There are currently 1050 clinical trials in Aurora, Colorado looking for participants to engage in research studies. Trials are conducted at various facilities, including Children's Hospital Colorado, University of Colorado, University of Colorado Hospital and University of Colorado- Denver. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Early Iron Exposure on the Gut Microbiota in Young Infants
NCT03828708
Recruiting
This study will look at the amount of iron in infant formula and how that affects a child's gut development. The children of mothers who plan to formula feed their children will be randomized to receive either high iron or low iron formula from birth until 4 months of age. Infants will consume only the study provided formula during enrollment. Blood and stool samples will be collected at birth and end of study to measure the effects of the iron exposure. The overall object is to compare high iro... Read More
Gender:
All
Ages:
Between 1 day and 4 months
Trial Updated:
02/01/2023
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Infant Development
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The Effects of Early Complementary Feeding on Growth, Neurodevelopment, Sleep and Gut Health
NCT04137445
Recruiting
The overall objective of this project is to understand how consuming a prescribed diet of different infant foods (which may contain cereals,fruits, vegetables, meats, dairy) during the time of early complementary feeding (~5 to 12 months) in breastfed infants has on growth trajectories, neurodevelopment and sleep patterns in relation to gut microbiota, compared with a traditional diet that is usually provided in the home to infants. The three primary aims include: Aim 1: Identify the effects t... Read More
Gender:
All
Ages:
Between 5 months and 6 months
Trial Updated:
02/01/2023
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Linear Growth, Neurodevelopment, Gut Microbiome
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The Pediatric Spine Foundation
NCT02540915
Recruiting
The Pediatric Spine Foundation is a registry designed to assist spine surgeons to efficiently identify and track patients with chest wall and spinal disorders.
Gender:
All
Ages:
17 years and below
Trial Updated:
02/01/2023
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Chest Wall and Spinal Disorders
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Obesity, Metabolic Dysregulation and the Airway Epithelium in Asthmatics
NCT03215836
Recruiting
The objective of this pilot study is to determine whether obesity and metabolic syndrome are in fact synergistic in relation to airway nitric oxide (NO) biology. To do so, the investigators want to determine how obesity and the metabolic syndrome relate to metabolism in bronchial airway epithelial cells and the nasal epithelium.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/01/2023
Locations: University of Colorado, Aurora, Colorado
Conditions: Asthma, Obesity, Metabolic Syndrome
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An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study
NCT04108130
Recruiting
Postoperative pulmonary complications (PPCs) are a major cause of morbidity and mortality in surgical patients. National estimates suggest 1,062,000 PPCs per year, with 46,200 deaths, and 4.8 million additional days of hospitalization. The objective of the study is to develop and implement perioperative strategies to eliminate PPCs in abdominal surgery, the field with the largest absolute number of PPCs. We will conduct a randomized controlled pragmatic trial in 750 studied participants. The eff... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/01/2023
Locations: University of Colorado, Anschutz Medical Campus, Aurora, Colorado
Conditions: Postoperative Pulmonary Complications
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Blueberry Intake and Infant Gut Health
NCT05006989
Recruiting
The objective of this project is to investigate the effects of blueberries on gut microbiota, inflammation and innate immunity in breastfed infants during early complementary feeding (~5 to 12 months of age).
Gender:
All
Ages:
Between 4 months and 5 months
Trial Updated:
02/01/2023
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Infant Development
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Improving Outcomes Using Technology for Children Who Are DHH
NCT02998164
Recruiting
This study evaluates the efficacy of using augmentative and alternative communication (AAC) technology for enhancing language development in children who are deaf or hard of hearing. Half of the participants will receive AAC technology with their speech and language therapy and half will continue with their usual care models.
