There are currently 1053 clinical trials in Aurora, Colorado looking for participants to engage in research studies. Trials are conducted at various facilities, including Children's Hospital Colorado, University of Colorado, University of Colorado Hospital and University of Colorado- Denver. Whether you're a healthy volunteer looking to participate in paid medical research or seeking trials related to a specific condition, the city provides a diverse range of opportunities near you.
Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS
NCT05267821
Recruiting
The TRIPS study is a prospective, multi-center, double-blind, adaptively randomized, placebo-controlled clinical trial of the drug anakinra for reversal of moderate to severe hyperinflammation in children with sepsis-induced multiple organ dysfunction syndrome (MODS).
Gender:
All
Ages:
Between 1 day and 17 years
Trial Updated:
02/07/2023
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)
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The PROMISE Study: Duavee in Women With DCIS
NCT02694809
Recruiting
The main purpose of this study is to determine if taking the study drug, conjugated estrogens/bazedoxifene (Duavee®) causes any changes in the proliferation markers within the breast tissue of the study subjects. The study drug is approved by the US Food and Drug Administration in healthy postmenopausal women to treat certain symptoms of menopause such as hot flashes. Since it is not approved in women with DCIS, its use in this study is experimental. This study will also look at whether taking t... Read More
Gender:
Female
Ages:
Between 18 years and 79 years
Trial Updated:
02/06/2023
Locations: University of Colorado at Denver/ Department of Surgery, Aurora, Colorado
Conditions: Ductal Breast Carcinoma In Situ, Postmenopausal
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EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study
NCT05610787
Recruiting
The purpose of this study is to evaluate the device performance and monitor the safety and effectiveness of the Berlin Heart EXCOR Active Driving System while being used with the approved EXCOR Pediatric Ventricular Assist Device. EXCOR Active Driving System is intended for use with the approved EXCOR Pediatric VAD. The EXCOR Pediatric VAD is intended to provide mechanical circulatory support as a bridge to cardiac transplantation for pediatric patients. Pediatric candidates with severe isolat... Read More
Gender:
All
Ages:
21 years and below
Trial Updated:
02/06/2023
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Heart Failure, Transplant; Failure, Heart, Congenital Heart Disease
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Outcomes for Lumbar Decompressions With Use of Liposomal Bupivicaine
NCT04066296
Recruiting
Evaluate the benefit of using liposomal bupivicaine in lumbar laminectomies in terms of length of stay, IV narcotic use, 30-day narcotic use, visual analog score (VAS) and 30-day readmissions
Gender:
All
Ages:
18 years and above
Trial Updated:
02/02/2023
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Lumbar Spinal Stenosis
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Risk Factors in Early Multiple Sclerosis
NCT03586986
Recruiting
The central hypothesis of this protocol is that it is possible, using First Degree Relatives (FDRs) of patients with Multiple Sclerosis (MS) and assessing a variety of both known and unknown risk factors for MS, to define a risk algorithm for earliest signs of development of MS. The plan will be to do an abbreviated brain Magnetic Resonance Imaging (MRI) scan in asymptomatic, young FDRs, analyze blood for a variety of immunological, genetic, neuroaxonal damage, metabolic, viral serology and othe... Read More
Gender:
All
Ages:
Between 18 years and 30 years
Trial Updated:
02/02/2023
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Multiple Sclerosis, Magnetic Resonance Imaging, Biomarkers, Clinically Isolated Syndrome, Radiologically Isolated Syndrome
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The Pediatric Spine Foundation
NCT02540915
Recruiting
The Pediatric Spine Foundation is a registry designed to assist spine surgeons to efficiently identify and track patients with chest wall and spinal disorders.
Gender:
All
Ages:
17 years and below
Trial Updated:
02/01/2023
Locations: Children's Hospital Colorado, Aurora, Colorado
Conditions: Chest Wall and Spinal Disorders
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Obesity, Metabolic Dysregulation and the Airway Epithelium in Asthmatics
NCT03215836
Recruiting
The objective of this pilot study is to determine whether obesity and metabolic syndrome are in fact synergistic in relation to airway nitric oxide (NO) biology. To do so, the investigators want to determine how obesity and the metabolic syndrome relate to metabolism in bronchial airway epithelial cells and the nasal epithelium.
Gender:
All
Ages:
Between 18 years and 65 years
Trial Updated:
02/01/2023
Locations: University of Colorado, Aurora, Colorado
Conditions: Asthma, Obesity, Metabolic Syndrome
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The Effects of Early Complementary Feeding on Growth, Neurodevelopment, Sleep and Gut Health
NCT04137445
Recruiting
The overall objective of this project is to understand how consuming a prescribed diet of different infant foods (which may contain cereals,fruits, vegetables, meats, dairy) during the time of early complementary feeding (~5 to 12 months) in breastfed infants has on growth trajectories, neurodevelopment and sleep patterns in relation to gut microbiota, compared with a traditional diet that is usually provided in the home to infants. The three primary aims include: Aim 1: Identify the effects t... Read More
Gender:
All
Ages:
Between 5 months and 6 months
Trial Updated:
02/01/2023
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Linear Growth, Neurodevelopment, Gut Microbiome
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Early Iron Exposure on the Gut Microbiota in Young Infants
NCT03828708
Recruiting
This study will look at the amount of iron in infant formula and how that affects a child's gut development. The children of mothers who plan to formula feed their children will be randomized to receive either high iron or low iron formula from birth until 4 months of age. Infants will consume only the study provided formula during enrollment. Blood and stool samples will be collected at birth and end of study to measure the effects of the iron exposure. The overall object is to compare high iro... Read More
Gender:
All
Ages:
Between 1 day and 4 months
Trial Updated:
02/01/2023
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Infant Development
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Blueberry Intake and Infant Gut Health
NCT05006989
Recruiting
The objective of this project is to investigate the effects of blueberries on gut microbiota, inflammation and innate immunity in breastfed infants during early complementary feeding (~5 to 12 months of age).
Gender:
All
Ages:
Between 4 months and 5 months
Trial Updated:
02/01/2023
Locations: University of Colorado Anschutz Medical Campus, Aurora, Colorado
Conditions: Infant Development
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An Anesthesia-Centered Bundle to Reduce Postoperative Pulmonary Complications: The PRIME-AIR Study
NCT04108130
Recruiting
Postoperative pulmonary complications (PPCs) are a major cause of morbidity and mortality in surgical patients. National estimates suggest 1,062,000 PPCs per year, with 46,200 deaths, and 4.8 million additional days of hospitalization. The objective of the study is to develop and implement perioperative strategies to eliminate PPCs in abdominal surgery, the field with the largest absolute number of PPCs. We will conduct a randomized controlled pragmatic trial in 750 studied participants. The eff... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
02/01/2023
Locations: University of Colorado, Anschutz Medical Campus, Aurora, Colorado
Conditions: Postoperative Pulmonary Complications
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Improving Outcomes Using Technology for Children Who Are DHH
NCT02998164
Recruiting
This study evaluates the efficacy of using augmentative and alternative communication (AAC) technology for enhancing language development in children who are deaf or hard of hearing. Half of the participants will receive AAC technology with their speech and language therapy and half will continue with their usual care models.
Gender:
All
Ages:
Between 3 years and 10 years
Trial Updated:
01/26/2023
Locations: Children's Hospital of Colorado, Aurora, Colorado
Conditions: Hearing Loss, Language Development, Social Behavior
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