read More
Gender:
ALL
Ages:
16 years and above
Trial Updated:
08/06/2024
Locations: University of Alabama -Birmingham, Birmingham, Alabama
Conditions: Ulcerative Colitis
Register for Updates
A Person-Centered Geotagged Social Networking System to Promote Physical Activity in the Community
NCT05216393
Recruiting
The multilevel socio-ecological barriers to physical activity experienced by people with physical disabilities cut across structures and systems, community, institutions and organizations, interpersonal, and individual levels. Several studies have attempted to understand these barriers and facilitators, but to date, no study or system has attempted to systematically resolve these multilevel barriers and capitalize on the potential facilitators that can increase access to exercise and recreation... Read More
Gender:
ALL
Ages:
Between 18 years and 64 years
Trial Updated:
08/05/2024
Locations: UAB / Lakeshore Research Collaborative, Birmingham, Alabama
Conditions: Physical Inactivity, Disability Physical
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NTX-301 in MDS/AML
NCT04167917
Recruiting
NTX-301 is a DNMT1 inhibitor. The drug is an oral drug with preclinical data that has shown preclinical anti-leukemic efficacy. This is the first clinical trial using NTX-301 in patients with myeloid malignancies.
Gender:
MALE
Ages:
18 years and above
Trial Updated:
08/05/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Acute Myeloid Leukemia, Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia
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Predicton of Sepsis Recovery Performance Subtypes Pilot Study
NCT05912413
Recruiting
This study addresses critically ill sepsis patients' current literature reports of ongoing post-hospital discharge weakness and hospital readmissions. This study is aimed at capture and interpretation of a complex set of tests, administered during a subject's sepsis functional recovery trajectory, particularly capturing hospital readmission's effects on survivors' physical function recovery.
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
07/29/2024
Locations: University of Alabama at Birmingham (UAB) Hospital, Birmingham, Alabama
Conditions: Sepsis
Register for Updates
Pilot of Reconnecting to Internal Sensations and Experiences in Undergraduates
NCT05285111
Recruiting
Project RISE is a randomized control trial. The intervention consists of four modules that focus on multiple aspects of interoception including: body awareness, body sensations/movement, eating, health and self-care, emotional awareness, and understanding the self in relation to others. The comparator condition is called "Health Habits" and is matched for time and attention; participants complete modules related to healthy habits such as financial planning, hygiene, stretching, and healthy eatin... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
07/29/2024
Locations: Auburn University, Auburn, Alabama
Conditions: Suicidal Ideation, Eating Disorder Symptom
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MYLUNG Consortium Part 3: Observational Study
NCT05885698
Recruiting
This longitudinal study looks to quantify the testing timeline, operational barriers, and outcomes of biomarker-guided therapy in a large, community-based, and largely unselected patient population with early stage and advanced stage, treatment-naive non-small cell lung cancer, whether squamous or non-squamous.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/17/2024
Locations: Southern Cancer Center, PC, Daphne, Alabama
Conditions: Carcinoma, Non-Small-Cell Lung
Register for Updates
Phase 2 Safety and Efficacy Evaluation of AL8326 in ≥2nd Line SCLC
NCT05363280
Recruiting
This trial is a Phase II trial designed to evaluate the safety and efficacy of using oral AL8326 , a multi-targeted receptor Tyrosine Kinase Inhibitor( TKI) , to recurrent, advanced, or metastatic small cell lung cancer (SCLC) patients who need ≥2nd line treatment .
Gender:
ALL
Ages:
18 years and above
Trial Updated:
07/12/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Small Cell Lung Cancer
Register for Updates
Early Intervention to Promote Cardiovascular Health of Mothers and Children
NCT06272045
Recruiting
Early Intervention to Promote Cardiovascular Health of Mothers and Children (ENRICH) is a cluster randomized clinical trial, funded by the National Heart Lung \& Blood Institute. The study is designed to test the effectiveness of home visiting intervention to promote cardiovascular health and reduce disparities in maternal and early childhood cardiovascular health. Sites, in partnership with evidence-based home visiting programs, are recruiting 6400 participants in total (i.e., 3200 parent-dyads... Read More
Gender:
FEMALE
Ages:
18 years and above
Trial Updated:
07/08/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Cardiovascular Health
Register for Updates
Therapeutic Mechanisms of Epidural Spinal Cord Stimulation
NCT05556902
Recruiting
The purpose of this study in patients undergoing routine care epidural spinal cord stimulation (SCS) is to determine 1) whether SCS reduces arterial blood pressure (BP) in patients which chronic low back pain and hypertension, 2) whether higher baseline BP (i.e., hypertension) predicts reductions in pain following SCS, and finally 3) whether different SCS waveforms elicits stimulus-evoked compound action potentials (ECAPs) in spinal cord and at the cortex (electroencephalography, and magnetoench... Read More
Gender:
ALL
Ages:
Between 18 years and 89 years
Trial Updated:
07/08/2024
Locations: University of Alabama at Birmingham, Birmingham, Alabama
Conditions: Blood Pressure, Low Back Pain, Hypertension
Register for Updates
Safety and Efficacy of Corneal Cross-linking in Subjects With Keratoconus
NCT05314738
Recruiting
Clinical Trial to Evaluate the Safety and Efficacy of Corneal Cross-linking in Subjects with Keratoconus.
Gender:
ALL
Ages:
Between 18 years and 55 years
Trial Updated:
07/04/2024
Locations: Glaukos Investigative Site, Dothan, Alabama
Conditions: Progressive Keratoconus
Register for Updates