There are currently 47 active clinical trials seeking participants for Autism research studies. The states with the highest number of trials for Autism participants are California, Florida, New York and Ohio.
Sensory Habituation in Autism Spectrum Disorders
Recruiting
Autism spectrum disorder (ASD) is one of the most common developmental disabilities and often people with ASD have sensory processing disorders. These sensory processing disorders are often associated with problem behaviors and, more recently, have been connected to anxiety disorders in people with ASD. While it has been suggested that sensory processing responses in ASD could be malleable, current treatment strategies for sensory processing disorders in ASD have inconsistent results or lack lar... Read More
Gender:
All
Ages:
Between 7 years and 18 years
Trial Updated:
01/30/2024
Locations: University of Nebraska Medical Center, Munroe-Meyer Insitute, Omaha, Nebraska
Conditions: Autism Spectrum Disorder, Autism, Sensory Processing Disorder, Sensory Over-Responsivity
Implementation of the Parents Taking Action in Paraguay
Recruiting
The principal aim of this study is to conduct a single group design pilot of a psychoeducational caregiver training (i.e., culturally adapted Parents Taking Action) with a group of family caregivers of young children with autism in Paraguay. The following research questions will be addressed: Research Question #1: What is the feasibility and acceptability of the intervention? Research Question #2: Do participants improve between pre and post-test on outcome measures? Parents will receive 10 wee... Read More
Gender:
All
Ages:
Between 18 years and 100 years
Trial Updated:
01/04/2024
Locations: University of Texas at Austin, Austin, Texas
Conditions: Depression, Autism
Neuroimaging Predictors of Improvement to Pivotal Response Treatment (PRT) in Young Children With Autism
Recruiting
Autism spectrum disorder (ASD) is a very heterogeneous disorder with limited empirically validated behavioral and biological interventions. The goal of this pilot investigation is to apply a biologically-based approach to identify predictors of treatment response in children with ASD who are receiving Pivotal Response Treatment (PRT), an evidence-based behavioral intervention. Specifically, the investigators propose to identify neuroimaging biomarkers of treatment response to a PRT program (PRT-... Read More
Gender:
All
Ages:
Between 2 years and 4 years
Trial Updated:
12/13/2023
Locations: Stanford University, Stanford, California
Conditions: Autism Spectrum Disorder, Autism
Transcranial Photobiomodulation Therapy for the Treatment of Autistic Traits in Children and Adolescents With ADHD
Recruiting
An open label trial to assess the safety and efficacy of transcranial photobiomodulation (tPBM) in improving autistic traits in ADHD youth.
Gender:
All
Ages:
Between 9 years and 17 years
Trial Updated:
12/07/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Autism, Attention Deficit Hyperactivity Disorder
A Pilot Participatory Program Evaluation of a Virtual Trauma Support Program for Autistic Adults
Recruiting
The goal of this single-group clinical trial is to learn about the initial efficacy and feasibility of telehealth-delivered Written Exposure Therapy (WET) for autistic adults with traumatic stress symptoms. The main questions the investigators aim to answer are: Do symptoms of posttraumatic stress disorder (PTSD) and co-occurring mental health concerns decrease after receiving WET? Do biobehavioral health outcomes, including objective (Fitbit indicators of activity, sleep, and heart rate) and s... Read More
Gender:
All
Ages:
18 years and above
Trial Updated:
12/06/2023
Locations: University of Wyoming, Laramie, Wyoming
Conditions: Autism, Trauma, Posttraumatic Stress Disorder, Posttraumatic Stress Symptom
Efficacy of Reading Intervention on the Brain Connectivity in Autism
Recruiting
The overarching goal of this proposal is to test the impact of a comprehensive reading intervention program (Visualizing and Verbalizing) on changing the neurobiological mechanisms underlying reading comprehension deficits in children with autism spectrum disorders (ASD). To this end, the investigators will test a group of children with ASD and NT control participants who share common characteristic of average level decoding along with below average reading comprehension. Inclusion of an additio... Read More
Gender:
All
Ages:
Between 7 years and 13 years
Trial Updated:
11/29/2023
Locations: University of Alabama, Tuscaloosa, Alabama
Conditions: Autism Spectrum Disorder, Autism, Reading Problem
Achieving Steady Work Among Adults With Autism Through Specialized Employment Program
Recruiting
Individuals with autism spectrum disorder (ASD) have significantly higher levels of unemployment and underemployment compared to their typically developing peers and all other groups with neurodevelopmental disorders, even though major companies that have employed and trained young people with ASD acclaim their significant innovations in their companies. The investigators hope to examine the effects of specialized employment support programs, over current traditional vocational rehabilitation ap... Read More
Gender:
All
Ages:
Between 18 years and 55 years
Trial Updated:
11/22/2023
Locations: Stanford University School of Medicine, Palo Alto, California
Conditions: Autism Spectrum Disorder, Autism
Natural History Study of Individuals With Autism and Germline Heterozygous PTEN Mutations
Recruiting
The purpose of this study is to determine cross-sectional and longitudinal medical, behavioral, and cognitive differences between PTEN ASD and other groups, as well as to identify cognitive, neural systems, and molecular biomarkers specific to PTEN ASD. In addition, this study will be creating and maintaining a biorepository and linked phenotypic database for PTEN ASD.
