There are currently 28 active clinical trials seeking participants for Alzheimer's Disease research studies. The states with the highest number of trials for Alzheimer's Disease participants are Florida, California, New York and Arizona.
Tau PET/CT Imaging in the Mismatch Prospective Cohort Study (MPC-TAU)
NCT05658913
Recruiting
To collect Tau PET/CT imaging in older adults diagnosed with Mild Cognitive Impairment (MCI) or Alzheimer's Disease (AD) in the Mismatch Prospective Cohort Study (MPC-Tau) study to determine relationship to clinical, cognitive, and other biomarker data. Findings from this study will likely provide insight into the phenotypic variability of Alzheimer's Disease and other related pathologies.
Gender:
All
Ages:
Between 18 years and 120 years
Trial Updated:
04/23/2024
Locations: Massachusetts General Hospital, Boston, Massachusetts +1 locations
Conditions: Alzheimer's Disease
Register for Updates
Dominantly Inherited Alzheimer Network (DIAN)
NCT00869817
Recruiting
The purpose of this study is to identify potential biomarkers that may predict the development of Alzheimer's disease in people who carry an Alzheimer's mutation.
Gender:
All
Ages:
18 years and above
Trial Updated:
04/23/2024
Locations: Mayo Clinic Jacksonville, Jacksonville, Florida +23 locations
Conditions: Alzheimer's Disease
Register for Updates
A Long-term Extension Study to Evaluate Safety, Tolerability, and Efficacy of AL002 in Alzheimer's Disease
NCT05744401
Recruiting
A long-term extension study to evaluate the safety, tolerability, and efficacy of AL002 in participants with Early Alzheimer's Disease.
Gender:
All
Ages:
Between 50 years and 85 years
Trial Updated:
04/15/2024
Locations: Banner Alzheimer's Institute, Phoenix, Arizona +26 locations
Conditions: Alzheimer's Disease
Register for Updates
Methodology Issues in a Tailored Light Treatment for Persons With Dementia - Aim 2
NCT05837819
Recruiting
Aim 2 will investigate the effect of 3 different light exposure lengths on sleep, mood and agitation in persons with Alzheimer's disease. Participants will be randomly assigned to one of three conditions of light exposure: 1) 2-h morning light exposure; 2) 4-h morning light exposure; and 3) all day light exposure.
Gender:
All
Ages:
65 years and above
Trial Updated:
04/09/2024
Locations: Icahn School of Medicine at Mount Sinai, Albany, New York +1 locations
Conditions: Alzheimer's Disease, Sleep Disturbance
Register for Updates
Safety and Target Engagement of Centella Asiatica in Cognitive Impairment
NCT05591027
Recruiting
This clinical trial is focused on determining whether biological signatures of target engagement by a Centella asiatica water extract product administered orally for 6 weeks can be measured in comparison to placebo. This study will also assess the safety and tolerability of the Centella asiatica water extract product.
Gender:
All
Ages:
Between 65 years and 85 years
Trial Updated:
04/05/2024
Locations: Oregon Health & Science University, Portland, Oregon
Conditions: Mild Cognitive Impairment, Alzheimer's Disease
Register for Updates
A Light Exposure Tracker Designed to Improve Circadian Rhythms - Aim 1
NCT06356337
Recruiting
The purpose of this research study is to investigate the relationship between light and circadian rhythms. Twenty healthy older adults will be recruited to participate in a randomized, cross-over study, where an active lighting intervention designed to maintain entrainment and a control intervention designed not to entrain will be tested.
Gender:
All
Ages:
55 years and above
Trial Updated:
04/04/2024
Locations: Light and Health Research Center, Menands, New York
Conditions: Alzheimer's Disease, Mild Cognitive Impairment
Register for Updates
Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease
NCT06079190
Recruiting
The aim of this study is to assess the efficacy and safety of GSK4527226 in participants with early Alzheimer's Disease (AD) (including mild cognitive impairment [MCI] and mild dementia due to AD) of 2 dose levels of GSK4527226 compared to placebo.
