There are currently 1022 clinical trials in Aurora, Colorado looking for participants to engage in research studies. Trials are conducted at various facilities, including Children's Hospital Colorado, University of Colorado, University of Colorado Hospital and University of Colorado - Denver. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
A Pilot Factorial Trial of an Integrated Lifestyle Intervention
NCT06116435
Recruiting
This study plans to learn more about the feasibility and acceptability of integrating the Move physical activity support program within an existing lifestyle intervention program.
Gender:
ALL
Ages:
Between 18 years and 65 years
Trial Updated:
05/13/2024
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Physical Inactivity, Overweight and Obesity
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Prevention and Treatment of Frostbite Infection With Antimicrobial Pharmacokinetic Analysis
NCT06266494
Recruiting
This study will compare the effectiveness of two different treatments for preventing infection from frostbite injuries. These two treatments are A) aloe vera and B) long-acting silver wound dressings. The investigators will also study the safety and effectiveness of Dalbavancin, an FDA approved antibiotic used for treating people who develop frostbite wound infections, as well as evaluate how frostbite damage to individuals' bodies may affect how fast their kidney clear drugs from their systems.
Gender:
ALL
Ages:
Between 18 years and 99 years
Trial Updated:
05/10/2024
Locations: University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado
Conditions: Frostbite
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Randomized Trial of Fresh Frozen Plasma Versus Albumin in Acute Burn Resuscitation
NCT05069922
Recruiting
The investigators propose a prospective randomized trial to study fresh frozen plasma (FFP) versus albumin to determine the optimal colloid in burn resuscitations. This work addresses both FY20 focus areas, prolonged field care (PFC) and en route care, along with mitigating secondary effects of acute intervention, such as prevention of over resuscitation. Future military conflicts anticipate more extensive burn and blast injuries, and delayed evacuation. Therefore, the direct comparison of collo... Read More
Gender:
ALL
Ages:
Between 18 years and 100 years
Trial Updated:
05/10/2024
Locations: University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado
Conditions: Burns
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Skeletal Effects of Chronic Night Shift
NCT05091021
Recruiting
The specific aim of this observational study is to characterize changes in bone turnover makers (BTMs), bone mineral density (BMD), and bone microarchitecture in a cohort of nurses during their first year of night compared to day shift work. The hypothesis is that night shift nurses will have poorer bone health indices at one year compared to day shift nurses.
Gender:
ALL
Ages:
Between 20 years and 50 years
Trial Updated:
05/10/2024
Locations: CU Anschutz, Aurora, Colorado
Conditions: Osteoporosis, Circadian Rhythm Sleep Disorder, Shift Work Type
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A Long-term, Post-marketing Safety Study of Palynziq in Patients With PKU (PALace)
NCT05813678
Recruiting
This is a 10-year multi-center, global, observational study to further characterize the safety profile of pegvaliase, including hypersensitivity reactions, long-term safety and tolerability, and the effectiveness of the additional risk minimization measures (aRMMs) (European Union (EU) only) in subjects receiving pegvaliase for the treatment of PKU. Subjects for whom a clinical decision has been made that they will receive pegvaliase to treat their PKU within 30 days following the date of enroll... Read More
Gender:
ALL
Ages:
All
Trial Updated:
05/10/2024
Locations: University of Colorado, Aurora, Colorado
Conditions: Phenylketonuria (PKU)
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Premature Discontinuation of Contraceptive Implants
NCT04828824
Recruiting
To compare rates of etonogestrel implant discontinuation in implant initiators who are given advance provision of combined oral contraceptive pills (COCs) and a bleeding rescue regimen (COCR intervention) to participants given standard counseling (comparator).