Gender:
All
Ages:
Between 3 years and 10 years
Trial Updated:
01/26/2023
Locations: Children's Hospital of Colorado, Aurora, Colorado
Conditions: Hearing Loss, Language Development, Social Behavior
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Efficacy of EsoGuard Assay on Esophageal Surface Cells Collected With EsoCheck vs EGD for the Diagnosis of BE or EAC
NCT04295811
Recruiting
The study will assess the performance of the combined system, i.e., the use of the EsoGuard assay (lab developed test) on cells collected using the EsoCheck (501k cleared device) to detect Barrett's Esophagus (BE), with or without dysplasia, and esophageal adenocarcinoma (EAC) as compared to Esophagogastroduodenoscopy (EGD) plus biopsies in both confirmed cases of BE/EAC and in controls (subjects without a prior diagnosis but undergoing screening for BE/EAC)
Gender:
Male
Ages:
50 years and above
Trial Updated:
01/23/2023
Locations: Lucid Investigative Site, Aurora, Colorado
Conditions: Barrett Esophagus, Esophageal Adenocarcinoma, Barretts Esophagus With Dysplasia, Barrett's Esophagus Without Dysplasia
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The Effects of IV vs Oral Dexamethasone on Postoperative Nausea, Vomiting, and Pain
NCT04563494
Recruiting
The hypothesis being tested in this study is that perioperative oral administration of dexamethasone, when compared to intravenous (IV) administration, offers a similar reduction in postoperative nausea and vomiting (PONV), and reduction in postoperative pain in pediatric patients undergoing tonsillectomy with or without adenoidectomy and/or tympanostomy tube placement. The specific aim of this study is to demonstrate non-inferiority of oral dexamethasone when compared to IV dexamethasone, given... Read More
Gender:
All
Ages:
Between 3 years and 7 years
Trial Updated:
01/17/2023
Locations: Children's Hospital of Colorado, Aurora, Colorado
Conditions: Nausea and Vomiting, Postoperative
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SARC041: Study of Abemaciclib Versus Placebo in Patients With Advanced Dedifferentiated Liposarcoma
NCT04967521
Recruiting
This is a Phase 3 randomized double-blind study of abemaciclib versus placebo. Patients with progression of disease will cross over to open label abemaciclib.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/11/2023
Locations: University of Colorado Cancer Center, Anschutz Medical Campus, Aurora, Colorado
Conditions: Advanced Dedifferentiated Liposarcoma
Register for Updates
Effects of Complementary Feeding on Infant Growth and Gut Health
NCT05012930
Recruiting
This study plans to learn more about how consuming different foods during the time of early complementary feeding (~5 to 12 months) affects growth and the development of bacteria living inside your baby's gut. The results from this study will potentially help to support future recommendations and dietary guidance for infant feeding practices. The three primary aims include: Aim 1. Identify the impact of dietary patterns with different protein-rich foods on infant growth. Aim 2. Identify the i... Read More
Gender:
All
Ages:
Between 4 months and 50 months
Trial Updated:
01/09/2023
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Gut Microbiome, Linear Growth
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Testing the Use of Targeted Treatment (AMG 510) for KRAS G12C Mutated Advanced Non-squamous Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)
NCT04625647
Recruiting
This phase II Lung-MAP treatment trial studies the effect of AMG 510 in treating non-squamous non-small cell lung cancer that is stage IV or has come back (recurrent) and has a specific mutation in the KRAS gene, known as KRAS G12C. Mutations in this gene may cause the cancer to grow. AMG 510, a targeted treatment against the KRAS G12C mutation, may help stop the growth of tumor cells.
Gender:
All
Ages:
18 years and above
Trial Updated:
11/09/2022
Locations: Rocky Mountain Cancer Centers-Aurora, Aurora, Colorado +1 locations
Conditions: Lung Adenocarcinoma, Lung Non-Small Cell Carcinoma, Recurrent Lung Non-Squamous Non-Small Cell Carcinoma, Stage IV Lung Cancer AJCC v8, Stage IVA Lung Cancer AJCC v8, Stage IVB Lung Cancer AJCC v8
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