Gender:
All
Ages:
Between 50 years and 85 years
Trial Updated:
02/12/2024
Locations: GSK Investigational Site, San Diego, California +103 locations
Conditions: Alzheimer's Disease
Register for Updates
The Long-term Impact of a Light Intervention on Sleep and Cognition in Mild Cognitive Impairment
NCT04073628
Recruiting
To investigate the impact of a long-term light treatment intervention on sleep physiology and memory in mild cognitively impaired and mild Alzheimer's disease patients living at home. The goal is also to measure the impact of the lighting intervention on caregivers' sleep, cognition, depression, and quality of life.
Gender:
All
Ages:
50 years and above
Trial Updated:
02/06/2024
Locations: Icahn School of Medicine at Mount Sinai, Albany, New York +1 locations
Conditions: Mild Cognitive Impairment, Alzheimer's Disease
Register for Updates
Retinal Imaging in Neurodegenerative Disease
NCT03233646
Recruiting
This study aims to develop and evaluate biomarkers using non-invasive optical coherence tomography (OCT) and OCT angiography (OCTA) as well as ultra-widefield (UWF) fundus photography to assess the structure and function of the retinal and choroidal microvasculature and structure in persons with mild cognitive impairment (MCI) and Alzheimer's Disease (AD), Parkinson's Disease (PD), or other neurodegenerative disease, diseases as outlined.
Gender:
All
Ages:
18 years and above
Trial Updated:
01/29/2024
Locations: Duke University Medical Center, Durham, North Carolina
Conditions: Mild Cognitive Impairment, Multiple Sclerosis, Huntington Disease, Neuro-Degenerative Disease, Alzheimer's Disease, Parkinson's Disease, Lewy Body Dementia, Frontotemporal Dementia, Amyotrophic Lateral Sclerosis (ALS), APOE-4 Positive, Traumatic Brain Injury, Concussion, Post-Traumatic Stress Disorder, Down Syndrome, Normal Cognition
Register for Updates
A Community-Based Screening Program to Identify Participants at High Risk for Amyloid Pathology
NCT06043700
Recruiting
The primary purpose of this study is to identify participants with or without symptoms of Alzheimer's Disease (AD) that are at high risk for brain amyloid pathology using blood-based biomarkers.
Gender:
All
Ages:
Between 50 years and 80 years
Trial Updated:
11/21/2023
Locations: Eisai Site #1, Lady Lake, Florida +1 locations
Conditions: Alzheimer's Disease
Register for Updates
Alzheimer's Prevention Registry: A Program to Accelerate Enrollment Into Studies
NCT02022943
Recruiting
The Alzheimer's Prevention Registry (www.endALZnow.org) will collect contact and demographic information on individuals. The objective is to provide information the latest news and advances in Alzheimer's prevention research, and to inform enrollees about research studies in their community. Enrolled individuals will receive regular email communications. As research studies become available, individuals will be notified via email with information as to how proceed should they be interested. Regi... Read More
Gender:
All
Ages:
Between 18 years and 110 years
Trial Updated:
08/02/2023
Locations: Banner Alzheimer's Institute, Phoenix, Arizona
Conditions: Alzheimer's Disease, Dementia
Register for Updates
Music Therapy Experiences in Patients With Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD)
NCT04666077
Recruiting
This study compares different music therapy (MT) experiences and their impact on memory and language in patients with Alzheimer's disease and Mild Cognitive Impairment. The 12-month study will assess the role of common experiences involving familiar music and other pleasant events (blinded control) to benefit cognition and measure the quality of life for people with Alzheimer's disease and Mild Cognitive Impairment. Following screening, all participants will meet with a licensed music therapis... Read More
Gender:
All
Ages:
55 years and above
Trial Updated:
05/10/2023
Locations: Louis Armstrong Center for Music and Medicine, Mount Sinai Beth Israel, New York, New York +1 locations
Conditions: Alzheimer's Disease, Mild Cognitive Impairment
Register for Updates