Arkansas is currently home to 726 active clinical trials, seeking participants for engagement in research studies. These trials take place at a variety of cities in the state, including Little Rock, Jonesboro, Hot Springs and Fayetteville. Whether you're a healthy volunteer interested in paid medical research or someone seeking trials related to a specific condition, the state offers a diverse array of opportunities in your vicinity.
FRESH Delivers: An Innovative Approach to Reducing Tobacco Use Among Rural/Black African American Smokers
Recruiting
The long-term goal of FRESH Delivers is to fill a critical gap in knowledge on the role of a home-based food delivery social intervention in the elimination of tobacco-caused cancer health disparities. The central hypothesis is that smokers who receive real-time video-based motivational counseling and home-based food deliveries will have greater cotinine-verified 7-day point prevalence abstinence than those who receive real-time video-based motivational counseling alone or home food delivery alo... Read More
Gender:
All
Ages:
Between 21 years and 75 years
Trial Updated:
01/02/2024
Locations: University of Arkansas for Medical Sciences, Little Rock, Arkansas
Conditions: Tobacco Cessation, Tobacco Dependence, Food Security
Persona Revision Knee System Outcomes
Recruiting
The study will evaluate the performance, clinical benefits and safety of the Persona Revision Knee System in patients who have received primary or revision total knee arthroplasty (TKA) treatment. This will be done using a multicenter, single-arm, consecutive series, retrospective cohort study with prospective follow-up.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/27/2023
Locations: Advanced Orthopaedic Specialists, Fayetteville, Arkansas
Conditions: Arthroplasty Complications, Infection, Knee Disease, Knee Osteoarthritis
Nutritional Therapy for Delirium in Elderly Hospitalized Subjects
Recruiting
The investigators have developed a proprietary blend of amino acids that they think will help to prevent or reduce the severity of delirium in older people who are hospitalized for certain infections. In this study, up to 45 people will be enrolled. 15 will be asked to drink this blend twice a day for up to 4 days, and 15 will drink a placebo (sugar water) for the same time period. The other 15 subjects will be non-delirious control subjects who do not consume any study products.
Gender:
All
Ages:
60 years and above
Trial Updated:
12/20/2023
Locations: UAMS Center on Aging, Little Rock, Arkansas
Conditions: Subacute Delirium
Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer
Recruiting
The optimal treatment for Stage I or Stage IIA non-small cell lung cancer (NSCLC) remains controversial. Radiographic surveillance alone has been recommended for stage I and stage IIA patients after the tumor is removed surgically from the lung, and this standard has been based on the fact that no previous clinical trial has demonstrated a benefit for Stage I or Stage IIA NSCLC patients who receive post-operative chemotherapy. These patients, however, have a substantial risk of death within five... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/20/2023
Locations: Highlands Oncology Group, Springdale, Arkansas
Conditions: Non-Small Cell Lung Cancer
Chemotherapy Before Surgery and Radiation Therapy or Surgery and Radiation Therapy Alone in Treating Patients With Nasal and Paranasal Sinus Cancer That Can Be Removed by Surgery
Recruiting
This randomized phase II trial studies how well chemotherapy before surgery and radiation therapy works compared to surgery and radiation therapy alone in treating patients with nasal and paranasal sinus cancer that can be removed by surgery. Drugs used in chemotherapy, such as docetaxel, cisplatin, and carboplatin work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Radiation therapy uses high-... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/18/2023
Locations: Mercy Hospital Fort Smith, Fort Smith, Arkansas
Conditions: Stage III Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v6 and v7, Stage IVA Nasal Cavity and Paranasal Sinus Squamous Cell Carcinoma AJCC v7
Beginnings Study Follow up
Recruiting
This study will help us learn more about how early infant diet may influence child's growth and development at age 14.
Gender:
All
Ages:
Between 14 years and 14 years
Trial Updated:
12/18/2023
Locations: Arkansas Children's Nutrition Center, Little Rock, Arkansas
Conditions: Healthy
Glowing and Expecting Follow Up
Recruiting
This study will help us learn more about how a mother's health during pregnancy may influence her child's growth and development later in life.
Gender:
All
Ages:
Between 5 years and 14 years
Trial Updated:
12/18/2023
Locations: Arkansas Children's Nutrition Center, Little Rock, Arkansas
Conditions: Healthy
The Fourth Left Atrial Appendage Occlusion Study
Recruiting
LAAOS-4 aims to determine if catheter-based endovascular left atrial appendage occlusion prevents ischemic stroke or systemic embolism in participants with atrial fibrillation, who remain at high risk of stroke, despite receiving ongoing treatment with oral anticoagulation.
Gender:
All
Ages:
18 years and above
Trial Updated:
12/15/2023
Locations: Arrhythmia Research Group, Jonesboro, Arkansas
Conditions: Atrial Fibrillation, Stroke, Ischemic, Systemic Embolism
A Study to Evaluate Analgesic Efficacy and Safety of PRF-110 for Post-surgical Pain
Recruiting
PRF-110 is a viscous, yellowish clear oily solution of ropivacaine intended for administration into surgical sites to provide post-operative analgesia. The pharmacokinetic profile for PRF-110 suggests that its effect could last up to 72 hours. This is A Phase 3, Randomized, Double-Blind, Saline Placebo- and Active-Controlled, Multicenter Study to Evaluate the Analgesic Efficacy and Safety of Intra-operative Administration of PRF-110 Following Unilateral Bunionectomy
Gender:
All
Ages:
18 years and above
Trial Updated:
12/15/2023
Locations: Woodland International Research Group, Little Rock, Arkansas
Conditions: Bunion
Prospective Study of Pregnancy in Women With Cystic Fibrosis
Recruiting
In this study, the investigators aim to evaluate changes in lung function in women with cystic fibrosis (CF) during pregnancy and for 2 years after pregnancy based on exposure to highly effective cystic fibrosis transmembrane conductance regulator (CFTR) modulators.
Gender:
Female
Ages:
16 years and above
Trial Updated:
12/12/2023
Locations: University of Arkansas for Medical Sciences, Little Rock, Arkansas
Conditions: Pregnancy Related, Cystic Fibrosis
The Human Stress Response in a Simulated ED Setting
Recruiting
Stress is important for health. As emergency departments (EDs) are often stressful places, a better understanding of the human stress response is important for understanding how and why patients respond as they do when they come to the ED. Since the investigators cannot take up space in the ED for research, the investigators will instead recruit 20 methamphetamine-using participants who are not currently in treatment and 10 healthy adult matched participants to a simulated ED room in the Univers... Read More
Gender:
All
Ages:
Between 21 years and 55 years
Trial Updated:
12/11/2023
Locations: University of Arkansas for Medical Sciences, Little Rock, Arkansas
Conditions: Stress Physiology, Stress Reaction, Substance Use Disorders, Methamphetamine-dependence, Stress, Emotional
CureDuchenne Link®: A Resource for Research
Recruiting
CureDuchenne link is a data hub comprised of integrated biospecimens, clinical data, and self- and/or caregiver-reported information from participants. Anyone over 4 weeks old who has been diagnosed with DMD or BMD or who is a carrier of DMD or BMD can join. Parents or legal guardians can sign up their child(ren).
Gender:
All
Ages:
4 weeks and above
Trial Updated:
12/08/2023
Locations: Arkansas Children's Hospital, Little Rock, Arkansas
Conditions: Duchenne Muscular Dystrophy, Becker Muscular Dystrophy