Gender:
All
Ages:
18 months and above
Trial Updated:
11/09/2023
Locations: University of California at Los Angeles, Los Angeles, California +4 locations
Conditions: PTEN, ASD, Autism, Macrocephaly, PTEN Hamartoma Tumor Syndrome
Project AFECT (Autism Family Empowerment Coaching and Training Program)
Recruiting
The goal of this clinical trial is to learn about the journey of families after their child's diagnosis of autism and to help parents understand autism and get the right treatments for their child. This study is for parents of children just diagnosed with autism who are: Age greater than 1 and up to 5 years old; Hispanic/Latino OR Black/African-American OR have Medi-Cal as primary health insurance; AND Live in one of the following counties in California (Alameda, Contra Costa, Marin, Monterey,... Read More
Gender:
All
Ages:
Between 12 months and 60 months
Trial Updated:
10/13/2023
Locations: Gardner Packard Children's Health Center, Atherton, California +1 locations
Conditions: Autism Spectrum Disorder, Autism, Autism Spectrum Disorders, Autistic Disorder, Autistic Spectrum Disorder, Autistic Spectrum Disorders, Autistic Disorders Spectrum
Memantine for the Treatment of Social Deficits in Youth With Disorders of Impaired Social Interactions
Recruiting
This study is a 12-week randomized-controlled trial of memantine hydrochloride (Namenda) for the treatment of social impairment in youth with Non-Verbal Learning Disorder, High-Functioning Autism Spectrum Disorder, and related conditions. Eligible participants will be males and females ages 8-18. This study consists of up to 6 visits to Massachusetts General Hospital.
Gender:
All
Ages:
Between 8 years and 18 years
Trial Updated:
09/07/2023
Locations: Massachusetts General Hospital, Boston, Massachusetts
Conditions: Autism, Autism Spectrum Disorder, Nonverbal Learning Disability
Trial of Diphenhydramine for Sleep in Children With Autism
Recruiting
The purpose of this study is to examine the effect of diphenhydramine on sleep in children and adolescents with Autism Spectrum Disorder (ASD). Diphenhydramine is an anti-histaminergic agent with strong hypnotic properties. To accomplish this, the investigators will use a randomized double-blind placebo-controlled crossover 8-week study design to examine the effect of diphenhydramine on sleep physiology as assessed by polysomnography (PSG), actigraphy, circadian rhythm, and clinical measures.
Gender:
All
Ages:
Between 8 years and 17 years
Trial Updated:
09/05/2023
Locations: Stanford University, Stanford, California
Conditions: Autism, Autism Spectrum Disorder
The Effectiveness of an Autistic-delivered Peer-support Intervention for Autistic Adults: Community Autism Peer Specialist (CAPS) Program
Recruiting
The number of autistic adults reached 5.4 million in the United States in 2017 and is projected to continue to rise, but evidence-based practices to optimize their health and well-being are limited and poor outcomes are common. This study will leverage existing infrastructure to finalize the development of a novel support service provided by peers with lived experience, incorporating input from autistic peer specialists, autism researchers, peer support researchers, and experts in peer support t... Read More
Gender:
All
Ages:
Between 18 years and 30 years
Trial Updated:
09/05/2023
Locations: Drexel University, Philadelphia, Pennsylvania
Conditions: Autism