Gender:
FEMALE
Ages:
Between 14 years and 23 years
Trial Updated:
05/09/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Contraception Behavior
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Longitudinal Study of Intra-Uterine Growth Restriction
NCT02382601
Recruiting
The investigation will employ a longitudinal approach in which every fetus diagnosed to be SGA (Small for Gestational Age ) will be studied at frequent intervals with sophisticated imaging techniques to assess subtle physiologic changes in the brain, heart, and placenta over time. These findings will be correlated with neurological and cardiovascular function in the newborn and early childhood. This research initiative should yield diagnostic and therapeutic templates that will improve the quali... Read More
Gender:
FEMALE
Ages:
Between 18 years and 45 years
Trial Updated:
05/09/2024
Locations: University of Colorado Denver Anschutz Medical Campus, Aurora, Colorado
Conditions: IUGR, Pregnancy
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Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others
NCT01193075
Recruiting
This is an observational longitudinal study to determine the natural history and genotype-phenotype correlations of disease causing mutations in Charcot Marie Tooth disease (CMT) type 1B (CMT1B), 2A (CMT2A), 4A (CMT4A), and 4C (CMT4C). The investigators will also be determine the capability of the newly developed CMT Pediatric Scale (CMT Peds scale) and the Minimal Dataset to measure impairment and perform longitudinal measurements in patients with multiple forms of CMT over a five year window
Gender:
ALL
Ages:
All
Trial Updated:
05/09/2024
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Charcot Marie Tooth Disease
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Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2
NCT01193088
Recruiting
This project includes two projects. One is looking for new genes that cause Charcot Marie Tooth disease (CMT). The other is looking for genes that do not cause CMT, but may modify the symptoms a person has.
Gender:
ALL
Ages:
All
Trial Updated:
05/09/2024
Locations: University of Colorado Hospital, Aurora, Colorado
Conditions: Charcot-Marie-Tooth Disease, Type Ia (Disorder), HMSN
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Study of TL-895 in Subjects With Myelofibrosis or Indolent Systemic Mastocytosis
NCT04655118
Recruiting
This study evaluates TL-895, a potent, orally-available and highly selective irreversible tyrosine kinase inhibitor for the treatment of Myelofibrosis (Cohorts 1-3) or Indolent Systemic Mastocytosis (Cohort 5). Participants must be diagnosed with Myelofibrosis and be relapsed/refractory (e.g., having failed prior therapy), intolerant, or ineligible to receive JAKi treatment, or be diagnosed with Indolent Systemic Mastocytosis.
Gender:
ALL
Ages:
18 years and above
Trial Updated:
05/08/2024
Locations: University of Colorado - Aurora Cancer Center, Aurora, Colorado
Conditions: Myelofibrosis, Indolent Systemic Mastocytosis
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Technology-assisted Language Intervention (TALI)
NCT04857255
Recruiting
This study is testing the effectiveness of augmentative and alternative communication technology among deaf or hard of hearing children for improving language development. Children will be randomized to receive either the technology intervention or treatment as usual
Gender:
ALL
Ages:
Between 3 years and 10 years
Trial Updated:
05/07/2024
Locations: Children's Hospital of Colorado, Aurora, Colorado
Conditions: Hearing Loss, Bilateral, Language Development
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The eXtroardinarY Babies Study: Natural History of Health and Neurodevelopment in Infants and Young Children With Sex Chromosome Trisomy
NCT03396562
Recruiting
This study is designed to research the natural history of neurodevelopment, health and early hormonal function in infants with XXY/Klinefelter syndrome, XYY, XXX and other sex chromosome variations in an effort to identify early predictors of developmental and health outcomes. The Investigators will also evaluate different developmental screening tools in infants with sex chromosome variations so the investigators can develop recommendations for pediatrician caring for infants and young children... Read More
Gender:
ALL
Ages:
Between 6 weeks and 13 months
Trial Updated:
05/07/2024
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Klinefelter Syndrome, Trisomy X, XYY Syndrome, XXXY and XXXXY Syndrome, Xxyy Syndrome, Xyyy Syndrome, Xxxx Syndrome, Xxxxx Syndrome, Xxxyy Syndrome, Xxyyy Syndrome, Xyyyy Syndrome, Male With Sex Chromosome Mosaicism
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