Arkansas is currently home to 726 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Little Rock, Jonesboro, Hot Springs and Fayetteville. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
Non-Invasive Diagnosis of Pediatric Pulmonary Invasive Mold Infections
Recruiting
This study will establish a non-invasive diagnostic approach and evaluate clinical outcomes for children at high-risk for pulmonary invasive fungal infection (PIFI).
Gender:
All
Ages:
Between 120 days and 21 years
Trial Updated:
01/29/2024
Locations: Arkansas Children's Research Institute, Little Rock, Arkansas
Conditions: Pulmonary Invasive Aspergillosis, Pulmonary Invasive Fungal Infections
Collecting and Storing Tissue From Young Patients With Cancer
Recruiting
This laboratory study is collecting and storing tissue, blood, and bone marrow samples from young patients with cancer. Collecting and storing samples of tissue, blood, and bone marrow from patients with cancer to study in the laboratory may help doctors learn more about changes that may occur in DNA and identify biomarkers related to cancer.
Gender:
All
Ages:
21 years and below
Trial Updated:
01/29/2024
Locations: Arkansas Children's Hospital, Little Rock, Arkansas
Conditions: Acute Lymphoblastic Leukemia, Rhabdomyosarcoma, Acute Myeloid Leukemia, Central Nervous System Neoplasm, Ewing Sarcoma, Germ Cell Tumor, Leukemia, Lymphoma, Malignant Neoplasm, Neuroblastoma, Osteosarcoma, Retinoblastoma, Rhabdoid Tumor, Soft Tissue Sarcoma
A Prospective Single-Arm Multicenter StuDy of the BarE TEmporary SPur StEnt System foR the tREatment of Vascular Lesions Located in the infrapoplitEal Arteries beLow the Knee (DEEPER REVEAL)
Recruiting
This is a prospective, multicenter, single arm study designed to evaluate the safety and efficacy of the Temporary Bare Spur Stent System (Spur Stent System).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/26/2024
Locations: St. Bernards Heart and Vascular, Jonesboro, Arkansas
Conditions: Peripheral Arterial Disease, Critical Limb Ischemia
A Phase 3 Study Evaluating Efficacy and Safety of Lanifibranor Followed by an Active Treatment Extension in Adult Patients With (NASH) and Fibrosis Stages F2 and F3 ( NATiV3 )
Recruiting
This Phase 3 study is conducted to evaluate lanifibranor in adults with NASH and liver fibrosis histological stage F2 or F3
Gender:
All
Ages:
18 years and above
Trial Updated:
01/24/2024
Locations: ARcare Center for Clinical Research - Conway, Conway, Arkansas
Conditions: NASH - Nonalcoholic Steatohepatitis
Cobimetinib In Extracranial Arteriovenous Malformations (COBI-AVM Study)
Recruiting
The purpose of this open-label study is to evaluate the safety and efficacy of cobimetinib in extracranial AVM.
Gender:
All
Ages:
Between 2 years and 80 years
Trial Updated:
01/23/2024
Locations: Arkansas Children's Hospital, Little Rock, Arkansas
Conditions: Arteriovenous Malformations (Extracranial)
Oral Nutritional Supplementation in Children at Risk of Undernutrition
Recruiting
The objective of this randomized, controlled trial is to evaluate the effects of consuming a pediatric oral nutritional supplement (ONS) plus dietary counseling for 120 days on anthropometric growth, strength, and nutritional status, compared with dietary counseling alone in undernourished children in the United States.
Gender:
All
Ages:
Between 36 months and 107 months
Trial Updated:
01/22/2024
Locations: HealthStar Research Glenwood, Glenwood, Arkansas
Conditions: Undernutrition
A Study of U3-1402 (Patritumab Deruxtecan) in Subjects With Metastatic Breast Cancer
Recruiting
This study is to evaluate safety and efficacy of an antibody drug conjugate U3-1402 (patritumab deruxtecan) in patients with locally advanced or metastatic breast cancer (MBC).
Gender:
All
Ages:
18 years and above
Trial Updated:
01/22/2024
Locations: Highlands Oncology Group, Springdale, Arkansas
Conditions: Metastatic Breast Cancer, Locally Advanced Breast Cancer
Enasidenib for the Treatment of Relapsed or Refractory Acute Myeloid Leukemia Patients With an IDH2 Mutation
Recruiting
This trial studies the side effects of enasidenib and to see how well it works in treating patients with acute myeloid leukemia that has come back after treatment (relapsed) or has been difficult to treat with chemotherapy (refractory). Patients must also have a specific genetic change, also called a mutation, in a protein called IDH2. Enasidenib may stop the growth of cancer cells by blocking the mutated IDH2 protein, which is needed for cell growth.
Gender:
All
Ages:
Between 24 months and 21 years
Trial Updated:
01/19/2024
Locations: Arkansas Children's Hospital, Little Rock, Arkansas
Conditions: Recurrent Acute Myeloid Leukemia, Refractory Acute Myeloid Leukemia
RxSight Light Adjustable Lens and Light Delivery Device New Enrollment Study
Recruiting
The primary objective of this study is to conduct a post-approval study which compares the LAL to a monofocal control IOL for safety outcomes.
Gender:
All
Ages:
Between 40 years and 80 years
Trial Updated:
01/18/2024
Locations: Vold Vision, Fayetteville, Arkansas
Conditions: Aphakia, Cataract
A Study to Evaluate Safety, Efficacy and Pharmacokinetics of Paricalcitol For Treatment of Secondary Hyperparathyroidism (SHPT) in Pediatric Participants With Stage 5 Chronic Kidney Disease (CKD)
Recruiting
The main objective of this study is to evaluate the safety, efficacy and pharmacokinetics of paricalcitol oral solution in pediatric participants of ages 0 to 9 years with SHPT associated with stage 5 CKD receiving Peritoneal Dialysis (PD) or Hemodialysis (HD). The 24-week study is divided into two 12-week dosing periods (Dosing Period 1 followed by Dosing Period 2).
Gender:
All
Ages:
Between 0 years and 9 years
Trial Updated:
01/17/2024
Locations: Arkansas Children's Hospital /ID# 225417, Little Rock, Arkansas
Conditions: Chronic Kidney Disease (CKD), Secondary Hyperparathyroidism (SHPT)
Improving Safety and Quality of Tracheal Intubation Practice in Pediatric ICUs
Recruiting
Advanced airway interventions are common high risk, high stakes events for children in intensive care units (ICU) and emergency departments (ED), with risk for life and health threatening consequences.
Gender:
All
Ages:
All
Trial Updated:
01/17/2024
Locations: Arkansas Children's Hospital, Little Rock, Arkansas
Conditions: Failed or Difficult Intubation, Sequela, Intubation; Difficult, Intubation Complication
A Study to Evaluate the Effect of SAGE-718 on Cognitive Function in Participants With Huntington's Disease (HD)
Recruiting
The primary purpose of this study is to evaluate the effect of SAGE-718 on cognitive performance and functioning in participants with HD.
Gender:
All
Ages:
Between 25 years and 65 years
Trial Updated:
01/12/2024
Locations: Sage Investigational Site, Little Rock, Arkansas
Conditions: Huntington's Disease