There are currently 1013 clinical trials in Aurora, Colorado looking for participants to engage in research studies. Trials are conducted at various facilities, including Children's Hospital Colorado, University of Colorado, University of Colorado Hospital and University of Colorado - Denver. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Anti Inflammatory Lipid Mediators in Asthma Lipid Anti-Inflammtory Mediators in Asthma
NCT03762395
Recruiting
The main purpose of this Phase 2 double blind, placebo controlled crossover clinical study is to demonstrate the efficacy and safety of CXA-10 in obese adult asthmatics. Obesity induces a chronic systemic inflammatory state characterized by impaired adipokine signaling, pro-inflammatory cytokine responses, inflammatory cell activation and enhanced generation of oxidative inflammatory mediators. This impacts the lung, increasing the severity of asthma and its exacerbations. This research will eva... Read More
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/29/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Asthma, Obesity
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A Study to Determine the Efficacy and Safety of Finerenone on Morbidity and Mortality Among Hospitalized Heart Failure Patients
NCT06008197
Recruiting
Finerenone will be compared to placebo to determine efficacy and safety of treatment in patients hospitalized with acute decompensated heart failure (HF) and mildly reduced or preserved left ventricular ejection fraction.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
02/29/2024
Locations: Aurora, CO Investigative Site, Aurora, Colorado
Conditions: Heart Failure, Acute Heart Failure
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The Tether™ - Vertebral Body Tethering System Post Approval Study
NCT04505579
Recruiting
This study is an opportunity to provide continued reasonable assurance of the safety and probable benefit of The Tether HUD. The study will collect long term safety and efficacy information from patients who have had their idiopathic scoliosis treated via anterior vertebral body tethering (AVBT) with The Tether.
Gender:
ALL
Ages:
All
Trial Updated:
02/21/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Scoliosis Idiopathic
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Individualizing Treatment for Asthma in Primary Care
NCT06272370
Recruiting
This is a patient level randomized trial for teenagers and adults with asthma who will be randomized to four arms - enhance usual care, rescue inhaled corticosteroids, azithromycin and both rescue inhaled corticosteroids and azithromycin. Participants in all arms will be offered access to an online asthma symptom monitoring system.
Gender:
ALL
Ages:
Between 12 years and 75 years
Trial Updated:
02/20/2024
Locations: DARTNet Insitute, Aurora, Colorado
Conditions: Asthma, Bronchial Diseases, Respiratory Tract Infections, Lung Diseases, Obstructive, Lung Diseases, Respiratory Hypersensitivity, Immune System Diseases
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Cognitive Behavioral Intervention to Reduce Procedural Anxiety Among Woman With High Risk Pregnancies With Scheduled Cesarean Deliveries
NCT04203082
Recruiting
The goals of this study are to determine the feasibility and efficacy of a brief, single-session cognitive-behavioral intervention for reducing preoperative and postoperative anxiety and for determining satisfaction with the delivery process in pregnant women scheduled for Cesarean delivery due to complications with their pregnancy. This will be done through a combination of psychoeducation and exposure therapy, where the participants will be walked through the steps of a Cesarean delivery in an... Read More
Gender:
FEMALE
Ages:
Between 18 years and 60 years
Trial Updated:
02/20/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Procedural Anxiety, High Risk Pregnancy, Fetal Complications
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Efficacy and Mechanisms of Dapagliflozin in Promoting Kidney Function and Cardiovascular Health in Kidney Transplant Recipients
NCT06140537
Recruiting
Long-term allograft function in kidney transplant recipients (KTRs) remain suboptimal, and graft failure causes significant morbidity and mortality, with cardiovascular disease being the leading cause of death in KTRs and the most common cause of death with a functioning graft. Sodium-glucose cotransporter 2 (SGLT2) inhibitors safely lower cardiovascular and kidney disease risk in the non-transplant population, yet data in KTRs are lacking. This clinical trial seeks to establish the efficacy and... Read More
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/15/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Kidney Transplant; Complications, Vascular Diseases, Diabetes
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A 52-Week Study of the Efficacy and Safety of BLU-5937 in Adults With Refractory Chronic Cough
NCT05599191
Recruiting
This is a randomized, double-blind, placebo-controlled, parallel-arm, Phase 3 study of BLU-5937 in participants with Refractory Chronic Cough (RCC).
Gender:
ALL
Ages:
Between 18 years and 80 years
Trial Updated:
02/14/2024
Locations: Care Access Research, Aurora, Colorado
Conditions: Refractory Chronic Cough
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Longitudinal Study of Urea Cycle Disorders
NCT00237315
Recruiting
Urea cycle disorders (UCD) are a group of rare inherited metabolism disorders. Infants and children with UCD commonly experience episodes of vomiting, lethargy, and coma. The purpose of this study is to perform a long-term analysis of a large group of individuals with various UCDs. The study will focus on the natural history, disease progression, treatment, and outcome of individuals with UCD.
Gender:
ALL
Ages:
All
Trial Updated:
02/10/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Brain Diseases, Metabolic, Inborn, Amino Acid Metabolism, Inborn Errors, Urea Cycle Disorders
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Neuronal Effects of Exercise in Schizophrenia
NCT02455193
Recruiting
This study plans to learn more about how common drugs prescribed to individuals with schizophrenia contribute to weight gain, as well as how exercise and diet impact appetite and the brain's response to food. In this study, the investigators will be evaluating how participants' brains respond to food images as well as asking questions about their food preferences and intake and clinical symptoms. The investigators may also ask participants to complete an exercise or diet intervention to see how... Read More
Gender:
ALL
Ages:
Between 21 years and 70 years
Trial Updated:
02/05/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Schizophrenia
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Fibrostenotic Eosinophilic Esophagitis: Assessment Tools
NCT02453126
Recruiting
This protocol addresses a central hypothesis that fibrostenotic Eosinophilic Esophagitis (EoE) is characterized by abnormal esophageal structure and compliance compared to non fibrostenotic EoE and that distinctive cellular and molecular profiles predict the fibrostenotic phenotype. This study aims to define and assess the changes that occur in the structure and dynamics of the esophageal wall in pediatric Eosinophilic Esophagitis along with characterizing the histologic and molecular patterns i... Read More
Gender:
ALL
Ages:
Between 5 years and 18 years
Trial Updated:
02/02/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Eosinophilic Esophagitis
Register for Updates
Engaging Practices and Communities in the Development of Interventions to Promote HPV Vaccine Uptake
NCT04279964
Recruiting
The overarching goal of this project is to implement Boot Camp Translation (BCT) methodology to translate the guidelines and evidence for human papillomavirus (HPV) vaccine into a practice and provider level intervention designed to improve its acceptability and uptake.
Gender:
ALL
Ages:
Between 9 years and 26 years
Trial Updated:
02/02/2024
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Primary Prevention
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Neuronal and Behavioral Effects of an Implicit Priming Approach to Improve Eating Behaviors in Obesity
NCT05107908
Recruiting
The purpose of this study is to determine how different behavioral interventions designed to alter food perceptions and behaviors affect brain responses to food, eating behaviors, and body weight.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
02/02/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Overweight and Obesity
Register for Updates